-
1
-
-
0019891328
-
Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion
-
Okamoto S, Hijikata A: Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion. Biochem Biophys Res Commun 1981; 101:440-446.
-
(1981)
Biochem Biophys Res Commun
, vol.101
, pp. 440-446
-
-
Okamoto, S.1
Hijikata, A.2
-
3
-
-
15144361588
-
Novastan (brand of argatroban): A small-molecule, direct thrombin inhibitor
-
Hursting MJ, Alford KL, Becker JC, Brooks RL, Joffrion JL, Knappenberger GD, Kogan PW, Kogan TP, McKinney AA, Schwarz RP: Novastan (brand of argatroban): A small-molecule, direct thrombin inhibitor. Semin Thromb Hemost 1997;23:503-516.
-
(1997)
Semin Thromb Hemost
, vol.23
, pp. 503-516
-
-
Hursting, M.J.1
Alford, K.L.2
Becker, J.C.3
Brooks, R.L.4
Joffrion, J.L.5
Knappenberger, G.D.6
Kogan, P.W.7
Kogan, T.P.8
McKinney, A.A.9
Schwarz, R.P.10
-
5
-
-
0026347092
-
Argatroban, a selective, potent thrombin inhibitor
-
Bush LR: Argatroban, a selective, potent thrombin inhibitor. Cardiovasc Drug Rev 1991;9:247-263.
-
(1991)
Cardiovasc Drug Rev
, vol.9
, pp. 247-263
-
-
Bush, L.R.1
-
6
-
-
0026563721
-
A strategy for a rational approach to designing synthetic selective inhibitors
-
Hijikata-Okunomiya A, Okamoto S: A strategy for a rational approach to designing synthetic selective inhibitors. Semin Thromb Hemost 1992;18:135-149.
-
(1992)
Semin Thromb Hemost
, vol.18
, pp. 135-149
-
-
Hijikata-Okunomiya, A.1
Okamoto, S.2
-
7
-
-
0021327417
-
2-[(3-methyl-1,2,3,4-tetrahy dro-8-quinolinyl)sulfonyl]-L-arginyl)]- 2-piperi-dinecarboxylic acid
-
2-[(3-methyl-1,2,3,4-tetrahy dro-8-quinolinyl)sulfonyl]-L-arginyl)]- 2-piperi-dinecarboxylic acid. Biochemistry 1984;23:85-90.
-
(1984)
Biochemistry
, vol.23
, pp. 85-90
-
-
Kikumoto, R.1
Tamao, Y.2
Tezuka, T.3
Tonomura, S.4
Hara, H.5
Ninomiya, K.6
Hijikata, A.7
Okomoto, S.8
-
8
-
-
0027742161
-
Inhibitor binding to thrombin with x-ray crystallographic studies
-
Banner DW, Hadvary P: Inhibitor binding to thrombin with x-ray crystallographic studies. Adv Exp Med Biol 1993;340:27-33.
-
(1993)
Adv Exp Med Biol
, vol.340
, pp. 27-33
-
-
Banner, D.W.1
Hadvary, P.2
-
9
-
-
0027741220
-
Crystallographic determination of thrombin complexes with small synthetic inhibitors as a starting point for the receptor-based design of antithrombotics
-
Bauer M, Brandstetter H, Turk D, Sturzebekker J, Bode W: Crystallographic determination of thrombin complexes with small synthetic inhibitors as a starting point for the receptor-based design of antithrombotics. Semin Thromb Hemost 1993;19:352-360.
-
(1993)
Semin Thromb Hemost
, vol.19
, pp. 352-360
-
-
Bauer, M.1
Brandstetter, H.2
Turk, D.3
Sturzebekker, J.4
Bode, W.5
-
10
-
-
0022980224
-
Pharmacokinetic studies of argatroban (MD-805): Protein binding and blood cell binding
-
Tatsuno J, Komatsu T, Iida S: Pharmacokinetic studies of argatroban (MD-805): Protein binding and blood cell binding. Jap Pharmacol Ther 1986;14(suppl 5):243-249.
