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Volumn 4, Issue 2, 1998, Pages 167-180

Genetic interaction between U6 snRNA and the first intron nucleotide in Saccharomyces cerevisiae

Author keywords

Pre mRNA processing; Saccharomyces cerevisiae; Splice site selection; Splicing catalysis

Indexed keywords

BETA GALACTOSIDASE; MESSENGER RNA PRECURSOR; NUCLEOTIDE; SMALL NUCLEAR RNA;

EID: 0344878878     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (66)
  • 1
    • 0028273768 scopus 로고
    • The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition
    • Abovich N, Liao XC, Rosbash M. 1994. The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes & Dev 3:843-854.
    • (1994) Genes & Dev , vol.3 , pp. 843-854
    • Abovich, N.1    Liao, X.C.2    Rosbash, M.3
  • 2
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging and interactions in the yeast commitment complex are conserved in mammals
    • Abovich N, Rosbash M. 1997. Cross-intron bridging and interactions in the yeast commitment complex are conserved in mammals. Cell 89:403-412.
    • (1997) Cell , vol.89 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 3
    • 0023658298 scopus 로고
    • 5′ Cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU
    • Aebi M, Hornig H, Weissmann C. 1987. 5′ Cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU. Cell 50:237-246.
    • (1987) Cell , vol.50 , pp. 237-246
    • Aebi, M.1    Hornig, H.2    Weissmann, C.3
  • 4
    • 0030696675 scopus 로고    scopus 로고
    • The splicing factor BBP interacts specifically with the pre-mRNA branch point sequence UACUAAC
    • Berglund J, Chua K, Abovich N, Reed R, Rosbash M. 1997. The splicing factor BBP interacts specifically with the pre-mRNA branch point sequence UACUAAC. Cell 89:781-787.
    • (1997) Cell , vol.89 , pp. 781-787
    • Berglund, J.1    Chua, K.2    Abovich, N.3    Reed, R.4    Rosbash, M.5
  • 5
    • 0023782352 scopus 로고
    • Spliceosomal RNA U6 is remarkably conserved from yeast to mammals
    • Brow DA, Guthrie C. 1988. Spliceosomal RNA U6 is remarkably conserved from yeast to mammals. Nature 334:213-218.
    • (1988) Nature , vol.334 , pp. 213-218
    • Brow, D.A.1    Guthrie, C.2
  • 6
    • 0025233806 scopus 로고
    • A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing
    • Burgess S, Couto JR, Guthrie C. 1990. A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing. Cell 60:705-717.
    • (1990) Cell , vol.60 , pp. 705-717
    • Burgess, S.1    Couto, J.R.2    Guthrie, C.3
  • 7
    • 0027287852 scopus 로고
    • A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
    • Burgess SM, Guthrie C. 1993. A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell 73:1377-1391.
    • (1993) Cell , vol.73 , pp. 1377-1391
    • Burgess, S.M.1    Guthrie, C.2
  • 8
    • 0022552726 scopus 로고
    • The generality of self splicing RNA: Relationship to nuclear mRNA splicing
    • Cech T. 1986. The generality of self splicing RNA: Relationship to nuclear mRNA splicing. Cell 44:207-210.
    • (1986) Cell , vol.44 , pp. 207-210
    • Cech, T.1
  • 9
    • 0028260851 scopus 로고
    • Interaction between the first and last nucleotides of pre-mRNA introns is a determinant of 3' splice site selection in S. cerevisiae
    • Chanfreau G, Legrain P, Dujon B, Jacquier A. 1994. Interaction between the first and last nucleotides of pre-mRNA introns is a determinant of 3' splice site selection in S. cerevisiae. Nucleic Acids Res 22:1981-1987.
    • (1994) Nucleic Acids Res , vol.22 , pp. 1981-1987
    • Chanfreau, G.1    Legrain, P.2    Dujon, B.3    Jacquier, A.4
  • 10
    • 0029089334 scopus 로고
    • A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing
    • Crispino JD, Sharp PA. 1995. A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing. Genes & Dev 9:2314-2323.
