Mutagenic activation of aromatic amines by molluscs as a biomarker of marine pollution

Environmental and Molecular Mutagenesis

Volumn 31, Issue 3, 1998, Pages 282-291

  Diaz Mendez F M ^a   Rodriguez Ariza A ^a   Usero Garcia J ^b   Pueyo, C ^a   Lopez Barea J ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

2 aminoanthracene activation; Chamelea gallina; Environmental pollution; Monooxygenases; Mutagenic activity; Mytilus edulis

Indexed keywords

2 AMINOANTHRACENE; AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE; BIOLOGICAL MARKER; ETHOXYRESORUFIN DEETHYLASE; PETROLEUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVATION; ENVIRONMENTAL MONITORING; ENZYME ACTIVITY; MOLLUSC; MUTAGENIC ACTIVITY; NONHUMAN; SALMONELLA TYPHIMURIUM; SEA POLLUTION;

2-ACETYLAMINOFLUORENE; ACETYLTRANSFERASES; ANIMALS; ANTHRACENES; ATLANTIC OCEAN; BACTERIAL PROTEINS; BENZOFLAVONES; BETA-NAPHTHOFLAVONE; BIOLOGICAL ASSAY; BIOTRANSFORMATION; BIVALVIA; CYTOCHROME P-450 CYP1A1; CYTOSOL; FUEL OILS; METALS, HEAVY; METHIMAZOLE; MICROSOMES; MOLLUSCA; MUTAGENICITY TESTS; PRODRUGS; PYRENES; SALMONELLA TYPHIMURIUM; WATER POLLUTANTS, CHEMICAL; WATER POLLUTION;

ANIMALIA; BIVALVIA; CHAMELEA GALLINA; INVERTEBRATA; MOLLUSCA; MYTILUS EDULIS; SALMONELLA TYPHIMURIUM; TYPHIMURIUM; VERTEBRATA;

EID: 0345195191     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1998)31:3<282::AID-EM10>3.0.CO;2-8     Document Type: Article

References (35)

