Expression of interleukin-6 (IL-6) receptor gene in acute myeloblastic leukemia and response of leukemic cells to exogenous IL-6. A comparative study between cell line cells and corresponding native cells

Growth Factors

Volumn 15, Issue 4, 1998, Pages 243-257

  Säily, Marjaana ^a   Koistinen, Pirjo ^a   Savolainen, Markku ^a   Rantala, Maire ^a   Savolainen, Eeva Riitta ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Acute myeloblastic leukemia; Interleukin 6; Interleukin 6 receptor

Indexed keywords

INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 6; RNA;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; BLAST CELL; CELL CULTURE; CELL PROLIFERATION; CELL SUSPENSION; CLINICAL ARTICLE; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0345164391     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977199809017481     Document Type: Article

References (35)

1. Akashi, K., Harada, M., Shibuya, T., Eto, T., Takamatsu, Y., Teshima, T. and Niho, Y. (1991) Effects of interleukin-4 and interleukin-6 on the proliferation of CD 34+ and CD 34- blasts from acute myelogenous leukemia. Blood, 78, 197-204.
2. Bennett, J. M., Catowsky, D., Daniel, M. T., Flandrin, G., Galton, O. A. G., Gralnick, H. D. and Sultan, C. (1976) Proposals for the classification of acute leukemias. Br J Haematol, 33, 451-458.
3. Buick, R. N., Till, J. E. and McCulloch, E. A. (1977) Colony assay for proliferative blast cells circulating in myeloblastic leukemia. Lancet, i, 862-863.
4. Böyum, A. (1968) Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest, 21(97), 77-89.
5. Carlo-Stella, C., Mangoni, L., Almici, C., Frassoni, F., Fiers, W. and Rizzoli, V. (1990) Growth of CD 34+ acute myeloblastic leukemia colony-forming cells in response to recombinant hematopoietic growth factors. Leukemia, 4, 561-565.
6. Celi, F. S., Zenilman, M. E. and Shuldiner, A. R. (1993) A rapid and versatile method to synthesize internal standards for competetive PCR. Nucleic Acids Res., 21, 1047.
7. Chomczynski, P. and Sacci, N. (1987) Signle-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem., 162, 156-159.
8. Ferrari, S., Grande, A., Manfredini, R., Tagliafico, E., Zucchini, P., Torelli, G. and Torelli, U. (1993) Expression of interleukins 1, 3, 6, stem cell factor and their receptors in acute leukemia blast cells and in normal peripheral lymphocytes and monocytes. Eur J Haematol, 50, 141-148.
9. Förster, E. (1994) An improved general method to generate internal standards for competitive PCR. Bio Tech., 16, 18-20.
10. Garman, R. D., Jacobs, K. A., Clark, S. C. and Raulet, H. D. (1987) B-cell-stimulatory factor 2 (β2 Interferon) functions as a second signal for interleukin 2 production by mature murine T cells. Proc Natl Acad Sci., USA, 84, 7629-7633.
11. Gearing, D. P., Comeau, M. R., Friend, D. J., Gimpel, S. D., Thut, C. J., McGourty, J., Brasher, K. K., King, J. A., Gillis, S., Mosley, B., Ziegler, S. F. and Cosman, D. (1992) The IL-6 signal transducer, gp130: An oncostatin M receptor and affinity converter for the LIF receptor. Science, 255, 1434-1437.
12. Givon, T., Slavin, S., Haran-Ghera, N., Michalevicz, R. and Revel, M. (1992) Antitumor effects of human recombinant interleukin-6 on acute myeloid leukemia in mice and in cell cultures. Blood, 79, 2392-2398.
13. Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T. and Kishimoto, T. (1990) Molecular cloning and expression of an IL-6 signal transducer gp130. Cell, 63, 1149-1157.
14. Hilton, D. J., Hilton, A. A., Raicevic, A., Rakar, S., Harrison-Smith, M., Gough, N. M., Begley, C. G., Metcalf, D., Nicola, N. A. and Willson, T. A. (1994) Cloning of a murine IL-11 receptor α-chain: Requirement for gp130 for high affinity binding and signal transduction. EMBO J, 13, 4765-4775.
15. Hoang, T. and McCulloch, E. A. (1985) Production of leukemic blast growth factor by a human bladder carcinoma cell line. Blood, 66, 748-751.
16. Hoang, T., Haman, A., Goncalves, O., Wong, G. G. and Clark, S. C. (1988) Interleukin-6 enhances growth factor dependent proliferation of blast cells of acute myeloblastic leukemia. Blood, 72, 823-826.
17. Houssiau, F. A., Coulie, P. G., Olive, D. and Van Snick, J. (1988) Synergistic activation of human T cells by interleukin 1 and interleukin 6. Eur J Immunol., 18, 653-656.
