Inadvertent intrathecal injection of tramadol

British Journal of Anaesthesia

Volumn 91, Issue 6, 2003, Pages 918-920

  Barrett, N A ^a   Sundaraj, S R ^a  

^a NEPEAN HOSPITAL   (Australia)

Author keywords

Analgesic opioids, tramadol; Complications, cancer; Complications, intrathecal catheters

Indexed keywords

BACLOFEN; BUPIVACAINE; FENTANYL; GABAPENTIN; KETAMINE; MIDAZOLAM; MORPHINE; PHENOBARBITAL; TRAMADOL;

ADULT; ANESTHESIA COMPLICATION; ARTICLE; BACKACHE; BONE METASTASIS; BONE PAIN; CANCER PAIN; CANCER PALLIATIVE THERAPY; CASE REPORT; CLINICAL FEATURE; DIAPHORESIS; FEMALE; HUMAN; HYPOTENSION; MYOCLONUS; NEUROPATHIC PAIN; OUTCOMES RESEARCH; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0345099547     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeg265     Document Type: Article

References (22)

1. Baraka A, Jabbour S, Ghabesh M. A comparison of epidural tramadol and epidural morphine for postoperative analgesia. Can J Anaesth 1993; 40: 308-13
2. Delilkan A, Vijayan R. Epidural tramadol for postoperative pain relief. Anaesthesia 1993; 48: 328-31
3. Radbruch L, Grond S, Lehmann K. A risk-benefit assessment of tramadol in the management of pain. Drug Saf 1996; 15: 8-29
4. Ozcengiz D, Gunduz M, Ozbek H, Isik G. Comparison of caudal morphine and tramadol for postoperative pain control in children undergoing inguinal herniorrhaphy. Paediatr Anaesth 2001; 11: 459-64
5. Friderichs E, Reimann W, Shank R, Codd E, Vaught J. Opioid and nonopioid components contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther 1992; 260: 275-85
6. Dhasmana K, Banerjee A, Rating W, Erdmann W. Analgesic effect of tramadol in the rat. Acta Pharmacol Sin 1989; 10: 289-94
7. Bernatzky G, Jurna I. Intrathecal injection of codeine, buprenorphine, tilidine, tramadol and nefopam depress the tailflick response in rats. Eur J Pharmacol 1985; 120: 75-80
8. Lubenow T. Analgesic, hemodynamic and respiratory responses to intrathecal tramadol in dogs. Anaesthesiology 1995; 83: a822
9. Lange-Asschenfeldt C, Weigmann H, Hiemke C, Mann K. Serotonin syndrome as a result of fluoxetine in a patient with tramadol abuse: plasma level-correlated symptomatology. J Clin Psychopharmacol 2002; 22: 440-1
10. Spiller H, Gorman S, Villalobos D, et al. Prospective multicenter evaluation of tramadol exposure. J Toxicol Clin Toxicol 1997; 35: 361-4
11. Mason B, Blackburn K. Possible serotonin syndrome associated with tramadol and sertraline coadministration. Ann Psychopharmacother 1997; 31: 175-7
12. Gardner J, Blough D, Drinkard C, et al. Tramadol and seizures: a surveillance study in a managed care population. Pharmacotherapy 2000; 20: 1423-31
13. Lane R, Baldwin D. Selective serotonin reuptake inhibitor-induced serotonin syndrome: review. J Clin Psychopharmacol 1997; 17: 208-21
14. Potschka H, Friderichs E, Loscher W. Anticonvulsant and proconvulsant effects of tramadol, its enantiomers and its MI metabolite in the rat kindling model of epilepsy. Br J Pharmacolol 2000; 131: 203-12
15. Smith M. Neuroexcitatory effects of morphine and hydromorphone: evidence implicating the 3-glucuronide metabolites. Clin Exp Pharmacol Physiol 2000; 27: 524-8
16. Sarhill N, Davis M, Walsh D, Nouneh C. Methadone-induced myoclonus in advanced cancer. Am J Hospice Palliat Care 2001; 18: 51-3
17. Wagemans M, Bakker E, Zuurmond W, et al. Intrathecal administration of high-dose morphine solutions decreases the pH of cerebrospinal fluid. Pain 1995; 61: 55-9
18. Hew C, Cyna A, Simmons S. Avoiding inadvertent epidural injection of drugs intended for non-epidural use. Anaesth Intens Care 2003; 31: 44-9
19. Runciman W, Sellen A, Webb R, et al. Errors, incidents and accidents in anaesthetic practice. Anaesth Intens Care 1993; 21: 506-19
20. Laws D. The time has come for non-interchangeability of spinal and epidural equipment with intravascular access ports. Br J Anaesth 2001; 86: 903
21. Lanigan C. Safer epidural and spinal connectors. Anaesthesia 2002; 57: 567-71
22. Cyna A, Simmons S, Osborn K, Andrew M. Fatal epidural infusion - call for a system wide change. Anaesth Intens Care 2002; 30: 99-100