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Volumn 20, Issue 11, 2003, Pages 1804-1811

Hypoxanthine Transport in Human Glioblastoma Cells and Effect on Cell Susceptibility to Methotrexate

Author keywords

Glioblastoma; Hypoxanthine; Methotrexate; Nucleobase transport; Nucleoside transporters

Indexed keywords

HYPOXANTHINE; METHOTREXATE; URIDINE;

EID: 0344946092     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000003378.16802.97     Document Type: Article
Times cited : (5)

References (30)
  • 1
    • 0030606020 scopus 로고    scopus 로고
    • Nucleoside and nucleobase transport systems of mammalian cells
    • D. A. Griffith and S. M. Jarvis. Nucleoside and nucleobase transport systems of mammalian cells. Biochim. Biophys. Acta 1286: 153-181 (1996).
    • (1996) Biochim. Biophys. Acta , vol.1286 , pp. 153-181
    • Griffith, D.A.1    Jarvis, S.M.2
  • 2
    • 0033136943 scopus 로고    scopus 로고
    • Nucleoside transporters: Molecular biology and implications for therapeutic development
    • S. A. Baldwin, J. R. Mackey, C. E. Cass, and J. D. Young. Nucleoside transporters: molecular biology and implications for therapeutic development. Mol. Med. Today 5:216-224 (1999).
    • (1999) Mol. Med. Today , vol.5 , pp. 216-224
    • Baldwin, S.A.1    Mackey, J.R.2    Cass, C.E.3    Young, J.D.4
  • 3
    • 0030902661 scopus 로고    scopus 로고
    • Resistance to chemotherapeutic antimetabolites: A function of salvage pathway involvement and cellular response to DNA damage
    • A. R. Kinsella, D. Smith, and M. Pickard. Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage. Br. J. Cancer 75:935-945 (1997).
    • (1997) Br. J. Cancer , vol.75 , pp. 935-945
    • Kinsella, A.R.1    Smith, D.2    Pickard, M.3
  • 4
    • 0025900338 scopus 로고
    • Nucleoside salvage and resistance to antimetabolite anticancer agents
    • M. Fox, J. M. Boyle, and A. R. Kinsella. Nucleoside salvage and resistance to antimetabolite anticancer agents. Br. J. Cancer 64: 428-436 (1991).
    • (1991) Br. J. Cancer , vol.64 , pp. 428-436
    • Fox, M.1    Boyle, J.M.2    Kinsella, A.R.3
  • 6
    • 0030657927 scopus 로고    scopus 로고
    • Selective potentiation of lometrexol growth inhibition by dipyridamole through cell-specific inhibition of hypoxanthine salvage
    • R. N. Turner, G. W. Aherne, and N. J. Curtin. Selective potentiation of lometrexol growth inhibition by dipyridamole through cell-specific inhibition of hypoxanthine salvage. Br. J. Cancer 76: 1300-1307 (1997).
    • (1997) Br. J. Cancer , vol.76 , pp. 1300-1307
    • Turner, R.N.1    Aherne, G.W.2    Curtin, N.J.3
  • 7
    • 0034783030 scopus 로고    scopus 로고
    • In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate anti-folate activity
    • P. G. Smith, H. D. Thomas, H. C. Barlow, R. J. Griffin, B. T. Golding, A. H. Calvert, D. R. Newell, and N. J. Curtin. In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate anti-folate activity. Clin. Cancer Res. 7:2105-2113 (2001).
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2105-2113
    • Smith, P.G.1    Thomas, H.D.2    Barlow, H.C.3    Griffin, R.J.4    Golding, B.T.5    Calvert, A.H.6    Newell, D.R.7    Curtin, N.J.8
  • 10
    • 0023924092 scopus 로고
    • Purine nucleobase transport in human erythrocytes. Reinvestigation with a novel 'inhibitor-stop' assay
    • B. A. Domin, W. B. Mahony, and T. P. Zimmerman. Purine nucleobase transport in human erythrocytes. Reinvestigation with a novel 'inhibitor-stop' assay. J. Biol. Chem. 263:9276-9284 (1988).
    • (1988) J. Biol. Chem. , vol.263 , pp. 9276-9284
    • Domin, B.A.1    Mahony, W.B.2    Zimmerman, T.P.3
  • 11
    • 0027182514 scopus 로고
    • High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1)
    • D. A. Griffith and S. M. Jarvis. High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1). J. Biol. Chem. 268:20085-20090 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 20085-20090
