Management of acute spinal cord injury with corticosteroids;Zur gabe von kortikosteroiden nach akuter spinaler traumatisierung - Mitteilung des wissenschaftlichen arbeitskreises neuroanasthesie der DGAI

Anasthesiologie und Intensivmedizin

Volumn 40, Issue 10, 1999, Pages 716-726

  Himmelseher, S ^a   Buttner J ^b   Baethmann, A ^b   Piek, J ^b   Unterberg, A W ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NONE

Author keywords

Adrenal cortex hormones; Methylprednisolone; Outcome assessment (Health care); Spinal cord injuries

Indexed keywords

CORTICOSTEROID; METHYLPREDNISOLONE; PREDNISOLONE;

ARTICLE; CORTICOSTEROID THERAPY; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG RESPONSE; DRUG SAFETY; HUMAN; PNEUMONIA; SEPSIS; SPINAL CORD INJURY; TREATMENT OUTCOME;

EID: 0345035264     PISSN: 01705334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Anderson D, Hall E: Pathophysiology of spinal cord trauma. Ann Emerg Med 22 (1993) 987-992
2. Bracken MB, Collins WF, Freeman D: Efficacy of methylprednisolone in acute spinal cord injury. JAMA 251 (1984) 45-52
3. Bracken MB, Shepard MJ, Hellenbrand KG et al: Methylprednisolone and neurological function one year after spinal cord injury. J Neurosurg 63 (1985) 704-713
4. Bracken MB, Shepard MJ, Collins WF, et al: A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury. N Engl J Med 322 (1990) 1405-1411
5. Bracken MB, Shepard MJ, Collins WF, et al: Methylprednisolone or naloxone treatment after acute spinal cord injury:1-year follow-up data. J Neurosurg 76 (1992a) 23-31
6. Bracken MB: Pharmacological treatment of acute spinal cord injury: current status and future prospects. Paraplegia 30 (1992b) 102-107
7. Bracken MB, Holford TR: Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS-2. J Neurosurg 79 (1993) 500-507
8. Bracken MB, Shepard MJ, Holford TR et al: Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. JAMA 277 (1997) 1597-1604
9. Bracken MB, Shepard MJ, Holford TR et al: Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third national acute spinal cord injury randomized controlled trial. J Neurosurg 89 (1998) 699-706
10. Braughler JM, Hall ED: Effects of multi-dose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism. J Neurosurg 61 (1984) 290-295
11. Buttgereit F, Dimmeler S, Neugebauer E, Burmester GR: Wirkmechanismen der hochdosierten Glucocorticoid-therapie. Dtsch Med Wschr 121 (1996) 248-252
12. Chiles BW 3rd, Cooper PR: Acute spinal injury. N Engl J Med 34 (1996) 514-520
13. Dietz V: Locomotor pattern in paraplegic patients: training effects and recovery of spinal cord function. Spinal Cord 36 (1998) 380-390
14. Ducker TB, Zeidman SM: Spinal cord injury. Role of steroid therapy. Spine 20 (1994) 2281-2287
15. Frankel HL, Hancock DO, Hyslop G, Melzak J, Michaelis LS, Ungar GH, Vernon JD, Walsh JJ: The value of postural reduction in the inital management of closed injuries to the spine with paraplegia and tetraplegia. Paraplegia 7 (1969) 179-192
16. Gabler C, Maier R: Hochdosierte Methylprednisolon-therapie bei Rückenmarkstrauma. Unfallchirurgie 21 (1995) 20-29
17. Galandiuk S, Raque G, Appel S, Polk HC: The two-edged sword of large-dose steroids for spinal cord trauma. Ann Surg 218 (1993) 419-426
18. George ER, Scholten DJ, Büchler M, Jordan-Tibbs J, Mattice C, Albrecht RM: Failure of methylprednisolone to improve the outcome of spinal cord injuries. Am Surg 61 (1995) 659-663
19. Gerhart KA, Johnson RL, Menconi J, Hoffman RE, Lammertse DP: Utilization and effectiveness of methylprednisolone in a population-based sample of spinal cord injured persons. Paraplegia 33 (1995) 316-321