-
(1986)
Jap Pharmacol Ther
, vol.14
, Issue.5 SUPPL.
, pp. 243-249
-
-
Tatsuno, J.1
Komatsu, T.2
Iida, S.3
-
11
-
-
0028004409
-
Antithrombotic actions of argatroban in rat models of venous, mixed and arterial thrombosis, and its effects on the tail transection bleeding time
-
Berry CN, Girard D, Lochot S, Lecoffre C: Antithrombotic actions of argatroban in rat models of venous, mixed and arterial thrombosis, and its effects on the tail transection bleeding time. Br J Pharmacol 1994;113:1209-1214.
-
(1994)
Br J Pharmacol
, vol.113
, pp. 1209-1214
-
-
Berry, C.N.1
Girard, D.2
Lochot, S.3
Lecoffre, C.4
-
12
-
-
0027959329
-
Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: Comparison with heparin and recombinant hirudin
-
Berry CN, Girardot C, Lecoffre C, Lunven C: Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: Comparison with heparin and recombinant hirudin. Thromb Haemost 1994;72:381-386.
-
(1994)
Thromb Haemost
, vol.72
, pp. 381-386
-
-
Berry, C.N.1
Girardot, C.2
Lecoffre, C.3
Lunven, C.4
-
13
-
-
0032530735
-
No effect of clot age or thrombolysis on argatroban's inhibition of thrombin
-
Hantgan RR, Jerome WG, Hursting MJ: No effect of clot age or thrombolysis on argatroban's inhibition of thrombin. Blood 1998;92: 2064-2074.
-
(1998)
Blood
, vol.92
, pp. 2064-2074
-
-
Hantgan, R.R.1
Jerome, W.G.2
Hursting, M.J.3
-
14
-
-
0034049121
-
The pharmacokinetics and pharmacodynamics of argatroban: Effects of age, gender, and hepatic or renal dysfunction
-
Swan SK, Hursting MJ: The pharmacokinetics and pharmacodynamics of argatroban: Effects of age, gender, and hepatic or renal dysfunction. Pharmacotherapy 2000;20:318-329.
-
(2000)
Pharmacotherapy
, vol.20
, pp. 318-329
-
-
Swan, S.K.1
Hursting, M.J.2
-
15
-
-
0033937140
-
Comparison of anticoagulant effects and safety of argatroban and heparin in healthy subjects
-
Swan SK, St. Peter JV, Lambrecht LJ, Hursting MJ: Comparison of anticoagulant effects and safety of argatroban and heparin in healthy subjects. Pharmacotherapy 2000;20:756-770.
-
(2000)
Pharmacotherapy
, vol.20
, pp. 756-770
-
-
Swan, S.K.1
St. Peter, J.V.2
Lambrecht, L.J.3
Hursting, M.J.4
-
16
-
-
0003276855
-
Effect of renal function on the pharmacokinetics and pharmacodynamics of argatroban (a direct thrombin inhibitor)
-
Hursting MJ, Joffrion JL, Brooks RL, Swan SK: Effect of renal function on the pharmacoki-netics and pharmacodynamics of argatroban (a direct thrombin inhibitor). Blood 1996; 88(suppl 1):167a.
-
(1996)
Blood
, vol.88
, Issue.1 SUPPL.
-
-
Hursting, M.J.1
Joffrion, J.L.2
Brooks, R.L.3
Swan, S.K.4
-
17
-
-
0001151469
-
Effect of hepatic function on the pharmacokinetics and pharmacodynamics of argatroban
-
Hursting MJ, Becker JC, Joffrion JL, Knappenberger GD, Schwarz RP: Effect of hepatic function on the pharmacokinetics and pharmacodynamics of argatroban. Thromb Haemost 1997(suppl);493-494.
-
(1997)
Thromb Haemost
, Issue.SUPPL.
