Chemical modifications to study mutations that affect the ability of the general base (E268) to function in human liver mitochondrial aldehyde dehydrogenase

Chemico-Biological Interactions

Volumn 143-144, Issue , 2003, Pages 85-91

  Wei, Baoxian ^a   Mays, Dennis C ^b   Lipsky, James J ^b   Weiner, Henry ^a  

^a PURDUE UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Aldehyde dehydrogenase; Asian variant of ALDH; Chemical modifications; Disulfiram analogs; General base

Indexed keywords

ALDEHYDE; ALDEHYDE DEHYDROGENASE; CYSTEINE; DISULFIRAM; NICOTINAMIDE ADENINE DINUCLEOTIDE; S METHYL N,N DIETHYLTHIOCARBAMOYLSULFOXIDE; SULFOXIDE; UNCLASSIFIED DRUG; WATER;

BINDING AFFINITY; CHEMICAL MODIFICATION; CONFERENCE PAPER; ENZYME ANALYSIS; ENZYME SPECIFICITY; HYDROLYSIS; METABOLITE; MITOCHONDRION; MUTATION; OXIDATION;

ALDEHYDE DEHYDROGENASE; DITIOCARB; HUMANS; MITOCHONDRIA, LIVER; MUTATION; NAD;

EID: 0345073750     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00177-1     Document Type: Conference Paper

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