Involvement of nitric oxide in the inhibition of aortic smooth muscle cell proliferation by calcium dobesilate

International Journal of Angiology

Volumn 8, Issue SUPPL. 1, 1999, Pages

  Parés Herbuté, Núria ^a   Fliche, Elisabeth ^a   Monnier, Louis ^a  

^a UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DOBESILATE CALCIUM; NITRIC OXIDE;

ANIMAL EXPERIMENT; AORTA MEDIA; ARTERY INTIMA PROLIFERATION; ATHEROGENESIS; CELL PROLIFERATION; CONFERENCE PAPER; DNA SYNTHESIS; DOSE TIME EFFECT RELATION; DRUG EFFECT; GROWTH INHIBITION; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

EID: 0345003835     PISSN: 10611711     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf01619842     Document Type: Conference Paper

References (23)

1. Ross R (1993) The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature (Lond) 362:801-809.
2. Moncada S, Higgs A (1993) The L-arginine-nitric oxide pathway. N Engl J Med 329:2002-2012.
3. Sarkar R, Webb RC (1998) Does nitric oxide regulate smooth muscle cell proliferation? J Vasc Res 35:135-142.
4. Penn M, Chisolm G (1994) Oxidized lipoproteins, altered cell function and atherosclerosis. Atherosclerosis 108:S21-S29.
5. Björkerud S, Björkerud B (1994) Lipoproteins are major and primary mitogens and growth promoters for human arterial smooth muscle cells and lung fibroblasts in vitro. Arterioscler Thromb 14:288-289.
6. Björkerud B, Björkerud S (1996) Contrary effects of lightly and strongly oxidized LDI. with potent promotion of growth versus apoptosis on arterial smooth muscle cells, macrophages, and fibroblasts. Arterioscler Thromb Vasc Biol 16:416-424.
7. Heidrich H, Gerke E, Nekarda H (1983) Inhibition of platelet aggregation under calcium dobesilate. Arzneimittelforsch/Drug Res 33:580-582.
8. Michal M, Giessinger N (1985) Effect of calcium dobesilate and its interaction with aspirin on thrombus formation in vivo. Thromb Res 40:215-226.
9. Suschek C, Kolb H, Kolb-Bachofen V (1997) Dobesilate enhances endothelial nitric oxide synthase activity in macro- and microvascular endothelial cells. Br J Pharmacol 122:1502-1508.
10. Ruiz E, Lorente R, Tejerina T (1997) Effects of calcium dobesilate on the synthesis of endothelium-dependent relaxing factors in rabbit isolated aorta. Br J Pharmacol 121:711-716.
11. Brunet J, Farine JC, Garay RP, Hannaert P (1998) In vitro antioxidant properties of calcium dobesilate. Fundam Clin Pharmacol 12:205-212.
12. Graber R, Parine J-C, Losa GA (1998) Calcium dobesilate protects human peripheral blood mononuclear cells from oxidation and apoptosis. Apoptosis 3:41-49.
13. Parés-Herbuté N, Hillaire-Buys D, Etienne P, Gross R, Loubatières-Mariani M-M, Monnier L (1996) Adenosine inhibitory effect of enhanced growth of aortic smooth muscle cells from streptozotocine-induced diabetic rats. Br J Pharmacol 311:783-789.
14. Schini VB, Catovsky S, Schray-Utz B, Busse R, Vanhoutte PM (1994) Insulin-like growth factor I inhibits induction of nitric oxide synthase in vascular smooth muscle cells. Circ Res 74:24-32.
15. Schumaker VN, Puppione D (1986) Sequential flotation ultracentrifugation. Methods Enzymol 128:155-170.
16. Esterbauer H, Striegl G, Puhl H, Rotheneder M (1989) Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic Res Comm 6:67-75.
17. Sinzinger H, Rauscha R, Vinazzer H (1987) Platelet function and prostaglandins in patients with peripheral vascular disease treated with calcium dobesilate. Prostaglandins Leukot Mcd 29:1-9.
18. Benakis A, Glasson B, Bouvier CA, et al. (1974) Métabolisme et pharmacocinétique du dobésilate de calcium chez l'homme. Thérapie 29:211-219.
19. 2 production by vascular smooth muscle cells. Biochem Biophys Res Commun 194:420-424.
20. Garg UC, Hassid A (1989) Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83:1774-1777.
21. Chen L, Haught WH, Yang B, Saldcen TGP, Parathasarathy S, Mehta JL (1997) Preservation of endogenous antioxidant activity and inhibition of lipid pcroxidation as common mechanisms of antiatherosclerotic effects of vitamin E, lovastalin and amlodipine. J Am Coll Cardiol 30:569-575.
22. Guyton JR, Lenz ML, Mathews B, et al. (1995) Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. Atherosclerosis 118:237-249.
23. Corsini A, Mazzotti M, Raiteri M, et al. (1993) Relationship between mevalonate pathway and arterial myocyte proliferation: In vitro studies with inhibitors of HMG-CoA reductase. Atherosclerosis 101:117-125.