    • (1995) Genes & Dev , vol.9 , pp. 2314-2323
    • Crispino, J.D.1    Sharp, P.A.2
  • 11
    • 0027327318 scopus 로고
    • The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiae
    • Datta B, Weiner AM. 1993. The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiae. Mol Cell Biol 13:5377-5382.
    • (1993) Mol Cell Biol , vol.13 , pp. 5377-5382
    • Datta, B.1    Weiner, A.M.2
  • 12
    • 0025001918 scopus 로고
    • Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing
    • Fabrizio P, Abelson J. 1990. Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing. Science 250:404-409.
    • (1990) Science , vol.250 , pp. 404-409
    • Fabrizio, P.1    Abelson, J.2
  • 13
    • 0026654005 scopus 로고
    • Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro
    • Fabrizio P, Abelson J. 1992. Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro. Nucleic Acids Res 20:3659-3664.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3659-3664
    • Fabrizio, P.1    Abelson, J.2
  • 14
    • 0022519436 scopus 로고
    • Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicing
    • Fouser L, Friesen J. 1986. Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicing. Cell 45:81-93.
    • (1986) Cell , vol.45 , pp. 81-93
    • Fouser, L.1    Friesen, J.2
  • 15
    • 0025787954 scopus 로고
    • Biochemical mechanisms of constitutive and regulated pre-mRNA splicing
    • Green MR. 1991. Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu Rev Cell Biol 7:559-599.
    • (1991) Annu Rev Cell Biol , vol.7 , pp. 559-599
    • Green, M.R.1
  • 16
    • 0026423013 scopus 로고
    • Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein
    • Guthrie C. 1991. Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein. Science 253:157-163.
    • (1991) Science , vol.253 , pp. 157-163
    • Guthrie, C.1
  • 17
    • 0020529962 scopus 로고
    • Transformation of intact yeast cells treated with alkali cations
    • Ito H, Fukada Y, Murata K, Kimura A. 1983. Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153:163-168.
    • (1983) J Bacteriol , vol.153 , pp. 163-168
    • Ito, H.1    Fukada, Y.2    Murata, K.3    Kimura, A.4
  • 18
    • 0022348855 scopus 로고
    • A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing
    • Jacquier A, Rodriguez JR, Rosbash M. 1985. A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing. Cell 43:423-430.
    • (1985) Cell , vol.43 , pp. 423-430
    • Jacquier, A.1    Rodriguez, J.R.2    Rosbash, M.3
  • 19
    • 0022524414 scopus 로고
    • RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point
    • Jacquier A, Rosbash M. 1986. RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point. Proc Natl Acad Sci USA 83:5835-5839.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5835-5839
    • Jacquier, A.1    Rosbash, M.2
  • 20
    • 0027923620 scopus 로고
    • Involvement of U6 snRNA in 5′ splice site selection
    • Kandels-Lewis S, Séraphin B. 1993. Involvement of U6 snRNA in 5′ splice site selection. Science 262:2035-2039.
    • (1993) Science , vol.262 , pp. 2035-2039
    • Kandels-Lewis, S.1    Séraphin, B.2
  • 21
    • 0002690513 scopus 로고    scopus 로고
    • Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5′ splice site
    • Kim H, Abelson J. 1996. Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5′ splice site. RNA 2:995-1010.
    • (1996) RNA , vol.2 , pp. 995-1010
    • Kim, H.1    Abelson, J.2
  • 22
    • 0030943760 scopus 로고    scopus 로고
    • Site-specific deoxynucleotide substitutions in yeast U6 snRNA block splicing of pre-mRNA in vitro
    • Kim K, Ryan D, Marciniec T, Abelson J. 1997. Site-specific deoxynucleotide substitutions in yeast U6 snRNA block splicing of pre-mRNA in vitro. EMBO J 16:2119-2129.
    • (1997) EMBO J , vol.16 , pp. 2119-2129
    • Kim, K.1    Ryan, D.2    Marciniec, T.3    Abelson, J.4
  • 23
    • 0026668641 scopus 로고
    • Purification of splicing factor SF1, a heat stable protein that functions in the assembly of a presplicing complex
    • Kramer A. 1992. Purification of splicing factor SF1, a heat stable protein that functions in the assembly of a presplicing complex. Mol Cell Biol 12:4545-4552.