, pp. 493-494
-
-
Hursting, M.J.1
Becker, J.C.2
Joffrion, J.L.3
Knappenberger, G.D.4
Schwarz, R.P.5
-
18
-
-
0023035819
-
Pharmacokinetics studies of argatroban (MD-805) in human - Concentrations of argatroban and its metabolites in plasma, urine and feces during and after drip intravenous infusion
-
in Japanese
-
Izawa O, Katsuki M, Komatsu T, Iida S: Pharmacokinetics studies of argatroban (MD-805) in human - Concentrations of argatroban and its metabolites in plasma, urine and feces during and after drip intravenous infusion (in Japanese). Jpn Pharmacol Ther 1986;14(suppl 5):251-263.
-
(1986)
Jpn Pharmacol Ther
, vol.14
, Issue.5 SUPPL.
, pp. 251-263
-
-
Izawa, O.1
Katsuki, M.2
Komatsu, T.3
Iida, S.4
-
19
-
-
0032727438
-
Simultaneous monitoring of argatroban and its major metabolite using an HPLC method: Potential clinical applications
-
Ahmad S, Ahsan A, George M, Iqbal O, Jeske WP, McKenna R, Lewis BE, Walenga JM, Fareed J: Simultaneous monitoring of argatroban and its major metabolite using an HPLC method: Potential clinical applications. Clin Appl Thromb/Hemost 1999;5:252-258.
-
(1999)
Clin Appl Thromb/Hemost
, vol.5
, pp. 252-258
-
-
Ahmad, S.1
Ahsan, A.2
George, M.3
Iqbal, O.4
Jeske, W.P.5
McKenna, R.6
Lewis, B.E.7
Walenga, J.M.8
Fareed, J.9
-
20
-
-
0036507937
-
Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with HIT
-
Walenga JM, Ahmad S, Hoppensteadt D, Iqbal O, Hursting MJ, Lewis BE: Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with HIT. Thromb Res 2002;105:401-405.
-
(2002)
Thromb Res
, vol.105
, pp. 401-405
-
-
Walenga, J.M.1
Ahmad, S.2
Hoppensteadt, D.3
Iqbal, O.4
Hursting, M.J.5
Lewis, B.E.6
-
21
-
-
0025757180
-
Combined administration of aspirin and a specific thrombin inhibitor in man
-
Clark RJ, Mayo G, Fitzgerald GA, Fitzgerald DJ: Combined administration of aspirin and a specific thrombin inhibitor in man. Circulation 1991;83:1510-1518.
-
(1991)
Circulation
, vol.83
, pp. 1510-1518
-
-
Clark, R.J.1
Mayo, G.2
Fitzgerald, G.A.3
Fitzgerald, D.J.4
-
22
-
-
0032765276
-
Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban
-
Tran JQ, DiCicco RA, Sheth SB: Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban. J Clin Pharmacol 1999;39: 513-519.
-
(1999)
J Clin Pharmacol
, vol.39
, pp. 513-519
-
-
Tran, J.Q.1
DiCicco, R.A.2
Sheth, S.B.3
-
23
-
-
0036628640
-
Investigation of interaction between argatroban and acetamin-ophen, lidocaine, or digoxin
-
Inglis AL, Sheth SB, Hursting MJ, Tenero DM, Graham AM, DiCicco RA: Investigation of interaction between argatroban and acetamin-ophen, lidocaine, or digoxin. Am J Health Syst Pharm 2002;59:1258-1266.
-
(2002)
Am J Health Syst Pharm
, vol.59
, pp. 1258-1266
-
-
Inglis, A.L.1
Sheth, S.B.2
Hursting, M.J.3
Tenero, D.M.4
Graham, A.M.5
DiCicco, R.A.6
-
24
-
-
0032897631
-
Coagulation laboratory testing in patients treated with argatroban
-
Walenga JM, Fasanella AR, Iqbal O, Hoppensteadt DA, Ahmad S, Wallis DE, Bakhos M: Coagulation laboratory testing in patients treated with argatroban. Semin Thromb Hemost 1999;25(suppl 1):61-66.
