Therapeutic efficacy of tumor-derived heat shock protein 70 immunotherapy combining interleukin-2 on tumor-bearing mice

Chinese Medical Journal

Volumn 116, Issue 2, 2003, Pages 288-291

  Fu, Qingguo ^a   Meng, Fandong ^a   Shen, Xiaodong ^a   Guo, Renxuan ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Heat shock protein 70; Interleukin 2; Neoplasm

Indexed keywords

CYTOKINE; HEAT SHOCK PROTEIN 70; INTERLEUKIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CANCER TRANSPLANTATION; CAPILLARY ELECTROPHORESIS; CELL CULTURE; CONTROLLED STUDY; DRUG EFFICACY; EXTRACTION; FEMALE; LIFESPAN; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN PURIFICATION; STATISTICAL SIGNIFICANCE; SURVIVAL TIME; TUMOR REGRESSION; WESTERN BLOTTING;

ANIMALS; DRUG THERAPY, COMBINATION; HSP70 HEAT-SHOCK PROTEINS; INTERLEUKIN-2; MICE; MICE, INBRED STRAINS; NEOPLASMS, EXPERIMENTAL; SURVIVAL RATE; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED;

EID: 0345269065     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Ferrarini M, Heltai S, Zocchi MR, et al. Unusual expression and localization of heat-shock proteins in human tumor cells. Int J Cancer 1992;51:613-619.
2. Srivastava PK, Udono H, Blachere NE, et al. Heat shock protein transfer peptides during antigen processing and CTL priming. Immunogenetics 1994;39:93-98.
3. Foa R, Guarim A, Gansbacher B. IL-2 treatment for cancer: from biology to therapy. Br J Cancer 1992;66:992-998.
4. Li C, Yan W, Hao Y, et al. Killing effect of interleukin-2 and interferon-alpha activated leukemic bone marrow in remission on K562 leukemic cells. Chin Med J 1999;112:53-55.