    • (1992) Mol Cell Biol , vol.12 , pp. 4545-4552
    • Kramer, A.1
  • 24
    • 0027739852 scopus 로고
    • Mutations in U6 snRNA that alter splice site specificity: Implications for the active site
    • Lesser CF, Guthrie C. 1993. Mutations in U6 snRNA that alter splice site specificity: Implications for the active site. Science 262:1982-1988.
    • (1993) Science , vol.262 , pp. 1982-1988
    • Lesser, C.F.1    Guthrie, C.2
  • 25
    • 0029958501 scopus 로고    scopus 로고
    • A spontaneous duplication in U6 spliceosomal RNA uncouples the early and late functions of the ACAGA element in vivo
    • Li Z, Brow D. 1996. A spontaneous duplication in U6 spliceosomal RNA uncouples the early and late functions of the ACAGA element in vivo. RNA 2:789-794.
    • (1996) RNA , vol.2 , pp. 789-794
    • Li, Z.1    Brow, D.2
  • 26
    • 1842330298 scopus 로고    scopus 로고
    • The role of branchpoint-3′ splice site spacing and interaction between intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae
    • Luukkonen B, Seraphin B. 1997. The role of branchpoint-3′ splice site spacing and interaction between intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae. EMBO J 16:779-792.
    • (1997) EMBO J , vol.16 , pp. 779-792
    • Luukkonen, B.1    Seraphin, B.2
  • 27
    • 0028630680 scopus 로고
    • The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs
    • Lygerou Z, Conesa C, Lesage P, Swanson R, Ruet A, Carlson M, Sentenac A, Séraphin B. 1994. The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs. Nucleic Acids Res 22:5332-5340.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5332-5340
    • Lygerou, Z.1    Conesa, C.2    Lesage, P.3    Swanson, R.4    Ruet, A.5    Carlson, M.6    Sentenac, A.7    Séraphin, B.8
  • 28
    • 0025681699 scopus 로고
    • Multiple roles for U6 snRNA in the splicing pathway
    • Madhani HD, Bordonne R, Guthrie C. 1990. Multiple roles for U6 snRNA in the splicing pathway. Genes & Dev 4:2264-2277.
    • (1990) Genes & Dev , vol.4 , pp. 2264-2277
    • Madhani, H.D.1    Bordonne, R.2    Guthrie, C.3
  • 29
    • 0026486883 scopus 로고
    • A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome
    • Madhani HD, Guthrie C. 1992. A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome. Cell 71:803-817.
    • (1992) Cell , vol.71 , pp. 803-817
    • Madhani, H.D.1    Guthrie, C.2
  • 30
    • 0028556367 scopus 로고
    • Dynamic RNA-RNA interactions in the spliceosome
    • Madhani HD, Guthrie C. 1994a. Dynamic RNA-RNA interactions in the spliceosome. Ann Rev Genet 28:1-26.
    • (1994) Ann Rev Genet , vol.28 , pp. 1-26
    • Madhani, H.D.1    Guthrie, C.2
  • 31
    • 0028175201 scopus 로고
    • Randomization-selection analysis of snRNAs in vivo: Evidence for a tertiary interaction in the spliceosome
    • Madhani HD, Guthrie C. 1994b. Randomization-selection analysis of snRNAs in vivo: Evidence for a tertiary interaction in the spliceosome. Genes & Dev 8:1071-1086.
    • (1994) Genes & Dev , vol.8 , pp. 1071-1086
    • Madhani, H.D.1    Guthrie, C.2
  • 32
    • 0029959586 scopus 로고    scopus 로고
    • Interactions of the yeast U6 RNA with the pre-mRNA branch site
    • McPheeters D. 1996. Interactions of the yeast U6 RNA with the pre-mRNA branch site. RNA 2:1110-1123.
    • (1996) RNA , vol.2 , pp. 1110-1123
    • McPheeters, D.1
  • 33
    • 0001877802 scopus 로고
    • Splicing of precursors to mRNA by the spliceosome
    • Gesteland R, Atkins J, eds. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • Moore M, Query C, Sharp P. 1993. Splicing of precursors to mRNA by the spliceosome. In: Gesteland R, Atkins J, eds. The RNA world. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp 303-357.