-
(1999)
Semin Thromb Hemost
, vol.25
, Issue.1 SUPPL.
, pp. 61-66
-
-
Walenga, J.M.1
Fasanella, A.R.2
Iqbal, O.3
Hoppensteadt, D.A.4
Ahmad, S.5
Wallis, D.E.6
Bakhos, M.7
-
25
-
-
0035082406
-
Interpreting the International Normalized Ratio in individuals receiving argatroban and warfarin
-
Sheth SB, DiCicco RA, Hursting MJ, Montague T, Jorkasky DK: Interpreting the International Normalized Ratio in individuals receiving argatroban and warfarin. Thromb Haemost 2001;85:435-440.
-
(2001)
Thromb Haemost
, vol.85
, pp. 435-440
-
-
Sheth, S.B.1
DiCicco, R.A.2
Hursting, M.J.3
Montague, T.4
Jorkasky, D.K.5
-
26
-
-
0032913117
-
The International Normalized Ratio during concurrent warfarin and argatroban anticoagulation: Differential contributions of each agent and effects of the choice of thromboplastin used
-
Hursting MJ, Zehnder JL, Joffrion JL, Becker JC, Knappenberger GD, Schwarz RP: The International Normalized Ratio during concurrent warfarin and argatroban anticoagulation: Differential contributions of each agent and effects of the choice of thromboplastin used. Clin Chem 1999;45,409-412.
-
(1999)
Clin Chem
, vol.45
, pp. 409-412
-
-
Hursting, M.J.1
Zehnder, J.L.2
Joffrion, J.L.3
Becker, J.C.4
Knappenberger, G.D.5
Schwarz, R.P.6
-
27
-
-
0001359334
-
Successful coronary interventions performed with argatroban anticoagulation in patients with heparin-induced thrombocytopenia and thrombosis syndrome
-
Lewis BE, Ferguson JJ, Grassman ED, Fareed J, Walenga JM, Joffrion JL, Wrona L, Johnson SA, Schwarz RP, McKiernan T: Successful coronary interventions performed with argatroban anticoagulation in patients with heparin-induced thrombocytopenia and thrombosis syndrome. J Invas Cardiol 1996;8:410-417.
-
(1996)
J Invas Cardiol
, vol.8
, pp. 410-417
-
-
Lewis, B.E.1
Ferguson, J.J.2
Grassman, E.D.3
Fareed, J.4
Walenga, J.M.5
Joffrion, J.L.6
Wrona, L.7
Johnson, S.A.8
Schwarz, R.P.9
McKiernan, T.10
-
28
-
-
0035836541
-
Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia
-
Lewis BE, Wallis DE, Berkowitz SD, Matthai WH, Fareed J, Walenga JM, Bartholomew J for the ARG-911 Study Investigators: Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001; 103:1838-1843.
-
(2001)
Circulation
, vol.103
, pp. 1838-1843
-
-
Lewis, B.E.1
Wallis, D.E.2
Berkowitz, S.D.3
Matthai, W.H.4
Fareed, J.5
Walenga, J.M.6
Bartholomew, J.7
-
29
-
-
85112371380
-
Argatroban reexposure in patients with HIT
-
Lewis BE, Wallis DE, Zehnder JL, Barton JC, for the ARG-911/915/915X investigators: Argatroban reexposure in patients with HIT. Blood 2000;96(pt 1):52a.
-
(2000)
Blood
, vol.96
, Issue.1 PART
-
-
Lewis, B.E.1
Wallis, D.E.2
Zehnder, J.L.3
Barton, J.C.4
-
30
-
-
0036792725
-
Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia
-
Lewis BE, Matthai WH Jr, Cohen M, Moses JW, Hursting MJ, Leya F, ARG-216/310/311 Study Investigators: Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia. Catheter Cardiovasc Interv 2002; 57:177-184.
