Cationic phosphoramidate α-oligonucleotides efficiently target single-stranded DNA and RNA and inhibit hepatits C virus IRES-mediated translation

Nucleic Acids Research

Volumn 31, Issue 18, 2003, Pages 5282-5290

  Michel, Thibaut ^b   Martinand Mari, Camille ^a   Debart, Françoise ^b   Lebleu, Bernard ^a   Robbins, Ian ^a   Vasseur, Jean Jacques ^b  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NUCLEOSIDE; PHOSPHORAMIDIC ACID DERIVATIVE; RIBONUCLEASE H; RNA; SINGLE STRANDED DNA;

ARTICLE; BASE MISPAIRING; BASE PAIRING; BINDING AFFINITY; CELL ASSAY; CELL CULTURE; CONTROLLED STUDY; DNA SEQUENCE; DRUG BINDING; DRUG TARGETING; ENZYME SUBSTRATE; GENETIC LINKAGE; GENETIC STABILITY; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; IONIC STRENGTH; NONHUMAN; NUCLEIC ACID STRUCTURE; PRIORITY JOURNAL; RNA HYBRIDIZATION; RNA TRANSLATION; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; THERMOSTABILITY; VIRUS INHIBITION;

AMIDES; BINDING SITES; CATIONS; CELL LINE, TUMOR; CROSS-LINKING REAGENTS; DNA, SINGLE-STRANDED; HEPACIVIRUS; HUMANS; LUCIFERASES; NUCLEIC ACID DENATURATION; NUCLEIC ACID HETERODUPLEXES; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORIC ACIDS; PROTEIN BIOSYNTHESIS; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE H, CALF THYMUS; RIBOSOMES; RNA; RNA, VIRAL; TEMPERATURE;

HEPATITIS C VIRUS; RNA VIRUSES;

EID: 0344875217     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg733     Document Type: Article

References (47)

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