    • (1993) The RNA World , pp. 303-357
    • Moore, M.1    Query, C.2    Sharp, P.3
  • 34
    • 0028341715 scopus 로고
    • Small nuclear RNAs and pre-mRNA splicing
    • Newman A. 1994. Small nuclear RNAs and pre-mRNA splicing. Curr Opin Cell Biol 6:360-367.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 360-367
    • Newman, A.1
  • 35
    • 0025857390 scopus 로고
    • Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage
    • Newman A, Norman C. 1991. Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage. Cell 65:115-123.
    • (1991) Cell , vol.65 , pp. 115-123
    • Newman, A.1    Norman, C.2
  • 36
    • 0022384478 scopus 로고
    • Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro
    • Newman AJ, Lin RJ, Cheng SC, Abelson J. 1985. Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro. Cell 42:335-344.
    • (1985) Cell , vol.42 , pp. 335-344
    • Newman, A.J.1    Lin, R.J.2    Cheng, S.C.3    Abelson, J.4
  • 37
    • 0026605043 scopus 로고
    • U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites
    • Newman AJ, Norman C. 1992. U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites. Cell 66:743-754.
    • (1992) Cell , vol.66 , pp. 743-754
    • Newman, A.J.1    Norman, C.2
  • 38
    • 0028308696 scopus 로고
    • RNA-RNA interactions in the spliceosome: Unraveling the ties that bind
    • Nilsen TW. 1994. RNA-RNA interactions in the spliceosome: Unraveling the ties that bind. Cell 78:1-4.
    • (1994) Cell , vol.78 , pp. 1-4
    • Nilsen, T.W.1
  • 39
    • 0021868427 scopus 로고
    • A point mutation in the conserved hexanucleotide at a yeast 5′ splice junction uncouples recognition, cleavage, and ligation
    • Parker R, Guthrie C. 1985. A point mutation in the conserved hexanucleotide at a yeast 5′ splice junction uncouples recognition, cleavage, and ligation. Cell 41:107-118.
    • (1985) Cell , vol.41 , pp. 107-118
    • Parker, R.1    Guthrie, C.2
  • 40
    • 0027408848 scopus 로고
    • Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron
    • Parker R, Siliciano PG. 1993. Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron. Nature 361:660-662.
    • (1993) Nature , vol.361 , pp. 660-662
    • Parker, R.1    Siliciano, P.G.2
  • 41
    • 0023663370 scopus 로고
    • Recognition of the TAC TAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA
    • Parker R, Siliciano PG, Guthrie C. 1987. Recognition of the TAC TAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA. Cell 49:229-239.
    • (1987) Cell , vol.49 , pp. 229-239
    • Parker, R.1    Siliciano, P.G.2    Guthrie, C.3
  • 42
    • 1842326159 scopus 로고    scopus 로고
    • The branch point residue is recognized during commitment complex formation prior to being bulged out of the U2 snRNA - Pre-mRNA duplex
    • Pascolo E, Seraphin B. 1997. The branch point residue is recognized during commitment complex formation prior to being bulged out of the U2 snRNA - pre-mRNA duplex. Mol Cell Biol 17:3469-3476.
    • (1997) Mol Cell Biol , vol.17 , pp. 3469-3476
    • Pascolo, E.1    Seraphin, B.2
  • 43
    • 0021832962 scopus 로고
    • mRNA splicing efficiency in yeast and the contribution of nonconserved sequences
    • Pikielny CW, Rosbash M. 1985. mRNA splicing efficiency in yeast and the contribution of nonconserved sequences. Cell 41:119-126.
    • (1985) Cell , vol.41 , pp. 119-126
    • Pikielny, C.W.1    Rosbash, M.2
  • 44
    • 0028205987 scopus 로고
    • Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model
    • Query CC, Moore MJ, Sharp PA. 1994. Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model. Genes & Dev 8:587-597.
    • (1994) Genes & Dev , vol.8 , pp. 587-597
    • Query, C.C.1    Moore, M.J.2    Sharp, P.A.3
  • 45
    • 0029827836 scopus 로고    scopus 로고
    • The canonical GU dinucleotide at the 5′ splice site is recognized by p220 of the U5 snRNP within the spliceosome
    • Reyes J, Kois P, Konforti B, Konarska M. 1996. The canonical GU dinucleotide at the 5′ splice site is recognized by p220 of the U5 snRNP within the spliceosome. RNA 2:213-225.
