Enantiomers of thalidomide: Blood distribution and the influence of serum albumin on chiral inversion and hydrolysis

Chirality

Volumn 10, Issue 3, 1998, Pages 223-228

  Eriksson, Tommy ^a,b   Björkman, Sven ^a   Roth, Bodil ^a   Fyge, Åsa ^a   Höglund, Peter ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Blood distribution; Chiral inversion; Human serum albumin; In vitro kinetics; Plasma protein binding; Thalidomide enantiomers

Indexed keywords

SERUM ALBUMIN; THALIDOMIDE;

ARTICLE; BIOTRANSFORMATION; CHIRALITY; CONCENTRATION RESPONSE; DRUG DISTRIBUTION; ENANTIOMER; ENZYME METABOLISM; ERYTHROCYTE MEMBRANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN BINDING;

BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYDROLYSIS; PROTEIN BINDING; SERUM ALBUMIN; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; TERATOGENS; THALIDOMIDE;

EID: 0345191687     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1998)10:3<223::AID-CHIR4>3.0.CO;2-A     Document Type: Article

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