Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

Journal of Molecular and Cellular Cardiology

Volumn 35, Issue 4, 2003, Pages 357-366

  Borutaite, Vilmante ^a,b   Jekabsone, Aiste ^b   Morkuniene, Ramune ^b   Brown, Guy C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

Author keywords

Apoptosis; Caspases; Cytochrome c; Ischemia; Mitochondrial permeability transition; Respiration

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CASPASE 3; CASPASE 3 INHIBITOR; CYCLOSPORIN A; CYTOCHROME C; PROTEINASE; TACROLIMUS;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; DNA STRAND BREAKAGE; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NICK END LABELING; NONHUMAN; PREVENTION; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT;

EID: 0344951187     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2828(03)00005-1     Document Type: Article

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