Safety and immunogenicity of hepatitis A vaccine in human immunodeficiency virus-infected patients: A double-blind, randomized, placebo-controlled trial

Journal of Infectious Diseases

Volumn 187, Issue 8, 2003, Pages 1327-1331

  Kemper, Carol A ^a,b   Haubrich, Richard ^c   Frank, Ian ^d   Dubin, Gary ^e   Buscarino, Charles ^e   McCutchan, J Allen ^c   Deresinski, Stanley C ^a,b  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e Univ CA San Diego Antiviral Res C ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; HEPATITIS A VACCINE; PLACEBO;

ADULT; AGED; ANALYSIS OF VARIANCE; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG TOLERABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FATIGUE; FEMALE; FEVER; HEADACHE; HEPATITIS A; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGENICITY; INJECTION SITE; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NAUSEA; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEROPREVALENCE; T LYMPHOCYTE; VIRUS LOAD; VOMITING;

CD4 LYMPHOCYTE COUNT; DOUBLE-BLIND METHOD; HEPATITIS A; HEPATITIS A VACCINES; HEPATITIS A VIRUS; HIV INFECTIONS; HUMANS; TIME FACTORS; VIRAL LOAD;

EID: 0345269168     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/374562     Document Type: Article

References (18)

1. Ridolfo AL, Rusconi S, Antinori S, Balotta C, Galli M. Persisting HIV-1 replication triggered by acute hepatitis A virus infection. Antivir Ther 2000; 5:15-7.
2. Clemens R, Safary A, Hepburn A, Roche C, Stanbury WI, André FE. Clinical experience with an inactivated hepatitis A vaccine. J Infect Dis 1995; 171(Suppl 1):S44-9.
3. Neilsen GA, Bodsworth NJ, Watts N. Response to hepatitis A vaccination in human immunodeficiency virus-infected and -uninfected homosexual men. J Infect Dis 1997; 176:1064-7.
4. Santagostino E, Gringeri A, Rocino A, Zanetti A, deBiasi R, Mannucci PM. Patterns of immunogenicity of an inactivated hepatitis A vaccine in anti-HIV positive and negative hemophilic patients. Thromb Haemost 1994; 72:508-10.
5. Tilzey AJ, Palmer SJ, Harrington C, O'Doherty MJ. Hepatitis A vaccine responses in HIV-positive persons with haemophilia. Vaccine 1996; 14:1039-41.
6. Hess G, Clemens R, Bienzle U, Schonfeld C, Schunck B, Bock HL. Immunogenicity and safety of an inactivated hepatitis A vaccine in anti-HIV positive and negative homosexual men. J Med Virol 1995; 46:40-2.
7. Günthard HF, Wong JK, Spina CA, et al. Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy. J Infect Dis 2000; 181:522-31.
8. O'Brien WA, Grovit-Ferbas K, Namazi A, et al. HIV type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination. Blood 1995; 86:1082-9.
9. Stanley SK, Ostrowski MA, Justement JS, et al. Effect of immunization with a common recall antigen on viral expression in patients infected with human immunodeficiency virus type 1. N Engl J Med 1996; 334:1222-30.
10. Centers for Disease Control and Prevention. 1993 Revised classification system for HIV infection and expanded surveillance case definition of AIDS among adolescents and adults. MMWR Recomm Rep 1992; 41(RR-17):1-19.
11. Kroon FP, van Dissell JT, de Jong JC, van Furth R. Antibody response to influenza, tetanus and pneumococcal vaccines in HIV-seropositive individuals in relation to the number of CD4 lymphocytes. AIDS 1994; 8:469-76.
12. Opravil M, Matter FL, Blaser J, Lüthy R. Poor antibody response after tetanus and pneumococcal vaccination in immunocompromised, HIV-infected patients. Clin Exp Immunol 1991; 84:185-9.
13. Keet IPM, van Doornum G, Salary A, Coutinho RA. Insufficient response to hepatitis B vaccination in HIV-positive homosexual men. AIDS 1992; 6:509-10.
14. Wong EKL, Bodsworth NJ, Slade MA, Mulhall BP, Donovan B. Response to hepatitis B vaccination in a primary care setting: influence of HIV infection, CD4 lymphocyte count, and vaccination schedules. Int J STD AIDS 1996; 7:490-4.
15. Zanetti AR, Mannucci PM, Tanzi E, et al. Hepatitis B vaccination of 113 hemophiliacs: lower antibody response in anti-LAV/HTLV-III-positive patients. Am J Hematol 1986; 23:339-45.
16. Mannucci PM, Zanetti AR, Gringeri A, et al. Long-term immunogenicity of a plasma-derived hepatitis B vaccine in HIV seropositive and HIV seronegative hemophiliacs. Arch Intern Med 1989; 149:1333-7.
17. Bodsworth NJ, Neilsen GA, Donovan B. The effect of immunization with inactivated hepatitis A vaccine on the clinical course of HIV-1 infection: 1 year follow-up. AIDS 1997; 11:747-9.
18. Wallace MR, Tasker SA, Earhart KC, Brandt C, Kuter B. Hepatitis A vaccination response in HIV-infected and uninfected subjects [abstract 379]. In: Program and abstracts of the 39th annual meeting of the Infectious Diseases Society of America (San Francisco). Alexandria, VA: Infectious Diseases Society of America, 2001:1153.