    • (1996) RNA , vol.2 , pp. 213-225
    • Reyes, J.1    Kois, P.2    Konforti, B.3    Konarska, M.4
  • 47
    • 0026453396 scopus 로고
    • Evidence for a base-pairing interaction between U6 small nuclear RNA and 5′ splice site during the splicing reaction in yeast
    • Sawa H, Abelson J. 1992. Evidence for a base-pairing interaction between U6 small nuclear RNA and 5′ splice site during the splicing reaction in yeast. Proc Natl Acad Sci USA 89:11269-11273.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11269-11273
    • Sawa, H.1    Abelson, J.2
  • 48
    • 0026524532 scopus 로고
    • Association of U6 snRNA with the 5′ splice site region of pre-mRNA in the spliceosome
    • Sawa H, Shimura Y. 1992. Association of U6 snRNA with the 5′ splice site region of pre-mRNA in the spliceosome. Genes & Dev 6:244-254.
    • (1992) Genes & Dev , vol.6 , pp. 244-254
    • Sawa, H.1    Shimura, Y.2
  • 49
    • 0029069220 scopus 로고
    • Interactions between the terminal bases of mammalian introns are retained in inosine-containing pre-mRNAs
    • Scadden ADJ, Smith CW. 1995. Interactions between the terminal bases of mammalian introns are retained in inosine-containing pre-mRNAs. EMBO J 14:3236-3246.
    • (1995) EMBO J , vol.14 , pp. 3236-3246
    • Scadden, A.D.J.1    Smith, C.W.2
  • 50
    • 0024062611 scopus 로고
    • A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site
    • Séraphin B, Kretzner L, Rosbash M. 1988. A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site. EMBO J 7:2533-2538.
    • (1988) EMBO J , vol.7 , pp. 2533-2538
    • Séraphin, B.1    Kretzner, L.2    Rosbash, M.3
  • 51
    • 0025087346 scopus 로고
    • Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing
    • Séraphin B, Rosbash M. 1990. Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing. Cell 63:619-629.
    • (1990) Cell , vol.63 , pp. 619-629
    • Séraphin, B.1    Rosbash, M.2
  • 52
    • 0025733098 scopus 로고
    • The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA
    • Séraphin B, Rosbash M. 1991. The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA. EMBO J 10:1209-1216.
    • (1991) EMBO J , vol.10 , pp. 1209-1216
    • Séraphin, B.1    Rosbash, M.2
  • 53
    • 0022131865 scopus 로고
    • On the origin of RNA splicing and introns
    • Sharp PA. 1985. On the origin of RNA splicing and introns. Cell 42:397-400.
    • (1985) Cell , vol.42 , pp. 397-400
    • Sharp, P.A.1
  • 54
    • 0024100924 scopus 로고
    • 5′ Splice site selection in yeast: Genetic alterations in base-pairing with U1 reveal additional requirements
    • Siliciano PG, Guthrie C. 1988. 5′ Splice site selection in yeast: Genetic alterations in base-pairing with U1 reveal additional requirements. Genes & Dev 2:1258-1267.
    • (1988) Genes & Dev , vol.2 , pp. 1258-1267
    • Siliciano, P.G.1    Guthrie, C.2
  • 55
    • 0027739853 scopus 로고
    • The U5 and U6 small nuclear RNAs as active site components of the spliceosome
    • Sontheimer EJ, Steitz JA. 1993. The U5 and U6 small nuclear RNAs as active site components of the spliceosome. Science 262:1989-1996.
    • (1993) Science , vol.262 , pp. 1989-1996
    • Sontheimer, E.J.1    Steitz, J.A.2
  • 56
    • 0027184481 scopus 로고
    • A general two-metal-ion mechanism for catalytic RNA
    • Steitz TA, Steitz JA. 1993. A general two-metal-ion mechanism for catalytic RNA. Proc Natl Acad Sci USA 90:6498-6502.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6498-6502
    • Steitz, T.A.1    Steitz, J.A.2
  • 57
    • 0029031713 scopus 로고
    • Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA
    • Teigelkamp S, Newman AJ, Beggs JD. 1995. Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA. EMBO J 14:2602-2612.
