Distribution of the HLA class I allele in chronic hepatitis C and its association with serum ALT level in chronic hepatitis C

Tohoku Journal of Experimental Medicine

Volumn 201, Issue 2, 2003, Pages 109-117

  Kondo, Yasuteru ^e   Kobayashi, Koju ^a,e   Kobayashi, Tomoo ^b   Shiina, Masaaki ^c   Ueno, Yoshiyuki ^e   Satoh, Takaomi ^d   Shimosegawa, Tooru ^e  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Furukawa City Hospital   (Japan)

^c SENDAI CITY MEDICAL CENTER   (Japan)

^d Sendai Shakaihoken Hospital   (Japan)

^e TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cellular immune response; CTL; HLA class I allele; HLA A2; Japanese individuals

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; CD8 ANTIGEN; HEPATITIS C ANTIGEN; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; HLA B51 ANTIGEN; HLA C ANTIGEN;

ADULT; ALLELE; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE ACTIVITY; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; HEPATITIS C; HEPATITIS C VIRUS; HEREDITY; HOMOZYGOSITY; HUMAN; IMMUNE RESPONSE; JAPAN; LYMPHOCYTE FUNCTION; MAJOR CLINICAL STUDY; MALE; TREATMENT OUTCOME;

ADULT; AGED; ALANINE TRANSAMINASE; CHRONIC DISEASE; FEMALE; GENE FREQUENCY; GENES, MHC CLASS I; GENOTYPE; HEPATITIS C; HUMANS; JAPAN; MALE; MIDDLE AGED;

EID: 0345099440     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.201.109     Document Type: Article

References (22)

