Topical treatment of tungiasis: A randomized, controlled trial

Annals of Tropical Medicine and Parasitology

Volumn 97, Issue 7, 2003, Pages 743-749

  Heukelbach, J ^a   Eisele, M ^b   Jackson, A ^b   Feldmeier, H ^b  

^a Fundacao Mandacaru   (Brazil)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FOLDAN; IVERMECTIN; METRIFONATE; PLACEBO; TIABENDAZOLE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; FLEA; FOOT; HUMAN; INFANT; INFESTATION; LOTION; MAJOR CLINICAL STUDY; MALE; NEWBORN; OINTMENT; RANDOMIZED CONTROLLED TRIAL; TOPICAL TREATMENT; TREATMENT OUTCOME; TUNGIASIS;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; ANIMALS; ANTIPARASITIC AGENTS; BRAZIL; CHILD; CHILD, PRESCHOOL; ECTOPARASITIC INFESTATIONS; FEMALE; FLEAS; HUMANS; INFANT; IVERMECTIN; MALE; MIDDLE AGED; OINTMENTS; THIABENDAZOLE; TREATMENT OUTCOME; TRICHLORFON;

ARACHNIDA; HEXAPODA; SIPHONAPTERA (FLEAS); TUNGA; TUNGA PENETRANS;

EID: 0344984297     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1179/000349803225002408     Document Type: Article

References (28)

1. Ade-Serrano, M. A., Olomolehin, O. G. & Adewunmi, A. (1982). Treatment of human tungiasis with niridazole (Ambilhar): a double-blind placebo-controlled trial. Annals of Tropical Medicine and Parasitology, 76, 89-92.
2. Cardoso, A. (1981). Generalized tungiasis treated with thiabendazole. Archives of Dermatology, 117, 127.
3. Cardoso, A. E. C. (1990). Tunguiase. Anais Brasileiros de Dermatologia, 65, 29S-33S.
4. Carvalho, R. W., Almeida, A. B., Barbosa-Silva, S. C., Amorim, M., Ribeiro, P. C. & Serra-Freire, N. M. (2003). The patterns of tungiasis in Araruama township, state of Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, 98, 31-36.
5. Caumes, E. (2003). Treatment of cutaneous larva migrans and Toxocara infection. Fundamental and Clinical Pharmacology, 17, 213-216.
6. Chadee, D. D. (1994). Distribution patterns of Tunga penetrans within a community in Trinidad, West Indies. Journal of Tropical Medicine and Hygiene, 97, 167-170.
7. Chadee, D. D. (1998). Tungiasis among five communities in south-western Trinidad, West Indies. Annals of Tropical Medicine and Parasitology, 92, 107-113.
8. Eisele, M., Heukelbach, J., van Marck, E., Mehlhorn, H., Meckes, O., Franck, S. & Feldmeier, H. (2003). Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: I. Natural history of tungiasis in man. Parasitology Research, 90, 87-99.
9. Feldmeier, H. & Chitsulo, L. (1999). Therapeutic and operational profiles of metrifonate and praziquantel in Schistosoma haematobium infection. Arzneimittel-Forschung Drug Research, 49, 557-565.
10. Feldmeier, H. & Doehring, E. (1987). Clinical experience with metrifonate. Review with emphasis on its use in endemic areas. Acta Tropica, 44, 357-368.
11. Feldmeier, H., Heukelbach, J., Eisele, M., Sousa, A. Q., Barbosa, L. M. & Carvalho, C. B. (2002). Bacterial superinfection in human tungiasis. Tropical Medicine and International Health, 7, 559-564.
12. Feldmeier, H., Eisele, M., Sabóia Moura, R. C. & Heukelbach, J. (2003). Severe tungiasis in under-privileged communities: case series from Brazil. Emerging Infectious Diseases, 9, 949-955.
13. Heukelbach, J., de Oliveira, F. A., Hesse, G. & Feldmeier, H. (2001). Tungiasis: a neglected health problem of poor communities. Tropical Medicine and International Health, 6, 267-272.
14. Heukelbach, J., Mencke, N. & Feldmeier, H. (2002a). Cutaneous larva migrans and tungiasis: the challenge to control zoonotic ectoparasitoses associated with poverty. Tropical Medicine and International Health, 7, 907-910.
15. Heukelbach, J., Wilcke, T. & Feldmeier, H. (2002b). Epidemiological characteristics of tungiasis. Acta Tropica, 83, S101.
16. Heukelbach, J., Costa, A. L. M., Wilcke, T., Mencke, N. & Feldmeier, H. (2003a). The animal reservoir of Tunga penetrans in poor communities in northeast Brazil. Medical and Veterinary Entomology, in press.
17. Heukelbach, J., van Haeff, E., Rump, B., Wilcke, T., Moura, R. C. & Feldmeier, H. (2003b). Parasitic skin diseases: health care-seeking in a slum in north-east Brazil. Tropical Medicine and International Health, 8, 368-373.
18. Matias, R. S. (1989). Epidemia de tungíase no Rio Grande do Sul. Revista da Sociedade Brasileira de Medicina Tropical, 22, 137-142.
19. Muehlen, M., Heukelbach, J., Wilcke, T., Winter, B., Mehlhorn, H. & Feldmeier, H. (2003). Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil II. Prevalence, parasite load and topographic distribution of lesions in the population of a traditional fishing village. Parasitology Research, in press.
20. Nte, A. R. & Eke, F. U. (1995). Jigger infestation in children in a rural area of Rivers state of Nigeria. West African Journal of Medicine, 14, 56-58.
21. Rietschel, W. (1989). Beobachtungen zum sandfloh (Tunga penetrans) bei mensch und hund in Französisch-Guayana. Tierärztliche Praxis, 17, 189-193.
22. Saraceno, E. F., Bazarra, M. L. G., Calviello, R. C., Quaranta, M. A., Mirarchi, P. & Sánchez, G. F. (1999). Tungiasis: tratamiento de un caso con ivermectina. Archivos Argentinos de Dermatologia, 49, 91-95.
23. Valença, Z. O., Cardoso, A. E. C. & Cardoso, A. S. (1972). Tunguiase generalizada: relato de dois casos tratados com thiabendazol. Dermatologia Ibero-Latino-Americana, 3, 375-378.
24. Victoria, J. & Trujillo, R. (2001). Topical ivermectin: a new successful treatment for scabies. Pediatric Dermatology, 18, 63-65.
25. Victoria, J., Trujillo, R. & Barreto, M. (1999). Myiasis: a successful treatment with topical ivermectin. International Journal of Dermatology, 38, 142-144.
26. Wilcke, T., Heukelbach, J., Cesar Saboia, M. R., Regina, S. K.-P. & Feldmeier, H. (2002). High prevalence of tungiasis in a poor neighbourhood in Fortaleza, northeast Brazil. Acta Tropica, 83, 255-258.
27. Yeruham, I. & Hadani, A. (1998). Control of human scabies by topical application of ivermectin. Annals of Tropical Medicine and Parasitology, 92, 627-629.
28. Youssef, Y. M., Sadaka, H. A. H., Eissa, M. M. & El-Ariny, A. F. (1995). Topical application of ivermectin for human ectoparasites. American Journal of Tropical Medicine and Hygiene, 53, 652-653.