-
(2002)
Catheter Cardiovasc Interv
, vol.57
, pp. 177-184
-
-
Lewis, B.E.1
Matthai Jr., W.H.2
Cohen, M.3
Moses, J.W.4
Hursting, M.J.5
Leya, F.6
-
31
-
-
0010386576
-
Local delivery of argatroban using drug delivery device 'dispatch' in the prevention of restenosis following coronary angioplasty trial (40-CAT): Result of the prospective randomized pilot study
-
Itoh T, Nonogi H, Miyazaki S, Itoli A, Daikoko S: Local delivery of argatroban using drug delivery device 'dispatch' in the prevention of restenosis following coronary angioplasty trial (40-CAT): Result of the prospective randomized pilot study. Circulation 1997;96:3635.
-
(1997)
Circulation
, vol.96
, pp. 3635
-
-
Itoh, T.1
Nonogi, H.2
Miyazaki, S.3
Itoli, A.4
Daikoko, S.5
-
32
-
-
0001375675
-
Argatroban, a direct thrombin inhibitor versus heparin during and after percutaneous transluminal coronary angioplasty (PTCA)
-
Kobayashi H, Suzuki S, Sakamoto S, Matsuo T: Argatroban, a direct thrombin inhibitor versus heparin during and after percutaneous transluminal coronary angioplasty (PTCA). Thromb Haemost 1997(suppl);494.
-
(1997)
Thromb Haemost
, Issue.SUPPL.
, pp. 494
-
-
Kobayashi, H.1
Suzuki, S.2
Sakamoto, S.3
Matsuo, T.4
-
33
-
-
0029810466
-
Argatroban during percutaneous transluminal coronary angioplasty: Results of a dose-verification study
-
Herrman J-P, Suryapranata H, den Heijer P, Gabriël L, Kutryk MJB, Serruys PW: Argatroban during percutaneous transluminal coronary angioplasty: Results of a dose-verification study. J Thromb Thrombolysis 1996;3:367-375.
-
(1996)
J Thromb Thrombolysis
, vol.3
, pp. 367-375
-
-
Herrman, J.-P.1
Suryapranata, H.2
Den Heijer, P.3
Gabriël, L.4
Kutryk, M.J.B.5
Serruys, P.W.6
-
34
-
-
0031974853
-
The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome
-
Lewis BE, Rangel Y, Fareed J: The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome. Angiology 1998;49:61-67.
-
(1998)
Angiology
, vol.49
, pp. 61-67
-
-
Lewis, B.E.1
Rangel, Y.2
Fareed, J.3
-
36
-
-
0031419066
-
Effect of the thrombin inhibitor argatroban in acute cerebral thrombosis
-
Kobayashi S, Tazaki Y: Effect of the thrombin inhibitor argatroban in acute cerebral thrombosis. Sem Thromb Hemost 1997;23:531-534.
-
(1997)
Sem Thromb Hemost
, vol.23
, pp. 531-534
-
-
Kobayashi, S.1
Tazaki, Y.2
-
37
-
-
0027457174
-
Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris
-
Gold HK, Torres FW, Garabedian HD, Werner W, Jang IK, Khan A, Hagstrom JN, for the study investigators: Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris. J Am Coll Cardiol 1993;21:1039-1047.
-
(1993)
J Am Coll Cardiol
, vol.21
, pp. 1039-1047
-
-
Gold, H.K.1
Torres, F.W.2
Garabedian, H.D.3
Werner, W.4
Jang, I.K.5
Khan, A.6
Hagstrom, J.N.7
-
38
-
-
0000270291
-
Effect of thrombin inhibition on patients with peripheral arterial obstructive disease: A multicenter clinical trial of argatroban
-
Matsuo T, Kario K, Matsuda S, Yamaguchi N, Kakishita E: Effect of thrombin inhibition on patients with peripheral arterial obstructive disease: A multicenter clinical trial of argatroban. J Thromb Thrombolysis 1995;2:131-136.
