Consistency of Genetic Analyses in Longitudinal Data: Observations from the GAW13 Framingham Heart Study Data

Genetic Epidemiology

Volumn 25, Issue SUPPL. 1, 2003, Pages

  Diego, Vincent P ^a,b   Atwood, Larry ^c   Mathias, Rasika A ^d   Almasy, Laura ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

Genotype x age interaction; Heritability; Linkage; Relative risk

Indexed keywords

AGE; CONFERENCE PAPER; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC TRAIT; GENOME; GENOTYPE; HERITABILITY; HUMAN; LONGITUDINAL STUDY; MEDICAL RESEARCH; QUANTITATIVE GENETICS; QUANTITATIVE TRAIT LOCUS; RISK ASSESSMENT;

AGE FACTORS; CARDIOVASCULAR DISEASES; COMPUTER SIMULATION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE (GENETICS); LONGITUDINAL STUDIES; MODELS, GENETIC; MODELS, STATISTICAL; QUANTITATIVE TRAIT LOCI; REPRODUCIBILITY OF RESULTS; RISK FACTORS;

EID: 0344981450     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.10281     Document Type: Conference Paper

References (20)

1. Atwood LD, Heard-Costa NL, Cupples LA, Levy D. 2003. Consistency of linkage results across exams and methods in the Framingham Heart Study. BMC Genet [Suppl] 4:30.
2. Beck SR, Brown WM, Williams AH, Pierce J, Rich SS, Langefeld CD. 2003. Age-stratified QTL genome scan analysis for anthropometric measures. BMC Genet [Suppl] 4:31.
3. Bergeman CS, Neiderhiser JM, Pedersen NL, Plomin R. 2001. Genetic and environmental influences on social support in later life: a longitudinal analysis. Int J Aging Hum Dev 53:107-135.
4. Brown WM, Beck SR, Lange EM, Davis CC, Kay CM, Langefeld CD, Rich SS. 2003. Age-stratified heritability estimation in the Framingham Heart Study families. BMC Genet [Suppl] 4:32.
5. Carmelli D, Swan GE, Kelly-Hayes M, Wolf PA, Reed T, Miller B. 2000. Longitudinal changes in the contribution of genetic and environmental influences to symptoms of depression in older male twins. Psychol Aging 15:505-510.
6. Chen WJ, Liu P-H, Ho Y-Y, Chien K-L, Lo M-T, Shih W-L, Yen Y-C, Lee W-C. 2003. Sibling recurrence risk ratio analysis of metabolic syndrome and its components over time. BMC Genet [Suppl] 4:33.
7. Cheverud JM, Routman EJ, Duarte FAM, van Swinderen B, Cothran K, Perel C. 1996. Quantitative trait loci for murine growth. Genetics 142:1305-1319.
8. Curtsinger JW, Khazaeli AA. 2002. Lifespan, QTLs, age-specificity, and pleiotropy in Drosophila. Mech Ageing Dev 123:81-93.
9. Diego VP, Almasy L, Dyer TD, Soler JMP, Blangero J. 2003. Strategy and model building in the fourth dimension: a null model for genotype x age interaction as a Gaussian stationary stochastic process. BMC Genet [Suppl] 4:34.
10. Iliadou A, Lichtenstein P, Morgenstern R, Forsberg L, Svensson R, de Faire U, Martin NG, Pedersen NL. 2002. Repeated blood pressure measurements in a sample of Swedish twins: heritabilities and associations with polymorphisms in the rennin-angiotensin-aldosterone system. J Hypertens 20: 1543-1550.
11. Kalousdian S, Fabsitz R, Havlik R, Christian J, Rosenman R. 1987. Heritability of clinical chemistries in an older twin cohort: the NHLBI twin study. Genet Epidemiol 4:1-11.
12. Li X, Wang D, Yang K, Guo X, Lin Y-C, Samayoa CG, Yang H. 2003. Genome-wide linkage analysis using cross-sectional and longitudinal traits for body mass index in a subsample of the Framingham Heart Study. BMC Genet [Suppl] 4:35.
13. Mathias RA, Roy-Gagnon M-H, Justice CM, Papanicolaou GJ, Fan YT, Pugh EW, Wilson AF. 2003. Comparison of year-of-exam and age matched estimates of heritability in the Framingham Heart Study data. BMC Genet [Suppl] 4:36.
14. Patel SR, Celedon JC, Weiss ST, Palmer LJ. 2003. Lack of reproducibility of linkage results in serially measured blood pressure data. BMC Genet [Suppl] 4:37.
15. Pletcher SD, Geyer CJ. 1999. The genetic analysis of age-dependent traits: modeling the character process. Genetics 151:825-835.
16. Plomin R, Pedersen NL, Lichtenstein P, McClearn GE. 1994. Variability and stability in cognitive abilities are largely genetic later in life. Behav Genet 24:207-215.
17. Rice T, Perusse L, Bouchard C, Rao DC. 1999. Familial aggregation of body mass index and subcutaneous fat measures in the longitudinal Quebec Family Study. Genet Epidemiol 16:316-334.
18. Rice T, Rao R, Perusse L, Bouchard C, Rao DC. 2000. Tracking of familial resemblance for resting blood pressure over time in the Quebec Family Study. Hum Biol 72:415-431.
19. Sengul H, Barmada MM. 2003. Stability of exploratory multivariate data modeling in longitudinal data. BMC Genet [Suppl] 4:38.
20. Wadsworth SJ, Corley RP, Hewitt JK, Defries JC. 2001. Stability of genetic and environmental influences on reading performance at 7, 12, and 16 years of age in the Colorado Adoption Project. Behav Genet 31:353-359.