18. Ikebuchi, K., Wong, G.-G., Clark, S. C., Ihle, J. N., Hirai, Y. and Ogawa, M. (1987) Interleukin-6 enhancement of interleukin-3 dependent proliferation of multipotential hematopoietic progenitors. Proc Natl Acad Sci. USA, 84, 9035-9039.
19. Inoue, K., Sugiyama, H., Ogawa, H., Yamagami, T., Azuma, T., Oka, Y., Miwa, H., Kita, K., Hiraoka, A., Masaoka, T., Nasu, K., Kyo, T., Dohy, H., Hara, J., Kanamaru, A. and Kishimoto, T. (1994) Expression of the interleukin-6 (IL-6), IL-6 receptor, and gp130 genes in acute leukemia. Blood, 84, 2672-2680.
20. Ip, N. Y., Nye, S. H., Boulton, T. G., Davis, S., Taga, T., Li, Y., Birren, S. J., Yaukawa, K., Kishimoto, T., Anderson, D. J., Stahl, N. and Yancopoulos, G. D. (1992) CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell, 69, 1121-1132.
21. Jernberg, H., Pettersson, M., Kishimoto, T. and Nilsson, K. (1991) Heterogeneity in response to interleukin 6 (IL-6), expression of IL-6 and IL-6 receptor mRNA in a panel of established human multiple myeloma cell lines. Leukemia, 5, 255-265.
22. Kellar, K. L., Hooper, W. C. and Benson, J. M. (1995) MEG01s cells have receptors for and respond to IL-3, IL-6, and SCF. Exp Hematol, 23, 557-564.
23. Koistinen, P., Säily, M., Poromaa, N. and Savolainen, E.-R. (1997) Complex effects of interleukin 6 on clonogenic blast cell growth in acute myeloblastic leukemia. Acta Haematol, 98, 14-21.
24. Leary, A. G., Ikebuchi, K., Hirai, Y., Wong, G. G., Yang, Y.-C, Clark, S. C. and Ogawa, M. (1988) Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hematopoietic stem cells: Comparison with interleukin-1α. Blood, 71, 1759-1763.
25. Lopez, M., Maroc, N., Kerangueven, F., Bardin, F., Courcoul, M., Lavezzi, C., Birg, F. and Mannoni, P. (1991) Coexpression of the genes for interleukin 6 and its receptor without apparent involvement in the proliferation of acute myeloid leukemia cells. Exp Hematol, 19, 797-803.
26. Miyaura, C., Onozaki, K., Akiyama, Y., Taniyama, T., Hirano, T., Kishimoto, T. and Suda, T. (1988) Recombinant human interleukin-6 (B-cell stimulatory factor 2) is a potent inducer of differentiation of mouse myeloid leukemia cells (Ml). FEBS Lett., 234, 17-21.
27. Muraguchi, A., Hirano, T., Tang, B., Matsuda, T., Horii, Y., Nakajima, K. and Kishimoto, T. (1988) The essential role of B cell stimulatory factor-2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med., 167, 332-344.
28. Nakajima-Iijima, S., Hamada, H., Reddy, P. and Kakunaga, T. (1985) Molecular structure of the human cytoplasmic β-actin gene: Interspecies homology of sequences in the introns. Proc Natl Acad Sci. USA, 82, 6133-6137.
29. Okada, M., Kitahara, M., Kishimoto, S., Matsida, T., Hirano, T. and Kishimoto, T. (1988) IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J Immunol., 141, 1543-1549.
30. Pennica, D., Shaw, K. J., Swanson, T. A., Moore, M. W., Shelton, D. L., Zioncheck, K. A., Rosenthal, A., Taga, T., Paoni, N. F. and Wood, W. J. (1995) Cardiotrophin-1: Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem., 270, 10915-10922.
31. Sui, K., Tsuji, K., Tanaka, R., Tajima, S., Muraoka, K., Ebihara, Y., Ikebuchi, K., Yasukawa, K., Taga, T., Kishimoto, T. and Nakahata, T. (1995) gp130 and c-Kit signalings synergize of ex vivo expansion of human primitive hemopoietic progenitor cells. Proc Natl Acad Sci. USA, 92, 2859-2863.
32. Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T. and Kishimoto, T. (1989) Interleukin-6 triggers the association of its receptor with a possible signal transducer gp130. Cell, 58, 573-581.
33. Tosato, G. and Pike, S. E. (1988) Interferon-β 2/interleukin 6 is a co-stimulant for human T lymphocytes. J Immunol., 141, 1556-1562.
34. Yamasaki, K., Taga, T., Hirata, T., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T. and Kishimoto, T. (1988) Cloning and expression of the human interleukin-6 (BSF2/IFNb2) receptor. Science, 241, 825-828.
35. Zhu, Y.-M., Bradbury, D. A., Keith, F. J. and Russel, N. (1994) Absence of retinoblastoma protein expression results in autocrine production of interleukin-6 and promotes the autonomous growth of acute myeloid leukemia blast cells. Leukemia, 8, 1982-1988.