Folate Conjugated Doxorubicin-Loaded Membrane Vesicles for Improved Cancer Therapy

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 10, Issue 4, 2003, Pages 277-282

  Mishra, P R ^a,c   Jain, N K ^b  

^a HAMDARD UNIVERSITY   (India)

^b DR H S GOUR UNIVERSITY   (India)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Cancer Therapy; Doxorubicin; Erythrocyte Ghosts; Folic Acid; Membrane Vesicles

Indexed keywords

DOXORUBICIN; FOLIC ACID; N HYDROXYSUCCINIMIDE FOLATE; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG STABILITY; ERYTHROCYTE; MEMBRANE VESICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0345167844     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/drd_10_4_277     Document Type: Article

References (23)

1. Coney, L. R., Tomaselti, A., Carayannopoulas, L., Frasca, V., Kamen, B. A., Colnaught, M. I., and Zurawski, V. R. J. 1991. Cloning of a tumor associated antigen: Moc 18 and Moc 19 antibodies recognize a folate-binding protein. Cancer Res. 51:6125-6132.
2. Deflora, A. 1985. The technology of carrier erythrocytes: A versatile tool for diagnosis and therapy. In Biotechnology in Diagnosis, eds. H. Koprowski, S. Ferrone, and A. Albertini, 223-236, Plenum press.
3. Deloach, J. R. 1983. Encapsulation of exogenous agents in erythrocytes and circulating survival of carrier erythrocytes. J. Appl. Biochem. 5:149-157.
4. Jordon, J. A., Alvarez, F. J., Murciano, J. C., Lotero, A., Herraz, A., Tejedor, M. C., Luque, J., Deloach, J. R., and Dlezin, J. C. 1997. Influence of chemical modification on erythrocyte recognition. In Erythrocytes as Drug Carriers in Medicine, eds. Sprandel and Way, 109-112.
5. Leamon, C. P., and Low, P. S. 1991. Delivery of macromolecules into living cell: A method that exploits folate receptor endocytosis. Proc. Natl. Acad. Sci. USA 88(113):5572-5576.
6. Lejuene, A., Morjani, M., Gicquad, C., Lacroix, J. A., Poyet, P., and Gauderauit, R. C. 1994. Nanoerythrosomes as a new derivative of erythrocyte ghosts: Preparation and antineoplastic potential as drug carrier for daunorubicin. Anticancer Research 14:915-920.
7. Mastrobattista, E., Koning, G. A., and Storm, G. 1999. Immunoliposomes for the targeted delivery of antitumor drugs. Adv. Drug Del. Rev. 40:103-127.
8. Mishra, P. R., and Jain, N. K. 2002a. Biotinylated erythrocytes for enhanced liver uptake "A study on the rat." Int. J. Pharm. 321(2):145-154.
9. Mishra, P. R., and Jain, N. K. 2002b. Improved cancer therapy through folate conjugated 6-MP loaded membrane vesicles. Proc. Int. Symp. Control. Rel. Bioact. Mater. Korea:657.
10. Mishra, P. R., and Jain, N. K. 2000a. Reverse biomembrane vesicles for effective controlled delivery of Doxorubicin. Drug Del. 7:153-159.
11. Mishra, P. R., and Jain, N. K. 2000b. Surface modified methotrexate loaded erythrocytes for enhanced macrophage uptake. J. Drug Targeting 8(4):217-224.
12. Muzykontov, V. R., and Taylor, R. P. 1994. Attachment of biotinylated antibody to red blood cells: Antigen-binding capacity of immunoerythrocytes and their susceptibility to lysis by complement. Anal. Biochem. 223:142-145.
13. Penniston, J. T., and Green, D. E. 1968. The conformational basis of energy transformation in membrane system IV energized states and pinocytosis in erythrocyte ghosts. Arch. Biochem. Biophys. 128:339-350.
14. Reddy, J. A., and Low, P. S. 1998. Folate-mediated targeting of therapeutic and imaging agents to cancers. Crit. Rev. Ther. Drug Carrier Syst. 15:587-627.
15. Rothberg, K. G., Ying, Y. S., Kolghouse, J. F., Kamen, B. A., and Anderson, R. G. 1990. The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin coated pit endocytic pathway. J. Cell Biol. 100:637-649.
16. Schwoch, G., and Passow, H. 1973. Preparation and properties of human erythrocyte ghosts. Mol. Cell Biochem. 2(2):197-215.
17. Seymour, C. A., Muallen, S., and Law, V. L. 1982. Preparation of inside-out vesicles in one step. In Red Cell Membrane, a Methodological Approach, eds. J. C. Ellory, and J. D. Young, 219-221. London: Academic Press.
18. Steck, T. L., Fairbanks, G., and Wallach, D. F. H. 1971. Disposition of the major proteins in the isolated erythrocyte membrane, proteolytic dissection. Biochemistry 10(13):2617-2624.
19. Steck, T. L., Straus, J. H., and Wallach, D. F. H. 1970. Inside-out red cell membrane vesicle: Preparation and purification. Science 168:255-257.
20. Stella, B., Arpicco, S., Peracchia, M. T., Desmaele, D., Hoebeke, J., Renoir, M., D'Angelo, J., Cattel, M., and Couvreur, P. 2000. Design of folic acid-conjugated nanoparticles for drug targeting. J. Pharm. Sci. 89(11):1452-1464.
21. Talwar, N., and Jain, N. K. 1992. Erythrocytes as a carrier for Primaquin: Preparation, characterization and evaluation. J. Control. Rel. 20:133-142.
22. Turek, J. J., Leamaon, C. P., and Low, P. S. 1993. Endocytosis of folate protein conjugate, ultrastructural localization in KB cells. Cell Sci. 106(1):423-430.
23. Weitman, S. D., Lark, R. H., Coney, L. R., Fort, D. W., Frasca, V., Zurawski, V. R. J., and Kamen, B. A. 1992. Distribution of the folate receptor GP 38 in normal and malignant tissues. Cancer Res. 52(12)3396-3401.