Presence of uterine pinopodes at the embryo-endometrial interface during human implantation in vitro

Human Reproduction

Volumn 14, Issue 2, 1999, Pages 515-520

  Bentin Ley, U ^a   Sjogren A ^b   Nilsson, L ^c   Hamberger, L ^b   Larsen, J F ^a   Horn, T ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Embryo; Human; Implantation; In vitro; Morphology

Indexed keywords

ARTICLE; BLASTOCYST; CELL ADHESION; CELL CULTURE; CELL STRUCTURE; EMBRYO; ENDOMETRIUM; ENDOMETRIUM BIOPSY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMPLANTATION; IN VITRO STUDY; MICROVILLUS; NIDATION; PINOPODE; PSEUDOPODIUM; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; UTERUS;

EID: 0345040180     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/14.2.515     Document Type: Article

References (47)

1. Bentin-Ley, U., Petersen, B., Lindenberg, S. et al. (1994) Isolation and culture of human endometrial cells in a three dimensional cell culture system. J. Reprod. Fert., 101, 327-332.
2. Bentin-Ley, U., Lindenberg, S., Horn, T. et al. (1995) Ultrastructure of endometrial epithelial cells in a three-dimensional cell culture system for human implantation studies. J. Assist. Reprod. Genet., 12, 632-638.
3. Davis, M.C. and Rozenwaks, Z. (1993) Preparation of the endometrium for egg donation. J. Assist. Reprod. Genet., 10, 457-459.
4. Denker, H-W. (1993) Implantation: a cell biological paradox. J. Exp. Zool., 266, 541-558.
5. Edwards, R.G. (1988) Human uterine endocrinology, and the implantation window. Ann. N. Y. Acad. Sci., 541, 445-454.
6. Edwards, R.G. (1995) Clinical approaches to increasing uterine receptivity during human implantation. Hum. Reprod., 10 (Suppl. 2), 60-66.
7. Edwards, R.G., Marcos, S., Macnamee, M. et al. (1991) High fecundity in amenorrhoeic women in embryo-transfer programmes. Lancet. 338, 292-294.
8. Enders, A.E. and Nelson, D.M. (1973) Pinocytotic activity in the uterus of the rat. Am. J. Anat., 138, 277-300.
9. Enders, A.C., Liu, I.K., Mead, R.A. et al. (1995) Active and passive morphological interactions of trophoblast and endometrium during early implantation. In Dey, S.K. (ed.), Molecular and Cellular Aspects of Periimplantation Processes. Springer Verlag, Berlin, pp. 168-182.
10. Ferenczy, A. (1977) Surface ultrastructural response of the human uterine lining epithelium to hormonal environment: a scanning electron microscopic study. Acta Cytol., 21, 566-572.
11. Ferenczy, A. and Richart, R.M. (1973) Scanning and transmission electron microscopy of the human endometrial surface epithelium. J. Clin. Endocr. Metab., 36, 999-1008.
12. Ferenczy, A., Richart, R.M., Agate, F.J. et al. (1972) Scanning electron microscopy of the human endometrial surface epithelium. Fertil. Steril., 23, 515-521.
13. Hafez, E.S.E. and Ludwig, H. (1977) Scanning electron microscopy of the endometrium. In Wynn, R.M. (ed.), Biology of the Uterus. Plenum Press, New York, pp. 309-340.
14. Johannisson, E. and Nilsson, L. (1972) Scanning electron microscopy of the human endometrium. Fertil. Steril., 23, 613-625.
15. Kolb, B.A., Najmabadi, S. and Paulson, R.J. (1997) Ultrastructural characteristics of the luteal phase endometrium in patients undergoing controlled ovarian hyperstimulation. Fertil. Steril., 67, 625-630.
16. Lessey, B.A. (1997) Integrins and the endometrium: new markers of uterine receptivity. Ann. N. Y. Acad. Sci., 828, 111-122.
17. Lessey, B.A., Damjanovich, L., Coutifaris, C. et al. (1992) Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. J. Clin. Invest., 90, 188-195.
18. Lessey, B.A., Yeh, I., Castelbaum. A.J. et al. (1996) Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation. Fertil. Steril., 65, 477-483.
19. Lindenberg, S. (1991) Ultrastructure in human implantation: transmission and scanning electron microscopy. Baillières Clin. Obstet. Gynaecol., 5, 1-12.
20. Lopata, A. (1996) Blastocyst - endometrial interaction: an appraisal of some old and new ideas. Mol. Hum. Reprod., 2, 519-525.
21. Massai, M.R., Bergeron, C., Martel, D. et al. (1993) Physiological oestradiol and progesterone replacement cycles in women with ovarian failure: a model to study endometrial maturation and sex steroid receptor regulation by exogenous hormones. Hum. Reprod., 8, 1828-1834.
22. Martel, D., Malet, C., Gautray, J.P. et al. (1981) Surface changes of the luminal uterine epithelium during the human menstrual cycle: a scanning electron microscopic study. In de Brux. J. and Gautrey, J.P. (eds). The Endometrium: Hormonal Implants. Plenum Press. New York, pp. 15-29.
