Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans

Toxicological Sciences

Volumn 47, Issue 2, 1999, Pages 144-150

  Völkel, Wolfgang ^a   Wolf, Nataly ^a   Derelanko, Michael ^b   Dekant, Wolfgang ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b HONEYWELL   (United States)

Author keywords

Human; Mouse; Nitronates; Oximes; Rat; Sex specific tumorigenicity

Indexed keywords

3 METHYLCHOLANTHRENE; COUMARIN; CYTOCHROME P450; DIETHYLDITHIOCARBAMIC ACID; ENZYME INHIBITOR; NITRO DERIVATIVE; OCTYLAMINE; OXIME; PHENOBARBITAL; PYRIDINE;

ADULT; AGED; ANIMAL MODEL; ARTICLE; BIOTRANSFORMATION; CARCINOGENICITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; LIVER MICROSOME; LIVER TUMOR; MALE; NONHUMAN; OXIDATION; SEX DIFFERENCE;

ANIMALS; BUTANONES; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; MICE; MICROSOMES, LIVER; NITROPARAFFINS; OXIDATION-REDUCTION; OXIMES; RATS; RATS, WISTAR; SEX CHARACTERISTICS;

EID: 0345085694     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/47.2.144     Document Type: Article

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