Fluoride metabolism in smokers and non-smokers following enflurane anaesthesia

British Journal of Anaesthesia

Volumn 91, Issue 6, 2003, Pages 800-804

  Laisalmi, Merja ^a,b   Soikkeli, A ^a   Kokki, H ^b   Markkanen, H ^a   Yli Hankala, A ^c   Rosenberg, P ^a   Lindgren, L ^c  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Anaesthetics volatile; Complications; Enflurane; Enzymes; Inhibition; Inorganic fluoride; Metabolism; Protein; Smokers; Trypsin; 2 microglobulin

Indexed keywords

ANESTHETIC AGENT; APROTININ; BETA 2 MICROGLOBULIN; CREATININE; DISULFIRAM; ENFLURANE; FLUORIDE; ISONIAZID; OXYGEN; TOBACCO SMOKE;

ADULT; AIR; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG METABOLISM; ELECTIVE SURGERY; FEMALE; GYNECOLOGIC SURGERY; HUMAN; HUMAN EXPERIMENT; KIDNEY DYSFUNCTION; KIDNEY INJURY; MINIMUM LUNG ALVEOLUS CONCENTRATION; NEPHROTOXICITY; NORMAL HUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0345099554     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeg272     Document Type: Article

References (23)

1. Cousins MJ, Mazze RI. Methoxyflurane nephrotoxicity: a study of dose response in man. JAMA 1973; 225: 1611-6
2. Eichhorn JH, Hedley-Whyte J, Steinman TI, Kaufmann JM, Laasbert JH. Renal failure following enflurane anesthesia. Anesthesiology 1976; 45: 557-60
3. Mazze RI, Woodruff RE, Heerdt ME. Isoniazid-induced enflurane defluorination in humans. Anesthesiology 1982; 57: 5-8
4. Kharasch ED, Thummel KE, Mautz D, Bosse S. Clinical enflurane metabolism by cytochrome P450 2E1. Clin Pharmacol Ther 1994; 55: 434-40
5. Motuz DJ, Watson WA, Barlow JC, Velasquez NV, Schentag JJ. The increase in urinary alanine aminopeptidase excretion associated with enflurane anesthesia is increased further by aminoglycosides. Anesth Analg 1988; 67: 770-4
6. Uutela A, Koskinen S. Health and Functional Capacity in Finland Baseline Results of the Health 2000 Examination Survey, 1st edn. Publication B3/2002. Helsinki: Finnish National Public Health Institute, 2002
7. VanFleet TR, Bombick DW, Coulombe RA Jr. Inhibition of human cytochrome P450 2E?1 by nicotine, cotine, and aqueous cigarette tar extract in vitro. Toxicol Sci 2001; 64: 185-91
8. Kharasch ED, Thummel KE. Identification of cytochrome P450 2E1 as the predominant enzyme catalysing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane. Anesthesiology 1993; 79: 795-807
9. Jusko WJ. Influence of cigarette smoking on drug metabolism in man. Drug Metab Rev 1979; 9: 221-36
10. Vähäkangas K, Pelkonen O, Sotaniemi E. Cigarette smoking and drug metabolism. Clin Pharmacol Ther 1983; 33: 375-80
11. Vaughan DP, Beckett AH, Robbie DS. The influence of smoking on the intersubject variation in pentazocine elimination. Br J Clin Pharmacol 1976; 3: 279-83
12. Eto K, Gomita Y, Furuno K, Mimaki Y, Okazaki M, Araki Y. Influences of long term smoke exposure on pharmacokinetics of theophylline, and liver microsomal enzymes in rats. Drug Metabol Drug Interact 1992; 10: 265-77
13. World Medical Association. Declaration of Helsinki: ethical principles for medical research involving human subjects. 52nd World Medical Association, General Assembly, Edinburgh, October 2000
14. 2-microglobulin as marker of GFR. Ren Fail 2001; 23: 419-29
15. Tramonti G, Ferdeghini M, Donadio C, et al. Tumor associated trypsin inhibitor (TATI) and renal function. Kidney Int Suppl 1997; 63: S179-81
16. Wellwood JM, Ellis BG, Price RG, et al. Urinary N-acetyl-β-D-glucosaminidase activities in patients with renal disease. Br Med J 1975; 3: 408-11
17. Fry BW, Taves DR. Serum fluoride analysis with the fluoride electrode. J Lab Clin Med 1970; 75: 1020-5
18. Mazze RI, Calverley RK, Smith NT. Inorganic fluoride nephrotoxicity: prolonged enflurane and halothane anesthesia in volunteers. Anesthesiology 1977; 46: 265-71
19. Baden JM, Rice SA. Metabolism and toxicity of inhaled anesthetics. In: Miller RD (ed.). Anesthesia. Philadelphia: Churchill Livingstone, 2000; 147-73
20. Orhan H, Vermeulen NPE, Sahin G, Commandeur JNM. Characterization of thioether compounds formed from alkaline degradation products of enflurane. Anesthesiology 2001; 95: 165-75
21. Higuchi H, Sumikura H, Sumita S, et al. Renal function in patients with high serum fluoride concentrations after prolonged sevoflurane anesthesia. Anesthesiology 1995; 83: 449-58
22. 2-microglobulin in multiple myeloma. Life Sci 1991; 49: 435-8
23. Medl M, Ogris E, Peters-Engl C, Leodolter S. TATI (tumour-associated trypsin inhibitor) as a marker of ovarian cancer. Br J Cancer 1995; 71: 1051-4