One active C1r subunit is sufficient for the activity of the complement C1 complex: Stabilization of C1r in the zymogen form by point mutations

Journal of Immunology

Volumn 162, Issue 2, 1999, Pages 1108-1112

  Dobó, József ^a   Gál, Péter ^a   Szilágyi, Katalin ^a   Cseh, Sándor ^a   Lörincz, Zsolt ^a   Schumaker, Verne N ^b   Závodszky, Péter ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; COMPLEMENT COMPONENT C1; ENZYME PRECURSOR; ISOLEUCINE; LYSINE;

ANIMAL CELL; ARTICLE; CATALYSIS; COMPLEMENT ACTIVATION; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME SUBUNIT; HEMOLYSIS; MEMBRANE STABILIZATION; MOLECULAR CLONING; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING;

ANIMALS; BACULOVIRIDAE; BLOTTING, WESTERN; COMPLEMENT C1R; COMPLEMENT HEMOLYTIC ACTIVITY ASSAY; COMPLEMENT PATHWAY, CLASSICAL; DIMERIZATION; DNA, COMPLEMENTARY; ENZYME PRECURSORS; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEMOLYSIS; HUMANS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; SPODOPTERA;

EID: 0345059840     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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