    • Griffith, D.A.1    Jarvis, S.M.2
  • 12
    • 0032922413 scopus 로고    scopus 로고
    • Nucleobase transport in opossum kidney epithelial cells and Xenopus laevis oocytes: The characterisation, structure-activity relationship of uracil analogues and oocyte expression studies of sodium-dependent and -independent hypoxanthine uptake
    • M. Shayeghi, R. Akerman, and S. M. Jarvis. Nucleobase transport in opossum kidney epithelial cells and Xenopus laevis oocytes: the characterisation, structure-activity relationship of uracil analogues and oocyte expression studies of sodium-dependent and -independent hypoxanthine uptake. Biochim Biophys Acta 1416:109-118 (1999).
    • (1999) Biochim Biophys Acta , vol.1416 , pp. 109-118
    • Shayeghi, M.1    Akerman, R.2    Jarvis, S.M.3
  • 13
    • 0029121411 scopus 로고
    • +-dependent nucleobase transporter with broad substrate selectivity
    • +-dependent nucleobase transporter with broad substrate selectivity. J. Biol. Chem. 270:22816-22819 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 22816-22819
    • Washington, C.B.1    Giacomini, K.M.2
  • 14
    • 0037067704 scopus 로고    scopus 로고
    • Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation
    • S. Y. Yao, A. M. Ng, M. F. Vickers, M. Sundaram, C. E. Cass, S. A. Baldwin, and J. D. Young. Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation. J. Biol. Chem. 277:24938-24948 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 24938-24948
    • Yao, S.Y.1    Ng, A.M.2    Vickers, M.F.3    Sundaram, M.4    Cass, C.E.5    Baldwin, S.A.6    Young, J.D.7
  • 15
    • 0345425248 scopus 로고    scopus 로고
    • Brain nucleic acids
    • S. Kumar (ed.), Pergamon Press, New York
    • P. MacDonnell, K. Huff, L. Grouse, and G. Guroff. Brain nucleic acids. In S. Kumar (ed.), Biochemistry of Brain, Pergamon Press, New York, 1980, pp. 211-240.
    • Biochemistry of Brain , vol.1980 , pp. 211-240
    • MacDonnell, P.1    Huff, K.2    Grouse, L.3    Guroff, G.4
  • 16
    • 0023855577 scopus 로고
    • Hypoxanthine transport and metabolism in the central nervous system
    • R. Spector. Hypoxanthine transport and metabolism in the central nervous system. J. Neurochem. 50:969-978 (1988).
    • (1988) J. Neurochem. , vol.50 , pp. 969-978
    • Spector, R.1
  • 17
    • 0024834082 scopus 로고
    • Hypoxanthine and xanthine transport through the blood-brain barrier in hypoxanthine phosphoribosyltransferase (HPRT) deficiency
    • M. L. Jimenez, J. G. Puig, F. A. Mateos, T. H. Ramos, I. P. Castroviejo, and J. O. Vazquez. Hypoxanthine and xanthine transport through the blood-brain barrier in hypoxanthine phosphoribosyltransferase (HPRT) deficiency. Adv. Exp. Med. Biol. 173-179 (1989).
    • (1989) Adv. Exp. Med. Biol. , pp. 173-179
    • Jimenez, M.L.1    Puig, J.G.2    Mateos, F.A.3    Ramos, T.H.4    Castroviejo, I.P.5    Vazquez, J.O.6
  • 18
    • 0024491932 scopus 로고
    • Significance of purine salvage in circumventing the action of antimetabolites in rat hepatoma cells
    • Y. Natsumeda, T. Ikegami, E. Olah, and G. Weber. Significance of purine salvage in circumventing the action of antimetabolites in rat hepatoma cells. Cancer Res. 49:88-92 (1989).
    • (1989) Cancer Res. , vol.49 , pp. 88-92
    • Natsumeda, Y.1    Ikegami, T.2    Olah, E.3    Weber, G.4
  • 19
    • 0035865185 scopus 로고    scopus 로고
    • Hypoxanthine transport in human tumour cell lines: Relationship to the inhibition of hypoxanthine rescue by dipyridamole
    • E. Marshman, G. A. Taylor, H. D. Thomas, D. R. Newell, and N. J. Curtin. Hypoxanthine transport in human tumour cell lines: relationship to the inhibition of hypoxanthine rescue by dipyridamole. Biochem. Pharmacol. 61:477-484 (2001).
