Substitution of leucine 8 in the simian immunodeficiency virus matrix protein impairs particle formation without affecting N-myristylation of the gag precursor

Virology

Volumn 240, Issue 1, 1998, Pages 27-35

  González, Silvia A ^a   Affranchino, José L ^a  

^a Centro de Virologia Animal   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GLUTAMINE; LEUCINE; MATRIX PROTEIN; MUTANT PROTEIN; MYRISTIC ACID; PROTEIN PRECURSOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYDROPHOBICITY; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINIA VIRUS; VIRUS PARTICLE;

EID: 0345196001     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8919     Document Type: Article

References (31)

1. Bryant M., Ratner L. Myristoylation-dependent replication and assembly of human immunodeficiency virus 1. Proc. Natl. Acad. Sci. USA. 87:1990;523-527.
2. Chakrabarti L., Guyader M., Alizon M., Daniel M. D., Desrosiers R. C., Tiollais P., Sonigo P. Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses. Nature (London). 328:1987;543-547.
3. Daniel M. D., Letvin N. L., King N. W., Kannagi M., Sehgal P. K., Hunt R. D., Kanki P. J., Essex M., Desrosiers R. C. Isolation of a T-cell tropic HTLV-III-like retrovirus from macaques. Science. 228:1985;1201-1204.
4. Delchambre M., Gheysen D., Thines D., Thiriart C., Jacobs E., Verdin E., Horth M., Burny A., Bex F. The Gag precursor of the simian immunodeficiency virus assembles into virus-like particles. EMBO J. 8:1989;2653-2660.
5. Desrosiers R. C. The simian immunodeficiency viruses. Annu. Rev. Immunol. 42:1988;607-625.
6. SMM-PBj14. Nature (London). 345:1990;636-639.
7. Ebbets-Reed D., Scarlata S., Carter C. A. The major homology region of the HIV-1 Gag precursor influences membrane affinity. Biochemistry. 35:1996;14268-14275.
8. Fäcke M., Janetzko A., Schoeman R. L., Kräusslich H.-G. A large deletion in the matrix domain of the human immunodeficiency virusgag. J. Virol. 67:1993;4972-4980.
9. Franchini G., Gurgo C., Gupo H. G., Gallo R. C., Collalti E., Fargnoli K. A., Hall L. F., Wong-Staal F., Reitz M. S. Sequence of simian immunodeficiency virus and its relationship to the human immunodeficiency viruses. Nature (London). 328:1987;539-543.
10. Gelderblom H. R., Hausmann E. H. S., Ozel M., Pauli G., Koch M. A. Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology. 156:1987;171-176.
11. González S. A., Affranchino J. L. Mutational analysis of the conserved cysteine residues in the simian immunodeficiency virus matrix protein. Virology. 210:1995;501-507.
12. González S. A., Affranchino J. L., Gelderblom H. R., Burny A. Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles. Virology. 194:1993;548-556.
13. González S. A., Burny A., Affranchino J. L. Identification of domains in the simian immunodeficiency virus matrix protein essential for assembly and envelope glycoprotein incorporation. J. Virol. 70:1996;6384-6389.
14. Granowitz C., Goff S. P. Substitution mutations affecting a small region of the Moloney murine leukemia virus MA Gag protein block assembly and release of virion particles. Virology. 205:1994;336-344.
15. Mne. J. Virol. 62:1988;2587-2595.
16. Henderson L. E., Sowder R. C., Copeland T. D., Oroszlan S., Benveniste R. E. Gag precursors of HIV and SIV are cleaved into six proteins found in the mature virions. J. Med. Primatol. 19:1990;411-419.
17. Hockley D. J., Wood R. D., Jacobs J. P., Garrett A. J. Electron microscopy of human immunodeficiency virus. J. Gen. Virol. 69:1988;2455-2469.
18. Johnson D. R., Bhatnagar R. S., Knoll L. J., Gordon J. I. Genetic and biochemical studies of protein N-myristoylation. Annu. Rev. Biochem. 63:1994;869-914.
19. Kaplan J. M., Mardon J., Bishop J. M., Varmus H. E. The first seven amino acids encoded by the v-src. Mol. Cell. Biol. 8:1988;2435-2441.
20. Kyte J., Doolittle R. F. A simple method for displaying the hydrophobic character of a protein. J. Mol. Biol. 157:1982;105-132.
21. Letvin N. L., Daniel M. D., Sehgal P. K., Desrosiers R. C., Hunt R. D., Waldron L. M., MacKey J. J., Schmidt D. K., Chalifoux L. V., King N. W. Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science. 230:1985;71-73.
22. McLaughlin S., Aderem A. The myristoyl-electrostatic switch: A modulator of reversible protein-membrane interaction. Trends Biochem. Sci. 20:1995;272-276.
23. Mergener K., Fäcke M., Weber R., Brinkmann V., Gelderblom H. R., Kräusslich H.-G. Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells. Virology. 186:1992;25-39.
24. Myers, G. Wain-Hobson, S. Korber, B. Smith, R. F. Pavlakis, G. N. 1993, Human Retroviruses and AIDS. A Compilation and Analysis of Nucleic Acids and Amino Acids Sequences, Los Alamos National Laboratory, Los Alamos, NM.
25. gagand is incorporated into viruslike particles. J. Virol. 66:1992;6304-6313.
26. gagin membrane association in a cell-free system: Requirements for a C-terminal domain. Proc. Natl. Acad. Sci. USA. 91:1994;4594-4598.
27. Rao Z., Belyaev A. S., Fry E., Roy P., Jones I. M., Stuart D. I. Crystal structure of SIV matrix antigen and implications for virus assembly. Nature (London). 378:1995;743-747.
28. Spearman P., Wang J.-J., Vander Heyden N., Ratner L. Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly. J. Virol. 68:1994;3232-3242.
29. Yuan X., Yu X., Lee T.-H., Essex M. Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intracellular transport of the Gag precursor. J. Virol. 67:1993;6387-6394.
30. Zhou W., Parent L. J., Wills J. W., Resh M. D. Identification of a membrane binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids. J. Virol. 68:1994;2556-2569.
31. Zhou W., Resh M. D. Differential membrane binding of the human immunodeficiency virus type 1 matrix protein. J. Virol. 70:1996;8540-8548.