Perceptual correlates of changes in cortical representation of fingers in blind multifinger Braille readers

Journal of Neuroscience

Volumn 18, Issue 11, 1998, Pages 4417-4423

  Sterr, Annette ^a   Müller, Matthias M ^a   Elbert, Thomas ^a   Rockstroh, Brigitte ^a   Pantev, Christo ^b   Taub, Edward ^c  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Blindness; Braille reading; Cortex; Cortical reorganization; Organization; Semmes Weinstein monofilaments; Sensory deafferentation; Somatosensory; Tactile perception

Indexed keywords

ADULT; ARTICLE; BLINDNESS; BRAILLE; BRAIN CORTEX; HUMAN; HUMAN EXPERIMENT; NERVE CELL NETWORK; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; TACTILE DISCRIMINATION;

EID: 0345195993     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-11-04417.1998     Document Type: Article

References (27)

1. Allard T, Clark SA, Jenkins WM, Merzenich MM (1991) Reorganization of somatosensory area 3b representations in adult owl monkeys after digital syndactyly. J Neurophysiol 66:1048-1058.
2. Birbaumer N, Lutzenberger W, Monotya P, Larbig W, Unertl K, Töpfner S, Grodd W, Taub E, Flor H (1997) Effects of regional anesthesia on phantom limb pain are mirrored in changes in cortical reorganization. J Neurosci 17:5503-5508.
3. Byl NN, Merzenich MM, Jenkins WM (1996) A primate genesis model of focal dystonia and repetitive strain injury:I. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys. Neurology 47:508-520.
4. Byl NN, Merzenich MM, Cheung S, Bodenbaugh P, Nagarajan SS, Jenkins WM (1997) A primate model for studying focal dystonia and repetitive strain injury:effects on the primary somatosensory cortex. Phys Ther 77:269-284.
5. Clark SA, Allard T, Jenkins WM, Merzenich MM (1988) Receptive fields in the body-surface map in adult cortex defined by temporally correlated inputs. Nature 332:444-445.
6. Elbert T, Flor H, Birbaumer N, Knecht S, Hampson S, Larbig W, Taub E (1994) Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury. NeuroReport 5:2593-2597.
7. Elbert T, Pantev C, Wienbruch C, Hoke M, Rockstroh B, Taub E (1995) Increased use of the left hand in string players associated with increased cortical representation of the fingers. Science 220:21-23.
8. Elbert T, Sterr A, Candia C, Rockstroh B, Taub E (1996) Representational cortical plasticity as revealed by magnetic source imaging:how the brain learns to play the violin. First Berlin Workshop On Cortical Plasticity, Berlin, November.
9. Elbert T, Sterr A, Flor H, Rockstroh B, Knecht S, Pantev C, Wienbruch C, Taub E (1997) Input-increase and input-decrease types of cortical reorganization after upper limb extremity amputation in humans. Exp Brain Res 117:161-164.
10. Flor H, Elbert T, Knecht S, Wienbruch C, Pantev C, Birbaumer N, Larbig W, Taub E (1995) Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 375:482-484.
11. Flor H, Braun C, Elbert T, Birbaumer N (1997) Extensive reorganization of primary somatosensory cortex in chronic back pain. Neurosci Lett 224:5-8.
12. Florence SL, Kaas JH (1995) Large-scale reorganization at multiple Jevels of the somatosensory pathway follows therapeutic amputation of the hand in monkeys. J Neurosci 15:8083-8095.
13. Jenkins WM, Merzenich MM, Ochs MT, Allard T, Guic-Robles E (1990) Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation. J Neurophysiol 63:82-104.
14. Knecht S, Henningsen H, Elbert T, Flor H, Hoehling C, Pantev C, Taub E (1996) Reorganizational and perceptual changes after amputation. Brain 119:1213-1219.
15. Merzenich MM, Nelson RJ, Stryker MP, Cynader MS, Schoppmann A, Zook JM (1984) Somatosensory cortical map changes following digit amputation in adult monkeys. J Comp Neurol 224:591-605.
16. Mogilner A, Grossman JAI, Ribary U, Joliot M, Volkmann J, Rapaport D, Beasley RW, Llinas RR (1993) Somatosensory cortical plasticity in adult humans revealed by magnetoencephalograhy. Proc Natl Acad Sci USA 90:3593-3597.
17. Mühlnickel W, Elbert T, Taub E, Flor H (1998) Deviations from the tonotopic map are correlated with tinnitus strength. In:Advances in biomagnetism research:Biomag96, Vol II Aine C, Okada Y, Stroink G, Swithenby S, Wood C, (eds). New York:Springer-Verlag.
18. Pascual-Leone A, Cammarota A, Wassermann EM, Brasil-Neto JP, Cohen LG, Hallett M (1993) Modulation of motor cortical outputs to the reading hand of Braille readers. Ann Neurol 34:33-37.
19. Pons TP, Garraghty PE, Ommaya AK, Kaas JH, Taub E, Mishkin M (1991) Massive cortical reorganisation after sensory deafferentation in adult macaques. Science 252:1857-1860.
20. Recanzone G, Allard TT, Jenkins WM, Merzenich MM (1990) Receptive-field changes induced by peripheral nerve stimulation in SI of adult rats. J Neurophysiol 63:1213-1225.
21. Recanzone GH, Jenkins WM, Hradek GT, Merzenich MM (1992a) Progressive improvement in discriminative abilities in adult owl monkeys performing a tactile discrimination task. J Neurophysiol 67:1015-1030.
22. Recanzone GH, Merzenich MM, Jenkins WM (1992) Frequency discrimination training engaging a restricted skin surface results in an emergence of a cutaneous response zone in cortical area 3a. J Neurophysiol 67:1057-1070.
23. Recanzone GH, Merzenich MM, Jenkins WM, Grajski KA, Dinse HR (1992c) Topographic reorganization of the hand representation in cortical area 3b of owl monkeys trained in a frequency-discrimination task. J Neurophysiol 67:1031-1056.
24. Rockstroh B, Vanni S, Elbert T, Hari R (1998) Extensive somatosensory stimulation alters somatosensory evoked fields. In:Advances in biomagnetism research:Biomag96 International Conference on Bio magnetism. Aine C, Okada Y, Stroink G, Swithenby S, Wood C, (eds). New York:Springer-Verlag.
25. Sterr A, Müller MM, Elbert T, Rockstroh B. Pantev C, Taub E (1998) Changed perception in Braille-readers. Nature 1998:134-135.
26. Wang X, Merzenich MM, Sameshima K, Jenkins WM (1995) Remodelling of hand representation in adult cortex determined by timing of tactile stimulation. Nature 378:71-75.
27. Yang TT, Gallen CC, Ramachandran VS, Cobb S, Schwartz BJ, Blum FB (1994) Noninvasive detection of cerebral plasticity in adult human somatosensory cortex. NeuroReport 5:701-704.