Evaluation of hematopoietic progenitors in hematopoietic progenitor cell transplants. CD34+ dose effect in marrow recovery. Retrospective analysis in 38 patients

Hematology and Cell Therapy

Volumn 41, Issue 4, 1999, Pages 171-177

  Gabus R ^a   Magarinos A ^a   Zamora, M ^a   De Lisa, E ^a   Landoni, A I ^a   Martinez G ^b   Canessa, C ^b   Giordano, H ^b   Bodega, E ^a  

^a HOSPITAL MACIEL   (Uruguay)

^b Hospital Maciel ^*

Author keywords

Comparative analysis; Problem based learning; Teaching of haematology

Indexed keywords

CD34 ANTIGEN;

ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; APHERESIS; ARTICLE; BLOOD TRANSFUSION; BONE MARROW CELL; CLINICAL ARTICLE; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC SYSTEM; HOSPITALIZATION; HUMAN; MALE; NEUTROPHIL; SCHOOL CHILD; THROMBOCYTE COUNT;

ADOLESCENT; ADULT; ANTIGENS, CD34; BLOOD COMPONENT REMOVAL; BONE MARROW TRANSPLANTATION; FEMALE; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHILS; PLATELET COUNT; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 0344980112     PISSN: 12693286     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00282-999-0171-y     Document Type: Article

References (26)

1. Bender JG, To LB, Williams S, Schwartzberg LS (1992) Definding a therapeutic dose of peripheral blood stem cells, J. Hematother 1: 329-41
2. Bensinger W, Appelbaum F, Rowley S et al. (1995) Factors that influence collection of andengrafment of autologous peripheral blood stem cells. J Clin Oncol 13: 2547-55
3. Bridell RA, Hartley CA, Smidt KA, Mc Niece IK (1993) Recombinant rat stem cell factor synergizes with recombinant human granulocyte colony-stimulating factor in vivo in mice to mobilize peripheral blood and progenitor cells that have enhanced repopulating potential. Blood 82: 1720-3
4. Bolwell BJ, Fishleder SW, Andresen AE et al. (1993) G-CSF primed peripheral blood progenitor cells in autologous bone marrow transplantation: Parameters affecting bone marrow engrafment. Bone Marrow Transplant 12: 609-14
5. Dercksen MW, Rodephius S, Dirkson MKA et al. (1995) Subsets od CD34+ cells and rapid hematopoletic recovery afterperipheral-bloo stem-cell tranplantation. J Clin Oncol 13: 1922-32
6. DeRevl T, Appelbaum F, Storb R et al. (1994) Effects of granulocyte colony-stimulating factor and stem cells factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs. Blood 83: 3795-9
7. Mauch P, Lamont C, Neben T-Y et al. (1995) Hematopoietic stem cells in the blood after stem cell factor and interleukin-11 administratrion: evidence for differernt mechanisms of mobilization. Blood 86: 4674-80
8. Mavroudis D, Read E, Cottler-Fox et al. (1996) CD34+ cell dose predicts survival, positransplant morbidity, and rate of hamatologie recovery after allogenic marrow transplants for hematologie malignancies. Blood 88: 3223-9
9. Moore MA (1991) Clinical implications of positive and negative hematopoietic stem cell regulators. Blood 78: 1-19
10. Glaspy JA, Shpall EJ, LeMaistre CF, Bridell RA, Menchaca DM, Turner SA, Lill M, Chap L, Jones R, Wiers MD, Sheridan WP, McNiece IK (1997) Peripheral blood progenitor cell mobilization using Stem Cell Factor with Filgrastim in Breast cancer Patients. Bloods 90: 2939-51
11. Glaspy JA, Lu ZJ, Schpall EJ et al. (1997) Economic ratinales for infusing optimal number of CD34+ cells in peripheral blood progenitor cell transplants. ASH: 465-III
12. Faucher C, Le Corroller LE, Chabannon C, Biaise D et al. (1996) Autologous transplantation of blood stem cells mobilized with Filigrastim alone in 93 patients with Malignanciers: The number of CD34+ cells reinfused is the only factor prediciting both granulocyte and platelet recovery. J Hematotherapy 5: 663-670
13. Hartman O, Le Corroller AG, Biaise D et al. (1997) Peripherical blood stem cell and Bone Marrow Transplantation for solid tumors and lymphomas: Hematologic recovery and Costs. Ann Intern Med 126: 600-607
14. Ho AD, Young D, Maruyama M et al. (1996) Pluripotent and lineage-commited CD34+ aubects in leukapheresis products mobilized by G-CSF, GM-CSF vs. A combination of both. Exp Hematol 24: 1460-8
15. Ketterer N, Salles G, Raba M, Coiffler B et al. (1998) High CD34+ Cell counts decrease hematologie toxicity of autologous peripheral blood progenitor cell transplantation. Blood 91: 3148-55
16. Peault B, Weissman IL, Buckle AM et al. (1993) Thy-1 expression CD34+ human cells express multiple hematopoietic potentialities in vitro and in SCID-hu mice. Nouv Rec Fr Hematol 35: 91-3
17. Terstappen LWMM, Hunng S, Safford M et al. (1991) Sequential generations of hematopoietic colonies derivided from single monlincage-commited CD34+CD38- progenitor cells. Blood 77: 1218-27
18. Rusten L, Jacobsen SEW, Kaalhus O et al. (1994) Functional differences between CD38- and DR-subfractions of CD34+ bone marrow cells. Blood 84: 1473-81
19. Sheridan WP, Bergley CG, Juttner CA (1992) Effect of peripheral blood progenitor cells mobilized by filgrastim (G.CSF) on platelet recovery after high dose chemotherapy. Lancet 339: 640-4
20. Sheridan WP, Bergley CG, To LB (1994) Phase II study of autologous filgrastim (G.CSF) mobilized peripheral bloos progenitor cells to retore hematopolesis after high dose chemotherapy for lymphoid malignancies. Bone Marow Transplant 14: 105-11
21. Shpall EJ, Wheeler SA, Turner S, Glaspy et al. (1997) A randomized phase 3 study of PBSC mobilization by stem cell factor and filgrastim in patients with high-risk breast cancer. ASH: 2627
22. Srour EF, Zanjani DE, Cornetta K et al. (1993) Persistence of human multilincage, selfrenewing lymphohematopoietic stem cells in chimeric sheep. Blood 82: 3333-42
23. Stadmauer EA, Schneider CJ, Silberastein LE (1995) Peripheral blood progenitor cell generation and harvesting, Semin Oncol 22: 291-300
24. Suterland DR, Anderson L, Keeney M at al. (1996) The ISHAGE guidelines for CD34+ cell determination by flow citometry. J Hematother 5: 213-26
25. Watts MJ, Sullivan AM, Jamieson E (1997) Progenitor-cell mobilization after low dose cyclophosphamide and granulocyte colony-stimulating factor: an analysis of progenitor-cell quality and quality and factors predicting for these parameters in 101 pretreated patients with malignant lymphoma. JclinOncol 15: 535-46
26. Weaver CH, Birch R, Schulman KA (1997) Effect of cell dose on ressource utilization in patients undergoing transplant with peripheral blood progenitor cells. ASH: 1647