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 477-484
    • Marshman, E.1    Taylor, G.A.2    Thomas, H.D.3    Newell, D.R.4    Curtin, N.J.5
  • 20
    • 0034842285 scopus 로고    scopus 로고
    • Epidemiology of central nervous system tumors in childhood and adolescence based on the new WHO classification
    • C. H. Rickert and W. Paulus. Epidemiology of central nervous system tumors in childhood and adolescence based on the new WHO classification. Childs Nerv. Syst. 17:503-511 (2001).
    • (2001) Childs Nerv. Syst. , vol.17 , pp. 503-511
    • Rickert, C.H.1    Paulus, W.2
  • 23
    • 0027281788 scopus 로고
    • The chemotherapy of adult primary brain tumors
    • G. J. Lesser and S. A. Grossman. The chemotherapy of adult primary brain tumors. Cancer Treat. Rev. 19:261-281 (1993).
    • (1993) Cancer Treat. Rev. , vol.19 , pp. 261-281
    • Lesser, G.J.1    Grossman, S.A.2
  • 24
    • 0036674313 scopus 로고    scopus 로고
    • Differential chemosensitivity in human intracerebral gliomas measured by flow cytometric DNA analysis
    • Y. Iwadate, S. Fujimoto, and A. Yamaura. Differential chemosensitivity in human intracerebral gliomas measured by flow cytometric DNA analysis. Int. J. Mol. Med. 10:187-192 (2002).
    • (2002) Int. J. Mol. Med. , vol.10 , pp. 187-192
    • Iwadate, Y.1    Fujimoto, S.2    Yamaura, A.3
  • 26
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • I. Vermes, C. Haanen, H. Steffens-Nakken, and C. Reutelingsperger. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J. Immunol. Methods 184:39-51 (1995).
    • (1995) J. Immunol. Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 27
    • 0033822355 scopus 로고    scopus 로고
    • Purine uptake and release in rat C6 glioma cells: Nucleoside transport and purine metabolism under ATP-depleting conditions
    • C. J. Sinclair, C. G. LaRiviere, J. D. Young, C. E. Cass, S. A. Baldwin, and F. E. Parkinson. Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions. J. Neurochem. 75:1528-1538 (2000).
    • (2000) J. Neurochem. , vol.75 , pp. 1528-1538
    • Sinclair, C.J.1    LaRiviere, C.G.2    Young, J.D.3    Cass, C.E.4    Baldwin, S.A.5    Parkinson, F.E.6
  • 28
    • 0032937240 scopus 로고    scopus 로고
    • Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines
    • P. G. Smith, E. Marshman, A. H. Calvert, D. R. Newell, and N. J. Curtin. Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines. Semin. Oncol. 26(2 Suppl 6):63-67 (1999).
    • (1999) Semin. Oncol. , vol.26 , Issue.2 SUPPL. 6 , pp. 63-67
    • Smith, P.G.1    Marshman, E.2    Calvert, A.H.3    Newell, D.R.4    Curtin, N.J.5
  • 29
    • 0032528186 scopus 로고    scopus 로고
    • Immunosuppressive properties of methotrexate: Apoptosis and clonal deletion of activated peripheral T cells
    • L. Genestier, R. Paillot, S. Fournel, C. Ferraro, P. Miossec, and J. P. Revillard. Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. J. Clin. Invest. 102:322-328 (1998).
    • (1998) J. Clin. Invest. , vol.102 , pp. 322-328
    • Genestier, L.1    Paillot, R.2    Fournel, S.3    Ferraro, C.4    Miossec, P.5    Revillard, J.P.6
  • 30
    • 0033990959 scopus 로고    scopus 로고
    • Maintenance of differential methotrexate toxicity between cells expressing drug-resistant and wild-type dihydrofolate reductase activities in the presence of nucleosides through nucleoside transport inhibition
    • C. A. Warlick, C. L. Sweeney, and R. S. McIvor. Maintenance of differential methotrexate toxicity between cells expressing drug-resistant and wild-type dihydrofolate reductase activities in the presence of nucleosides through nucleoside transport inhibition. Biochem. Pharmacol. 59:141-151 (2000).
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 141-151
    • Warlick, C.A.1    Sweeney, C.L.2    McIvor, R.S.3


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