-
(1995)
J Thromb Thrombolysis
, vol.2
, pp. 131-136
-
-
Matsuo, T.1
Kario, K.2
Matsuda, S.3
Yamaguchi, N.4
Kakishita, E.5
-
39
-
-
0032694598
-
A multicenter, randomized study of argatroban versus heparin as adjunct to TPA in acute myocardial infarction: Myocardial infarction with Novastan and TPA (MINT) trial
-
Jang I-K, Brown DF, Giugliano RP, Anderson HV, Losordo D, Nicolau JC, Dutra OP and the MINT investigators: A multicenter, randomized study of argatroban versus heparin as adjunct to TPA in acute myocardial infarction: Myocardial infarction with Novastan and TPA (MINT) trial. J Am Coll Cardiol 1999;33: 1879-1885.
-
(1999)
J Am Coll Cardiol
, vol.33
, pp. 1879-1885
-
-
Jang, I.-K.1
Brown, D.F.2
Giugliano, R.P.3
Anderson, H.V.4
Losordo, D.5
Nicolau, J.C.6
Dutra, O.P.7
-
40
-
-
17744378555
-
Argatroban and alteplase in patients with acute myocardial infarction: The ARGAMI study
-
Vermeer F, Vahanian A, Fels P, Besse P, Muller E, van de Werf F, Fitzgerald D, Darius H, Puel J, Garrigou D, Simoons ML: Argatroban and alteplase in patients with acute myocardial infarction: The ARGAMI study. J Thromb Thrombolysis 2000;10:233-240.
-
(2000)
J Thromb Thrombolysis
, vol.10
, pp. 233-240
-
-
Vermeer, F.1
Vahanian, A.2
Fels, P.3
Besse, P.4
Muller, E.5
Van De Werf, F.6
Fitzgerald, D.7
Darius, H.8
Puel, J.9
Garrigou, D.10
Simoons, M.L.11
-
41
-
-
0023709275
-
Effect of synthetic thrombin inhibitor (MD805) as an alternative drug on HIT during hemodialysis
-
Matsuo T, Chikahira Y, Yamada T, Nakao K, Ueshima S, Matsuo O: Effect of synthetic thrombin inhibitor (MD805) as an alternative drug on HIT during hemodialysis. Thromb Res 1988;52:165-171.
-
(1988)
Thromb Res
, vol.52
, pp. 165-171
-
-
Matsuo, T.1
Chikahira, Y.2
Yamada, T.3
Nakao, K.4
Ueshima, S.5
Matsuo, O.6
-
42
-
-
0028848622
-
Anticoagulation for HIT with spontaneous platelet aggregation in a patient requiring haemodialysis
-
Koide M, Yamamoto S, Matsuo M, Suzuki S, Arima N, Matsuo T: Anticoagulation for HIT with spontaneous platelet aggregation in a patient requiring haemodialysis. Nephrol Dial Transplant 1995;10:2137-2140.
-
(1995)
Nephrol Dial Transplant
, vol.10
, pp. 2137-2140
-
-
Koide, M.1
Yamamoto, S.2
Matsuo, M.3
Suzuki, S.4
Arima, N.5
Matsuo, T.6
-
43
-
-
0034307370
-
Antihirudin antibodies in patients with HIT treated with lepirudin: Incidence, effects on aPTT, and clinical relevance
-
Eichler P, Friesen H-J, Lubenow N, Jaeger B, Greinacher A: Antihirudin antibodies in patients with HIT treated with lepirudin: Incidence, effects on aPTT, and clinical relevance. Blood 2000;96:2373-2378.
-
(2000)
Blood
, vol.96
, pp. 2373-2378
-
-
Eichler, P.1
Friesen, H.-J.2
Lubenow, N.3
Jaeger, B.4
Greinacher, A.5
|