Synthesis of fused heterocycles from β-enaminonitrile and carbonyl compounds

Synlett

Volumn , Issue 2, 1999, Pages 222-224

  Nemes, Péter ^b   Balázs, Barbara ^a   Tóth, Gábor ^a   Scheiber, Pál ^b  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b UNIVERSITY OF VETERINARY MEDICINE   (Hungary)

Author keywords

Benzoquinolizines; Cyclisation; Dehydration; Enones; enaminonitrile

Indexed keywords

ALDEHYDE; ALKENE DERIVATIVE; CARBONYL DERIVATIVE; HETEROCYCLIC COMPOUND; KETONE; NITRILE; QUINOLIZINE DERIVATIVE;

ARTICLE; CYCLIZATION; DEHYDRATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

EID: 0345003850     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2574     Document Type: Article

References (23)

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16. 4) and evaporation of the solvent the residue was crystallised from ethanol.
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19. Preparation of compounds 3c-d, 5, 7 and 8: 0.01 mol of 1 was dissolved in 30 ml of ethanol, containing (0.01 mol) of EtONa. 0.01 mol of the enone was added, and the solution heated at reflux. After cooling the crystalline product was filtered, or the ethanol solution evaporated, water was added and extracted with dichloromethane. After drying and evaporation of the solvent the residue was crystallised from ethanol.
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23. ax-7), 6.63 (1H, s, H-8), 3.89 (3H, s, 9-MeO), 3.94 (3H, s, 10-MeO) 7.70 (1H, s, H-11).