Identification of Tyr413 as an Active Site Residue in the Flavoprotein Tryptophan 2-Monooxygenase and Analysis of Its Contribution to Catalysis

Biochemistry

Volumn 42, Issue 47, 2003, Pages 13833-13838

  Sobrado, Pablo ^a,b   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; CARBOXYLATION; CATALYST ACTIVITY; CHARGE TRANSFER; HYDROGEN BONDS; MUTAGENESIS; OXIDATION; RATE CONSTANTS; SUBSTITUTION REACTIONS;

WAVELENGTH CHARGES;

ENZYMES;

ACETAMIDE DERIVATIVE; ALANINE; AMINE OXIDASE (FLAVIN CONTAINING); AMINO ACID; AMINOBENZOIC ACID; CARBON DIOXIDE; FLAVOPROTEIN; HYDROGEN; HYDROGEN PEROXIDE; META TYROSINE; MUTANT PROTEIN; PHENYLALANINE; PYRUVIC ACID; TRYPTOPHAN; UNSPECIFIC MONOOXYGENASE; WATER;

ANIMAL CELL; ARTICLE; BINDING COMPETITION; CATALYSIS; COMPLEX FORMATION; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME KINETICS; MUTATION; NONHUMAN; OXIDATION; PH; PKA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTON TRANSPORT; SEQUENCE HOMOLOGY; WILD TYPE;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONSERVED SEQUENCE; FLAVOPROTEINS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PSEUDOMONAS; SPECTROPHOTOMETRY; TYROSINE; VIPER VENOMS;

ANIMALIA;

EID: 0345014789     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035300i     Document Type: Article

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