23. Martel, D., Frydman, R., Glissant, M. et al. (1987) Scanning electron microscopy of postovulatory human endometrium in spontaneous cycles stimulated by hormone treatment. J. Endocr., 114, 319-324.
24. Martel, D., Monier, M.N., Roche, D. et al. (1991) Hormonal dependence of pinopode formation at the uterine luminal surface. Hum. Reprod., 6, 597-603.
25. Meyer, W.R., Castelbaum, A.J., Somkuti, S. et al. (1997) Hydrosalpinges adversely affect markers of endometrial receptivity. Hum. Reprod., 12, 1393-1398.
26. Navot, D., Scott, R.T., Droesch, K. et al. (1991) The window of embryo transfer and the efficiency of human conception in vitro. Fertil. Steril., 55, 114-118.
27. Nilsson, O. and Nygren, K-G. (1974) Ultrastructure of human uterine epithelium at the time of implantation after postovulatory administration of norethindrone. Upsala J. Med. Sci., 79, 65-71.
28. Nikas, G., Drakakis, P., Loutradis, D. et al. (1995) Uterine pinopodes as markers of the 'nidation window' in cycling women receiving exogenous oestradiol and progesterone. Hum. Reprod., 10, 1208-1213.
29. Nikas, G., Develioglu, O.H., Toner, J.P. et al. (1999) Endometrial pinopodes indicate a shift in the window of receptivity in IVF cycles. Hum. Reprod., (in press).
30. Paulson, R.J., Sauer, M.V. and Lobo, R.A. (1990) Factors, affecting embryo implantation after human in vitro fertilization: a hypothesis. Am. J. Obstet. Gynecol., 163, 2020-2023.
31. Paulson, R.J., Sauer, M.V. and Lobo, R.A. (1997) Potential enhancement of endometrial receptivity in cycles using controlled ovarian hyperstimulation with antiprogestins: a hypothesis. Fertil. Steril., 67, 321-325.
32. Pellicer, A., Valbuena, D., Cano, F. et al. (1996) Lower implantation rates in high responders: evidence for an altered endocrine milieu during the preimplantation period. Fertil. Steril., 96, 1190-1195.
33. Psychoyos, A. (1976) Hormonal control of uterine receptivity for nidation. J. Reprod. Fertil., 25 (Suppl.), 17-28.
34. Psychoyos, A. (1986) Uterine receptivity for nidation. Ann. N. Y. Acad. Sci., 476, 36-42.
35. Psychoyos, A. and Martel, D. (1985) Embryo-endometrial interactions and implantation. In Edwards, R.G., Purdy, J.M. and Steptoe, P.C. (eds), Implantation of the Human Embryo. Academic Press, London, p. 195.
36. Psychoyos, A. and Nikas, G. (1994) Uterine pinopodes as markers of uterine receptivity. Assist. Reprod. Rev., 4, 26-32.
37. Rosenwaks, Z. (1987) Donor eggs: their application in modern reproductive technologies. Fertil. Steril., 47, 895-909.
38. Simón, C., Piquette, G.N., Frances, A. et al. (1993) Localization of interleukin-1 type I receptor and interleukin-1β in human endometrium throughout the menstrual cycle. J. Clin. Endocrinol. Metab., 77, 549-555.
39. Simón, C., Cano, F., Valbuena, D. et al. (1995a) Clinical evidence for a detrimental effect on uterine receptivity of high serum oestradiol levels in high and normal responder patients. Hum. Reprod., 10, 2432-2437.
40. Simón, C., Frances, A., Lee, B.Y. et al. (1995b) Immunohistochemical localization, identification and regulation of the interleukin-1 receptor antagonist in the human endometrium. Hum. Reprod., 10, 2472-2477.
41. Simón, C., Gimeno, M.J., Mercader, A. et al. (1997) Embryonic regulation of integrine β3, α4 and α1 in human endometrial epithelial cells in vitro. J. Clin. Endocrinol. Metab., 82, 2607-2616.
42. Simón, C., Garcia Velasco, J., Valbuena, D. et al. (1998) Increased uterine receptivity by decreasing estradiol levels during the preimplantation period in high responder patients by using an FSH step-down regimen. Fertil. Steril., 70, 234-239.
43. Sundström, P., Nilsson, O. and Liedholm, P. (1983) Scanning electron microscopy of human preimplantation endometrium on normal and clomiphene/human chorionic gonadotrophin-stimulated cycles. Fertil. Steril., 40, 642-647.
44. Thie, M., Fuchs, P. and Denker, H-W. (1996) Epithelial cell polarity and embryo implantation in mammals. Int. J. Dev. Biol., 40, 389-393.
45. Thie, M., Herter, P., Pommerenke, H. et al. (1997) Adhesiveness of the free surface of a human endometrial monolayer for trophoblast as related to actin cytoskeleton. Mol. Hum. Reprod., 3, 275-283.
46. Vokaer, R. and Leroy, F. (1962) Experimental study of local factors in the process of implantation in the rat. Am. J. Obstet. Gynecol., 83, 141-148.
47. Yoshinaga, K. (1988) Uterine receptivity for blastocyst implantation. Ann. N. Y. Acad. Sci., 541, 424-431.