20. Gerndt SJ, Rodriguez JL, Pawlik JW, Taheri PA, Wahl WL, Michaels AJ, Papadopoulos SM: Consequences of high-dose steroid therapy for acute spinal cord injury. J Trauma 42 (1997) 279-284
21. Green B, Kahn T, Klose K: A comparative study of steroid therapy in acute experimental spinal cord injury. Surg Neurol 13 (1980) 91-97
22. Hall ED: The neuroprotective pharmacology of methylprednisolone. J Neurosurg 76 (1992) 13-22
23. Hall ED: Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury. Cell Mol Neurobiol 13 (1993) 415-432
24. Hanigan WC, Anderson RJ: Commentary on NASCIS-2. Spinal Disord 5 (1992) 125-131
25. Hoerlein B, Redding R, Hoff E, Ja M: Evaluation of naloxone, crocetin, thyrotropin releasing hormone, methylprednisolone, partial myelotomy, and hemilaminectomy in the treatment of acute spinal cord trauma. J Am Animal Hosp Assoc 21 (1984) 67-77
26. Holford TR, Bracken MB: A model for estimating level and net severity of spinal cord injuries. Stat Med 2 (1992) 1171-1186
27. Leary W: Treatment is said to reduce disability from spinal injury. New York Times, March 31, 1990
28. Maynard FM, Bracken MB, Creasey G et al: International standards for neurological and functional classification of spinal cord injury. American Spinal Injury Association. Spinal Cord 35 (1997) 266-274
29. Means E, Anderson D, Waters T, Kalaf L: Effect of methylprednisolone in compression trauma to the feline spinal cord. J Neurosurg 5 (1981) 200-208
30. Merry WH, Cogbill TH, Annis BL, Lambert PJ: Functional outcome after incomplete spinal cord injuries due to blunt injury. Injury 27 (1996) 17-20
31. Nesathurai S: Steroids and spinal cord injury: revisiting the NASCIS 2 and NASCIS 3 trials. J Trauma 45 (1998) 1088-1093
32. Prendergast MR, Saxe JM, Ledgerwood AM, Lucas CE, Lucas WF: Massive steroids do not reduce the zone of injury after penetrating spinal cord injury. J Trauma 37 (1994) 576-579
33. Rosner MJ: Treatment of spinal cord injury. Letter. J Neurosurg 80 (1994) 954-955
34. Ross IB, Tator CH: Spinal cord blood flow and evoked potential responses after treatment with nimodipine or methylprednisolone in spinal cord-injured rats. Neurosurgery 33 (1993) 470-476
35. Schwab ME, Brosamle C: Regeneration of lesioned corticospinal tract fibers in the adult rat spinal cord under experimental conditions. Spinal Cord 35 (1997) 469-473
36. Shepard MJ, Bracken MB: The effect of methylprednisolone, naloxone, and spinal cord trauma on four liver enzymes: observations from NASCIS 2. Paraplegia 32 (1994) 236-245
37. Statistisches Bundesamt der Bundesrepublik Deutschland, Wiesbaden: Gesundheitsbericht für Deutschland; Krankheitshäufigkeitsarten. Metzler Poeschel Stuttgart 1998
38. Tator C, Fehlings M: Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 75 (1991) 15-26
39. Vale FL, Burns J, Jackson AB, Hadley MN: Combined medical and surgical treatment after acute spinal cord injury: results of a prospective pilot study to assess the merits of aggressive medical resuscitation and blood pressure management. J Neurosurg 87 (1997) 239-246
40. Walker MD: Clinical alert. National Institute on Neurological Disorders and Stroke. Public Health Services: National Institute of Health. US Department of Health & Human Services: Bethesda, Maryland, 1990
41. Weber F, Bock WJ: Notfalltherapie spinaler Traumen. Intensivmed 34 (1997) 725-732
42. Weiss R: Drug reduces paralysis after spinal injury. Science News 137 (1990) 212
43. Young W: Methylprednisolone treatment of acute spinal cord injury: An introduction. J Neurotrauma 8[Suppl 1] (1991) S43-S46
44. Yusuf S, Collins R, Peto R: Why do we need some large, simple randomised trials? Stat Med 3 (1984) 409-420.