Trends in antimicrobial utilization at a Spanish general hospital during a 5-year period

Pharmacoepidemiology and Drug Safety

Volumn 12, Issue 3, 2003, Pages 243-247

  Nájera, Lorena Hermosilla ^a   Blasco, Andrés Canut ^b   Sanz, Miguel Ulibarrena ^b   Osinaga, Eider Abasolo ^a   Inchaurregui, Luis Carlos Abecia ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b HOSPITAL TXAGORRITXU   (Spain)

Author keywords

Antimicrobials; Consumption; Drug utilization studies; Hospital; ICU

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOGLYCOSIDE DERIVATIVE; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIINFECTIVE AGENT; BETA LACTAM ANTIBIOTIC; CARBAPENEM DERIVATIVE; CEFAZOLIN; CEFIXIME; CEFONICID; CEFOTAXIME; CEFTRIAXONE; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; COTRIMOXAZOLE; DOXYCYCLINE; GENTAMICIN; GLYCOPEPTIDE; IMIPENEM; METRONIDAZOLE; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SULFONAMIDE; TOBRAMYCIN; TRIMETHOPRIM; UNINDEXED DRUG; VANCOMYCIN;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG UTILIZATION; GENERAL HOSPITAL; HOSPITAL FINANCE; HOSPITAL PATIENT; HOSPITAL PHARMACY; HOSPITAL PLANNING; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; MEDICAL RECORD; PATIENT CARE; PRIORITY JOURNAL; RESOURCE ALLOCATION; RETROSPECTIVE STUDY; SPAIN; UTILIZATION REVIEW;

ANTI-INFECTIVE AGENTS; DATABASES, FACTUAL; DRUG UTILIZATION; HOSPITALS, GENERAL; HUMANS; INTENSIVE CARE UNITS; RETROSPECTIVE STUDIES; SPAIN;

EID: 0344951002     PISSN: 10538569     EISSN: None     Source Type: Journal    
DOI: 10.1002/pds.768     Document Type: Article

References (19)

1. Domínguez Rojas V, Ortega Molina P, Astasio Arbiza P, de Juanes Pardo JR. Farmacovigilancia. Farmacoepidemiología. In Piédrola Gil Medicina Preventiva y Salud Pública (10th edn), Gil P (ed.). Masson: Barcelona, 2001; 189-198.
2. McElnay JC, Scott MG, Sidara JY, Kearney P. Audit of antimicrobial usage in a medium-sized general hospital over an 11-year period. The impact of antibiotic policies. Pharm World Sci 1995; 17: 7-13.
3. Neu HC. The crisis in antibiotic resistance. Science 1992; 257: 1064-1073.
4. Cohen ML. Epidemiology of drug resistance: implications for a post-antimicrobial era. Science 1992; 257: 1050-1055.
5. Friedrich LV, White RL, Bosso JA. Impact of use of multiple antimicrobials on changes in susceptiblity of gram-negative aerobes. Clin Infect Dis 1999; 28: 1017-1024.
6. White RL, Friedrich LV, Mihm LB, Bosso JA. Assessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient care areas. Clin Infect Dis 2000; 31: 16-23.
7. López Lozano JM, Monnet DL, Yagüe A, et al. Modelling and forecasting antimicrobial resistance and its dynamic relationship to antimicrobial use: a time series analysis. Int J Antimicrob Agents 2000; 14: 21-31.
8. WHO Collaborating Center for Drug Statistics. Anatomial Therapeutic Chemical (ATC) Classification and Defined Daily Doses (DDD). WHO: Oslo, 1997.
9. Cobos García FJ, Caméan Fernández M, Santos Ramos B, et al. Utilización de antimicrobianos en los hospitales públicos de Andalucía: 1995-1996. Farm Hosp (Esp Congr) 1997; 21: 272-282.
10. Spanish Society of Hospital Pharmacy Study Group. DDDs: resultados del año 1998. Rev SEFH 2000; 91: 21-29.
11. Fridkin SK, Steward CD, Edwards JR, et al. Surveillance of antimicrobial use and antimicrobial resistance in United States hospitals: project ICARE Phase 2. Clin Infect Dis 2000; 31: 16-23.
12. Alfaro A, Barajas MT, Rodríguez B, Manso P, Sainz de Rozas C, Martínez MJ. Evolución del consumo de antibióticos en un hospital general (1992-1998). Farm Hosp (Esp Congr) 1999; 23: 98.
13. Verdejo Reche F, Villejas Aranda JMa, Tarín Remohi MaJ, Alférez García I, Ortega Jiménez JMa. Consumo de antimicrobianos en un hospital de especialidades durante los años 1996-1997. Farm Hosp (Esp Congr) 1999; 23: 98.
14. Gantes Trelles J, Mateo Quintero J, Villanueva Jiménez P, Sánchez Piñero J, Dávila Guerrero J. Evolución del consumo de antiinfecciosos durante los años 1995-1997 en un hospital comarcal. Farm Hosp (Esp Congr) 1999; 23: 98.
15. Martínez Sanz H, Castera Melchor E, Catalá Pizarro RMa, Cobos García FJ, Sacristán de Lama MaP, Sora Ortega M. Utilización de antiinfecciosos en los hospitales españoles: 1997-1999. Farm Hosp (Esp Congr) 2001; 25: 3-12.
16. García Martín A. Evolución del consumo de antimicrobianos. Farm Hosp (Esp Congr) 1998; 22: 79.
17. Cía MA, Mateo M, Raga A. Evolución del consumo de antibióticos durante los años 1995-1998. Farm Hosp (Esp Congr) 1999; 23: 98.
18. Sora M, Juvany R, Jódar R, et al. Análisis de la evolución del consumo de antimicrobianos durante la última década en cuatro hospitales de tercer nivel de Barcelona. Farm Hosp (Esp Congr) 2000; 24: 81.
19. Harbarth S, Viot M, Beeler I, Klastersky J, Szucs T. Variation in antimicrobial utilization for febrile neutropenia in cancer patients. The CEMIC Study Group. Club d'Etudes des Maladies Infectieuses en Cancer. Infection 2000; 28: 375-378.