    • (1995) EMBO J , vol.14 , pp. 2602-2612
    • Teigelkamp, S.1    Newman, A.J.2    Beggs, J.D.3
  • 58
    • 0022747370 scopus 로고
    • Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome
    • Vijayraghavan U, Parker R, Tamm J, Iimura Y, Rossi J, Abelson J, Guthrie C. 1986. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J 5:1683-1695.
    • (1986) EMBO J , vol.5 , pp. 1683-1695
    • Vijayraghavan, U.1    Parker, R.2    Tamm, J.3    Iimura, Y.4    Rossi, J.5    Abelson, J.6    Guthrie, C.7
  • 59
    • 0026670431 scopus 로고
    • Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing
    • Wassarman DA, Steitz JA. 1992. Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing. Science 257:1918-1925.
    • (1992) Science , vol.257 , pp. 1918-1925
    • Wassarman, D.A.1    Steitz, J.A.2
  • 60
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in pre-mRNA splicing
    • Will C, Luhrmann R. 1997. Protein functions in pre-mRNA splicing. Curr Opin Cell Biol 9:320-328.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 320-328
    • Will, C.1    Luhrmann, R.2
  • 61
    • 0027979539 scopus 로고
    • Splicing function of mammalian U6 small nuclear RNA: Conserved positions in central domain and helix I are essential during the first and second step of pre-mRN a splicing
    • Wolff T, Menssen R, Hammel J, Bindereif A. 1994. Splicing function of mammalian U6 small nuclear RNA: Conserved positions in central domain and helix I are essential during the first and second step of pre-mRN A splicing. Proc Natl Acad of Sci USA 91:903-907.
    • (1994) Proc Natl Acad of Sci USA , vol.91 , pp. 903-907
    • Wolff, T.1    Menssen, R.2    Hammel, J.3    Bindereif, A.4
  • 62
    • 0024743838 scopus 로고
    • Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing
    • Wu J, Manley JL. 1989. Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes & Dev 3:1553-1561.
    • (1989) Genes & Dev , vol.3 , pp. 1553-1561
    • Wu, J.1    Manley, J.L.2
  • 63
    • 0029258858 scopus 로고
    • U6 snRNA function in nuclear pre-mRNA splicing: A phosphorothioate interference analysis of the U6 phosphate backbone
    • Yu YT, Maroney PA, Darzynkiwicz E, Nilsen TW. 1995. U6 snRNA function in nuclear pre-mRNA splicing: A phosphorothioate interference analysis of the U6 phosphate backbone. RNA 1:46-54.
    • (1995) RNA , vol.1 , pp. 46-54
    • Yu, Y.T.1    Maroney, P.A.2    Darzynkiwicz, E.3    Nilsen, T.W.4
  • 64
    • 0027145630 scopus 로고
    • Functional reconstitution of U6 snRNA in nematode cis- and trans-splicing: U6 can serve as both a branch acceptor and a 5′ exon
    • Yu YT, Maroney PA, Nilsen TW. 1993. Functional reconstitution of U6 snRNA in nematode cis- and trans-splicing: U6 can serve as both a branch acceptor and a 5′ exon. Cell 75:1049-1059.
    • (1993) Cell , vol.75 , pp. 1049-1059
    • Yu, Y.T.1    Maroney, P.A.2    Nilsen, T.W.3
  • 65
    • 0022550119 scopus 로고
    • A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation
    • Zhuang Y, Weiner AM. 1986. A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation. Cell 46:827-835.
    • (1986) Cell , vol.46 , pp. 827-835
    • Zhuang, Y.1    Weiner, A.M.2
  • 66
    • 0024744567 scopus 로고
    • A compensatory base change in human U2 snRNA can suppress a branch site mutation
    • Zhuang Y, Weiner AM. 1989. A compensatory base change in human U2 snRNA can suppress a branch site mutation. Genes & Dev 3:1545-1552.
    • (1989) Genes & Dev , vol.3 , pp. 1545-1552
    • Zhuang, Y.1    Weiner, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.