Fate of 3H- and 14C-Labeled Emamectin Benzoate in Lactating Goats

Journal of Agricultural and Food Chemistry

Volumn 45, Issue 1, 1997, Pages 253-259

  Mushtaq, Mohammad ^a   Allen, Loretta R S ^a   Crouch, Louis S ^a   Wislocki, Peter G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

4 deoxy 4 (epi methylamino)avermectin B1a; Abamectin; Emamectin; Goat; HPLC; Metabolism; MK 0244; Pesticide; Residues

Indexed keywords

CAPRA HIRCUS;

EID: 0345260804     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9604089     Document Type: Article

References (15)

1. Burg, R. W.; Miller, B. M.; Baker, E. E.; Birnbaum, J.; Currie, S. A.; Hartman, R.; Kong, Y.-L.; Monaghan, R. L.; Olson, G.; Putter, I.; Tunac, J. B.; Wallick, H.; Stapley, E. O.; Oiwa, R.; Omura, S. Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism And Fermentation. Antimicrob. Agents Chemother. 1979, 15, 361-367.
2. Campbell, W. C.; Burg, R. W.; Fisher, M. H.; Dybas, R. A. The Discovery of Ivermectin and Other Avermectins. In Pesticide Synthesis Through Rational Approaches; Magee, P. S., Kohn, G. K., Menn, J. J., Eds.; ACS Symposium Series 255; American Chemical Society: Washington, DC, 1984; pp 5-20.
3. 14C]Clorsulon in Cow's Milk. J. Agric. Food Chem. 1989, 37, 819-823.
4. Chiu, S.-H. L.; Green, M. L.; Baylis, F. P.; Eline, D.; Rosegay, A.; Meriwether, H.; Jacob, T. A. Absorption, Tissue Distribution and Excretion of Tritium-Labeled Ivermectin in Cattle, Sheep, and Rats. J. Agric. Food Chem. 1990, 38, 2072-2078.
5. Dybas, R. A.; Hilton, N. J.; Babu, J. R.; Preiser, F. A.; Dolce, G. J. Novel Second Generation Avermectin Insecticides and Miticides for Crop Protection. In Novel Microbial Products for Medicine and Agriculture; Demain, A. L., Somkuti, G. A., Hunter-Cevera, J. C., Rossmoore, H. W., Eds.; Elsevier Press: New York, 1989; pp 203-212.
6. Lasota, J. A.; Dybas, R. A. Avermectins, A Novel Class of Compounds: Implications for Use in Arthropod Pest Control. Annu. Rev. Entomol. 1991, 36, 91-117.
7. Long, C. The Chemical Composition of Milk, Colostrum and Mammary Gland. Biochemists' Handbook: D. Van Nostrand Co. Inc.: Princeton, NJ, 1968; pp 895-896.
8. 1a in Rats. J. Agric. Food Chem. 1989a, 37, 1487-1491.
9. 1a in Lactating Goats. J. Agric. Food Chem. 1989b, 37, 1491-1497.
10. 1a in Rats. J. Agric. Food Chem. 1990, 38, 864-870.
11. 14C-Labeled Emamectin Benzoate in Rats. J. Agric. Food Chem. 1996, 44, 3342-3349.
12. 1 Benzoate (MK-0244) and its Delta 8,9-Isomer in Celery and Lettuce by HPLC with Fluorescence Detection. J. Agric. Food Chem. 1991, 39, 2226-2230.
13. Putter, I.; MacConnell, J. G.; Preiser, F. A.; Haidri, A. A.; Ristich, S. S.; Dybas, R. A. Avermectins: Novel Insecticides, Acaricides and Nematicides from Soil Organism. Experientia 1981, 37, 963-964.
14. 1 in Rats. Drug Metab. Dispos. 1996, 24, 572-578.
15. Zulalian, J.; Stout, S. J.; daCunha, A. R.; Garces, T.; Miller. P. Absorption, Tissue Distribution, Metabolism, and Excretion of Moxidectin in Cattle. J. Agric. Food Chem. 1994, 42, 381-387.