A Capillary Electrophoresis Technique for Evaluating Botulinum Neurotoxin B Light Chain Activity

Journal of Protein Chemistry

Volumn 22, Issue 5, 2003, Pages 441-448

  Adler, Michael ^a   Shafer, Harlan F ^a   Manley, Heather A ^a   Hackley Jr , Brennie E ^a   Nicholson, James D ^a   Keller, James E ^b   Goodnough, Michael C ^c  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c UNIVERSITY OF WISCONSIN   (United States)

Author keywords

Botulinum neurotoxin B; Capillary electrophoresis; Clostridium botulinum; Enzymatic cleavage; VAMP synaptobrevin

Indexed keywords

AMINO ACID; BOTULINUM TOXIN B; PEPTIDE; SYNAPTOBREVIN;

ARTICLE; BOTULISM; CAPILLARY ELECTROPHORESIS; CLOSTRIDIUM BOTULINUM; INTOXICATION; IONIC STRENGTH; NEUROTOXICITY; NONHUMAN; PEPTIDE ANALYSIS; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; THERMOSTABILITY; TOXIN ANALYSIS;

BOTULINUM TOXINS; ELECTROPHORESIS, CAPILLARY; FREEZING; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; KINETICS; MEMBRANE PROTEINS; OSMOLAR CONCENTRATION; R-SNARE PROTEINS; SALTS; TEMPERATURE; ZINC;

CLOSTRIDIUM; CLOSTRIDIUM BOTULINUM;

EID: 0345169964     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOPC.0000005459.00492.60     Document Type: Article

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