Multiple daily injections of NZB/W mice with LiCl leads to the long-term survival of a high percentage (80%) of the animals

Journal of Trace and Microprobe Techniques

Volumn 15, Issue 2, 1997, Pages 219-227

  Hart, David A ^a   Lenz, Steven P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Li and autoimmune disease; Li and NZB W mice; Li and renal disease; Murine SLE

Indexed keywords

EID: 0344891169     PISSN: 07334680     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Corman LC (1985) The role of diet in animal models of systemic lupus erythematosus: possible implications for human disease. Semin. Arthritis Rheum. 15, 61-69.
2. Done SJ, Lenz SP, Benediktsson H, Fritzler MJ, Martin L, Krause G, Zhao P, Hart DA (1994) The effect of lithium on murine models of lupus nephritis. Lab. Invest. 7, 156A.
3. Hart DA, Done SJ, Benediktsson H, Lenz SP (1994) Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride. Int. J. Immunopharmacol. 16, 825-833.
4. Hart DA, Lenz SP (1993) Lithium chloride treatment of BXSB male mice decreases survival in this murine model of SLE: possible role for gender-dependent variables. Lithium 3, 139-141.
5. Hart DA, Zhao P, Lenz SP, Martin L, Fritzler MJ, Done SJ, Benediktsson H, Krause G (1993) Lithium treatment of MRL-lpr mice alters disease progression in this murine model of systemic lupus erythematosus. Lithium 4, 61-68.
6. Hart DA, Lenz SP (1997) Influence of gender and timing of initiation of treatment on LiCl enhancement of NZB/W survival. J. Trace Microprobe Techniques 15, 93-99.
7. Horrobin DF (1990) Effects of lithium on essential fatty acid and prostaglandin metabolism. In: Lithium and Cell Physiology, RO Bach and VS Gallicchio eds., Springer-Verlag, New York, pp. 137-149.
8. Johnson FN (1984) The History of Lithium Therapy. MacMillan Press, London.
9. Krause G, Zhao P, Martin L, Fritzler MJ, Benediktsson H, Hart DA (1992) LiCl prolongs survival and alters disease progression in the NZB/W model of SLE. Lithium 3, 61-67.
10. Lenz SP, Izui S, Benediktsson H Hart DA (1995) LiCl enhances survival of NZB/W mice: influence of melatonin and timing of treatment. Int. J. Immunopharmacol. 17, 581-592.
11. Lenz SP, Izui S, Hart (1997) Evidence that lithium chloride treatment of female NZB/W mice does not influence autoantibody profiles in this murine model of systemic lupus erythematosus. J. Trace Microprobe Techniques 15, 109-116.
12. Lenz SP, Hart DA (1997) LiCl treatment of female NZB/W mice leads to alterations in gene expression in renal tissue. J. Trace Microprobe Techniques 15, 117-125.
13. Perrild H, Feldt-Rasmussen U, Hegedus L, Baastrup PC (1988) Serum thyroglobulin and thyroid volume during administration of lithium carbonate to healthy young subjects. In: Lithium: Inorganic Pharmacology and Psychiatric Use. NJ Birch ed., IRL Press, Oxford, pp. 183-184.
14. Perrild H, Hegedus L, Arnung K (1984) Sex related goitrogenic effect of lithium carbonate in healthy young subjects. Acta Endocrinol. (Copenhagen) 106, 203-208.
15. Reeves WH, Lahita RG (1987) Clinical presentation of systemic lupus erythematosus in the adult. In: Systemic Lupus Erythematosus, RG Lahita ed., John Wiley and sons, New York, pp. 355-382.
16. Theofilopoulos AN, Dixon FJ (1987) Experimental murine systemic lupus erythematosus. In: Systemic Lupus Erythematosus. RG Lahita ed., John Wiley and sons, New York, pp. 121-202.
17. Wallace DJ, Dubois EL (ed) (1987) Dubois' Systemic Lupus Erythematosus, Lea & Fefiger, Philadelphia.