1. Boyington, J.C. & Sun, P.D. (2002) A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors. Mol. Immunol., 38, 1007-1021.
2. Carrington, M., Nelson, G.W., Martin, M.P., Kissner, T., Vlahov, D., Goedert, J.J., Kaslow, R., Buchbinder, S., Hoots, K. & O'Brien, S.J. (1999) HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage. Science, 283, 1748-1752.
3. Chang, K.M., Thimme, R., Melpolder, J.J., Oldach, D., Pemberton, J., Moorhead-Loudis, J., McHutchison, J.G., Alter, H.J. & Chisari, F.V. (2001) Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection. Hepatology, 33, 267-276.
4. Dianzani, F. (1993) Biological basis for the clinical use of interferon. Gut, 34, Suppl. 2, S74-S76.
5. Doherty, P.C. & Zinkernagel, R.M. (1975) Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex. Nature, 256, 50-52.
6. Germain, R.N. (1994) MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell, 76, 287-299.
7. Hashimoto, M., Kinoshita, T., Yamasaki, M., Tanaka, H., Imanishi, T., Ihara, H., Ichikawa, Y. & Fukunishi, T. (1994) Gene frequencies and haplotypic associations within the HLA region in 916 unrelated Japanese individuals. Tissue Antigens, 44, 166-173.
8. Hiroishi, K., Kita, H., Kojima, M., Okamoto, H., Moriyama, T., Kaneko, T., Ishikawa, T., Ohnishi, S., Aikawa, T., Tanaka, N., Yazaki, Y., Mitamura, K. & Imawari, M. (1997) Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection. Hepatology, 25, 705-712.
9. Hoofnagle, J.H., Di Bisceglie, A.M. & Shindo, M. (1993) Antiviral therapy of hepatitis C-present and future. J. Hepatol., 17, Suppl. 3, S130-S136.
10. Kuzushita, N., Hayashi, N., Katayama, K., Hiramatsu, N., Yasumaru, M., Murata, H., Shimizu, Y., Yamazaki, T., Fushimi, H., Kotoh, K., Kasahara, A., Fusamoto, H. & Kamada, T. (1996) Increased frequency of HLA DR13 in hepatitis C virus carriers with persistently normal ALT levels. J. Med. Virol., 48, 1-7.
11. Kuzushita, N., Hayashi, N., Moribe, T., Katayama, K., Kanto, T., Nakatani, S., Kaneshige, T., Tatsumi, T., Ito, A., Mochizuki, K., Sasaki, Y., Kasahara, A. & Hori, M. (1998) Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus. Hepatology, 27, 240-244.
12. MacDonald, K.S., Embree, J.E., Nagelkerke, N.J., Castillo, J., Ramhadin, S., Njenga, S., Oyug, J., Ndinya-Achola, J., Barber, B.H., Bwayo, J.J. & Plummer, F.A. (2001) The HLA A2/6802 supertype is associated with reduced risk of perinatal human immunodeficiency virus type 1 transmission. J. Infect. Dis., 183, 503-506.
13. Poynard, T., Marcellin, P., Bissery, A., Myers, R.P., Moussalli, J., Degos, F., Dhumeaux, D., Riachi, G., Bronowicki, J.P., Brissot, P., Buffet, C., Serfaty, L., Naveau, S., Sogni, P., Beaugrand, M., Gayno, S., Larrey, D., Samuel, D., Eugene, C., Pol, S., Bedossa, P., Daurat, V. & Chaumet-Riffaud, P.; GER-CYT-RIBANON group. (2003) Reinforced interferon alpha-2b and ribavirin is more effective than standard combination therapy in the retreatment of chronic hepatitis C previously nonresponsive to interferon: a randomized trial. J. Viral. Hepat., 10, 197-204.
14. Rehermann, B. (1999) Cellular immune response to the hepatitis C virus. J. Viral. Hepat., 6, Suppl. 1, 31-35.
15. Rehermann, B. (2000) Interaction between the hepatitis C virus and the immune system. Semin. Liver Dis., 20, 127-141.
16. Renou, C., Halfon, P., Pol, S., Cacoub, P., Jouve, E., Bronowicki, J.P., Arpurt, J.P., Rifflet, H., Picon, M., Causse, X., Canva, V., Denis, J., Tran, A., Bourliere, M., Ouzan, D., Pariente, A., Dantin, S., Alric, L., Cartier, V., Reville, M., Caillat-Zucman, S. (2002) Histological features and HLA class II alleles in hepatitis C virus chronically infected patients with persistently normal alanine aminotransferase levels. Gut, 51, 585-590.
17. Romero-Gomez, M., Gonzalez-Escribano, M.F., Torres, B., Barroso, N., Montes-Cano, M.A., Sanchez-Munoz, D., Nunez-Roldan, A. & Aguilar-Reina, J. (2003) HLA class I B44 is associated with sustained response to interferon + ribavirin therapy in patients with chronic hepatitis C. Am. J. Gastroenterol., 98, 1621-1626.
18. Stephens, H.A., Klaythong, R., Sirikong, M., Vaughn, D.W., Green, S., Kalayanarooj, S., Endy, T.P., Libraty, D.H., Nisalak, A., Innis, B.L., Rothman, A.L., Ennis, F.A. & Chandanayingyong, D. (2002) HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens., 60, 309-318.
19. Su, A.I., Pezacki, J.P., Wodicka, L., Brideau, A.D., Supekova, L., Thimme, R., Wieland, S., Bukh, J., Purcell, R.H., Schultz, P.G. & Chisari, F.V. (2002) Genomic analysis of the host response to hepatitis C virus infection. Proc. Natl. Acad. Sci. USA, 99, 15669-15674.
20. Takada, N., Takase, S., Takada, A. & Date, T. (1993) Differences in the hepatitis C virus genotypes in different countries. J. Hepatol., 17, 277-283.
21. Thio, C.L., Gao, X., Goedert, J.J., Vlahov, D., Nelson, K.E., Hilgartner, M.W., O'Brien, S.J., Karacki, P., Astemborski, J., Carrington, M. & Thomas, D.L. (2002) HLA-Cw * 04 and hepatitis C virus persistence. J. Virol., 76, 4792-4797.
22. Vejbaesya, S., Songsivilai, S., Tanwandee, T., Rachaibun, S., Chantangpol, R. & Dharakul, T. (2000) HLA association with hepatitis C virus infection. Hum. Immunol., 61, 348-353.