1. Al-Mossawi MAJ, Kadri M, Salama M, Salem A (1982): The efficiency of various solvents in the extraction of chemical mutagens from living tissues: A comparative study. Mutat Res 104:43-48.
2. Ayrton AD, Neville S, Ioannides C (1992): Cytosolic activation of 2-aminoanthracene: Implications in its use as diagnostic mutagen in the Ames test. Mutat Res 265:1-8.
3. Britvic S, Kurelec B (1986): Selective activation of carcinogenic aromatic amines to bacterial mutagens in the marine mussel Mytilus galloprovincialis. Comp Biochem Physiol 85C:111-114.
4. Buhler DR, Williams DE (1988): The role of biotransformation in the toxicity of chemicals. Aquat Toxicol 11:19-28.
5. Davis RW, Botstein D, Roth JR (1980): "A Manual for Genetic Engineering. Advanced Bacterial Genetics." New York: Cold Spring Harbor Laboratory Press.
6. Goldberg ED, Bowen VT, Farrington JW, Harvey G, Martin JH, Parker PL, Risebrough RW, Robertson W, Schneider W, Gamble E (1978): The mussel watch. Environ Conserv 5:101-125.
7. Jurado J, Alejandre-Duran E, Pueyo C (1994): Mutagenicity testing in Salmonella typhimurium strains possessing both the His reversion and Ara forward mutation systems and different levels of classical nitroreductase or O-acetyltransferase activities. Environ Mol Mutagen 23:286-293.
8. Lebo JA, Zajicek JL, Schwartz TR, Smith LM, Beasley MP (1991): Determination of monocyclic and polycyclic aromatic hydrocarbons in fish tissue. J Assoc Off Anal Chem 74:538-544.
9. Livingstone DR (1985): Responses of detoxication/toxication enzyme systems of molluscs to organic pollutants and xenobiotics. Mar Pollut Bull 16:158-164.
10. Livingstone DR (1991): Towards a specific index of impact by organic pollution for marine invertebrates. Comp Biochem Physiol 100C:151-155.
11. Livingstone DR, Kirchin MA, Wiseman A (1989): Cytochrome P-450 and oxidative metabolism in molluscs. Xenobiotica 19:1041-1062.
12. Livingstone DR, Donkin P, Walker CH (1992): Pollutants in marine ecosystems: An overview. In Walker CH, Livingstone DR (eds): "Persistent Pollutants in Marine Ecosystems" Oxford: Pergamon Press, pp 235-263.
13. Lowry OH, Rosebrogh MJ, Farr AL, Randall RJ (1951): Protein measurement with the Folin phenol reagents. J Biol Chem 193:265-275.
14. Maron DM, Ames BN (1983): Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173-215.
15. Marsh JW, Chipman JK, Livingstone DR (1992): Activation of xenobiotics to reactive and mutagenic products by the marine invertebrates Mytilus edulis, Carcinus maenas and Asterias rubens. Aquat Toxicol 22:115-127.
16. Michel XR, Cassand PM, Narbonne JF (1993): Activation of benzo(a)-pyrene and 2-aminoanthracene to bacteria mutagens by mussels digestive gland postmitochondrial fraction. Mutat Res 301:113-119.
17. Nebert DW, Gonzalez FJ (1987): P450 genes: Structure, evolution and regulation. Annu Rev Biochem 56:945-993.
18. Okey AB (1990): Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 45:241-298.
19. Pelroy RA, Gandolfi AJ (1980): Use of mixed function amine oxidase for metabolic activation in the Ames/Salmonella assay system. Mutat Res 72:329-334.
20. Porte C, Lemaire P, Peters LD, Livingstone DR (1995): Partial purification of cytochrome P450 from digestive gland microsomes of the common mussel, Mytilus edulis L. Mar Environ Res 39:27-31.
21. Rodríguez-Ariza A, Dorado G, Navas JI, Pueyo C, López-Barea J (1994): Promutagen activation by fish liver as biomarker of littoral pollution. Environ Mol Mutagen 24:116-123.
22. Rodríguez-Ariza A, Díaz-Méndez FM, Navas JI, Pueyo C, López-Barea J (1995): Metabolic activation of carcinogenic aromatic amines by fish exposed to environmental pollutants. Environ Mol Mutagen 25:50-57.
23. Solé M, Porte C, Albaigés J (1995a): The use of biomarkers for assessing the effects of organic pollution in mussels. Sci Total Environ 159:147-153.
24. Solé M, Porte C, Albaigés J (1995b): Seasonal variations in the mixed-function oxygenase system and antioxidant enzymes of the mussel Mytilus galloprovincialis. Environ Toxicol Chem 14:157-164.
25. Steele CM, Ioannides C (1986): Induction of hepatic mixed function oxidases by aromatic amines and its relationship to their bioactivation to mutagens. Mutat Res 162:41-46.
26. Stegeman JJ (1985): Benzo(a)pyrene oxidation and microsomal enzyme activity in the mussel (Mytilus edulis) and other bivalve mollusc species from the western N. Atlantic. Mar Biol 89:21-30.
27. Stegeman JJ, Hahn ME (1994): Biochemistry and molecular biology of monooxygenases: Current perspectives on forms, functions, and regulation of cytochrome P450 in aquatic species. In Malins D, Ostrander GK (eds): "Aquatic Toxicology. Molecular, Biochemical, and Cellular Perspectives" Boca Raton FL: Lewis, pp 87-206.
28. Stegeman JJ, Kloepper-Sams P (1987): Cytochrome P-450 isoenzymes and monooxygenase activity in aquatic animals. Environ Health Perspect 71:87-95.
29. Stegeman JJ, Lech JJ (1991): Cytochrome P-450 monooxygenase systems in aquatic species: Carcinogen metabolism and biomarkers for carcinogen and pollutant exposure. Environ Health Perspect 90:101-109.
30. Timbrell JA (1991): "Principles of Biochemical Toxicology." London: Taylor and Francis, pp 285-288.
31. Tong S, Smith J, Manson D, Gorrod JW, Ioannides C (1986): The metabolic activation of 2-naphthylamine to mutagens in the Ames test. Anticancer Res 6:1107-1112.
32. Usero J, González-Regalado E, Gracia I (1996): Trace metals in the bivalve mollusc Chamelea gallina from the Atlantic coast of Southern Spain. Mar Pollut Bull 12:305-310.
33. Wootton AN, Herring C, Spry JA, Wiseman A, Livingstone DR, Goldfarb PS (1995): Evidence for the existence of cytochrome P450 gene families (CYP1A, 3A, 4A, 11A) and modulation of gene expression (CYP1A) in the mussel Mytilus spp. Mar Environ Res 39:21-26.
34. Ziegler DM (1988): Flavin-containing monooxygenase: Catalytic mechanism and substrate specificities. Drug Metab Rev 19:1-32.
35. Yawetz A, Manelis R, Fishelson L (1992): The effects of Aroclor 1254 and petrochemical pollutants on cytochrome P450 from the digestive gland microsomes of four species of Mediterranean molluscs. Comp Biochem Physiol 103C:607-614.