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6b,9
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22
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0344110662
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note
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4 ortho-, and meto-dichlorobenzene dicarbonyl 2,6-dimethylphenylisonitrile complexes reacted with alkoxydes, carbanions, indole, and acetone oxime anions under very mild conditions (DMF, 20-35°C).
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0342650982
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0344973153
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note
-
Resin 3a was also reacted with benzylamine, but no reaction product was isolated; phenols were not tried.
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-
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25
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0344973148
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note
-
We did not try a second nucleophilic addition on resin-bound monopyrrolidine adducts 5c and 6c, but from in-solution reactions of the corresponding dicarbonylphenylisonitrile complexes, we found that ortho adduct did not react with MeONa also heating up to 80°C, whereas the meta adduct only reacted with MeONa at 60°C, but no reaction occurred heating with indole anion or pyrrolidine up to 80°C.
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