Psychosine blocks quisqualate-induced glutamate excitotoxicity in hippocampal CA sector neurons

Brain Research

Volumn 802, Issue 1-2, 1998, Pages 1-8

  Hodgson, D M ^a,b   Taylor, A N ^a,b   Zhang, Z ^c   Rosenberg, A ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glutamate excitotoxicity; Hippocampus; Lysosphingolipid; Neuroprotection; Psychosine; Quisqualate

Indexed keywords

CALCIUM ION; GLUTAMIC ACID; METABOTROPIC RECEPTOR; MICROTUBULE ASSOCIATED PROTEIN 2; PHOSPHOLIPASE C; PSYCHOSINE; QUISQUALIC ACID;

AGONIST; AKINESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CONVULSION; DEGENERATIVE DISEASE; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; HIPPOCAMPUS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NERVE INJURY; NEUROTOXICITY; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECEPTOR BLOCKING; RECEPTOR DENSITY; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; CELL COUNT; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PSYCHOSINE; QUISQUALIC ACID; RATS; RATS, INBRED F344;

EID: 0344973028     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00508-3     Document Type: Article

References (26)

1. L. Aniksztejn, P. Bregestovski, Y. Ben-Ari, Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses, Eur. J. Pharmacol. 205 (1991) 327-328.
2. Y. Bessho, H. Nawa, S. Nakanishi, Glutamate and quisqualate regulate expression of metabotropic glutamate receptor mRNA in cultured cerebellar cells, J. Neurochem. 60 (1993) 253-259.
3. S. Cockcroft, M.H. Thomas, Inositol-lipid-specific phospholipase C isozymes and their differential regulation by receptors, Biochem. J. 288 (1992) 1-14.
4. P.J. Conn, J.-P. Pin, Pharmacology and functions of metabotropic glutamate receptors, Annu. Rev. Pharmacol. Toxicol. 37 (1997) 205-237.
5. C.H. Davies, V.R.J. Clarke, D.E. Jane, C.L. Collingridge, Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurons, Br. J. Pharmacol. 116 (1995) 1859-1869.
6. S.M. Fitzjohn, A.J. Irving, M.J. Palmer, J. Harvey, D. Lodge, Activation of Group 1 mGluR' s potentiates NMDA responses in rat hippocampal slices, Neurosci. Lett. 203 (1996) 211-213.
7. M. Hollemann, S. Heinemann, Cloned glutamate receptors, Annu. Rev. Neurosci. 17 (1994) 31-108.
8. R.L. Isaacson, K.H. Pribram, The hippocampus, Vol. IV, Plenum, New York, 1985.
9. G.V. Johnson, J.M. Litersky, R.S. Jope, Degradation of microtubule associated protein and brain spectrin by calpain: a comparative study, J. Neurochem. 56 (1980) 1630-1635.
10. K.W. Kaatz, R.L. Albin, Intraseptal administration of (1S,3R)-1-aminocyclopentane-1,3 dicarboxylic acid induces immediate early gene expression in lateral septal neurons, Brain Res. 709 (1995) 205-214.
11. M. Morales, E. Fifkova, Distribution of MAP-2 in dendritic spines and its co-localization with actin, Cell Tissue Res. 256 (1989) 447-456.
12. S. Nakanishi, Molecular diversity of glutamate receptors and implications for brain function, Science 258 (1992) 597-603.
13. G. Paxinos, C. Watson, The rat brain in stereotaxic coordinates, Academic Press, New York, 1992.
14. J.P. Pin, C. Joly, S.F. Heinemann, J. Bockaert, Domains involved in specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors, EMBO J. 13 (1994) 342-348.
15. L.D. Pozzo-Miller, N.H. Pivovarova, R.D. Leapman, R.A. Buchanan, T.S. Reese, R.B. Andews, Activity dependent calcium sequestration in dendrites of hippocampal neurons in brain slices, J. Neurosci. 17 (1997) 8729-8738.
16. T. Ritchie, A. Rosenberg, E.P. Noble, Regulation of phosphoinositide hydrolysis in cultured astrocytes by sphingosine and psychosine, Biochem. Biophys. Res. Commun. 186 (1992) 790-795.
17. C. Romano, M.A. Sesma, C.T. McDonald, K. O'Malley, A.N. Van den Pol, Distribution of metabotropic glutamate receptor mRNA immunoreactivity in rat brain, J. Comp. Neurol. 355 (1995) 455-469.
18. A.I. Sacaan, D.D. Schoepp, Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage, Neurosci. Lett. 139 (1992) 77-82.
19. D.D. Schoepp, Novel functions for subtypes of metabotropic glutamate receptors, Neurochem. Int. 24 (1994) 439-449.
20. D.D. Schoepp, J. Bockaert, F. Sladeczek, Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors, Trends Pharmacol. Sci. 11 (1990) 508-515.
21. H. Shinoda, T. Kobayashi, M. Katayama, I. Goto, H. Naggia, Accumulation of galactosylsphingosine (psychosine) in the Twitcher mouse: determination by HPLC, J. Neurochem. 49 (1987) 92-99.
22. R. Simon, J.C. Noszek, C. Kegerize, Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage, J. Neurosci. 65 (1989) 1579-1590.
23. F. Sladaczek, J.-P. Pin, M. Recasens, J. Bockaert, S. Weiss, Glutamate stimulates inositol phosphate formation in striatal neurons, Nature 317 (1985) 717-719.
24. q class of G protein, Nature 350 (1991) 516-518.
25. G.W. Taylor, L.R. Merlin, R.K. Wong, Synchronized oscillations in hippocampal CA3 neurons induced by metabotropic glutamate receptor activation, J. Neurochem. 15 (1995) 8039-8052.
26. 2+ in α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-mediated polyphosphoinositide turnover in primary neuronal cultures, J. Neurochem. 62 (1994) 2325-2331.