Cardiovascular Hemodynamics: Relationships with Insulin Resistance in Obese Children

Pediatric Cardiology

Volumn 24, Issue 6, 2003, Pages 548-552

  Giordano, U ^a   Ciampalini, P ^a   Turchetta, A ^a   Santilli, A ^a   Calzolari, F ^a   Crino A ^a   Pompei, E ^a   Alpert, B S ^b   Calzolari, A ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Blood pressure; Cardiac output; Obesity; Systemic vascular resistance Insulin resistance

Indexed keywords

GLUCOSE; INSULIN;

ADOLESCENT; ARTICLE; CARDIOVASCULAR SYSTEM; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; EXERCISE TEST; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HEART LEFT VENTRICLE MASS; HEART OUTPUT; HEMODYNAMICS; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LINEAR REGRESSION ANALYSIS; MALE; METABOLISM; OBESITY; STATISTICAL SIGNIFICANCE; STUDENT T TEST; SYSTEMIC VASCULAR RESISTANCE; SYSTOLIC BLOOD PRESSURE;

CARDIAC OUTPUT; CASE-CONTROL STUDIES; CHILD; ECHOCARDIOGRAPHY; EXERCISE TEST; FEMALE; GLUCOSE TOLERANCE TEST; HEART VENTRICLES; HEMODYNAMIC PROCESSES; HUMANS; INSULIN RESISTANCE; LINEAR MODELS; MALE; OBESITY;

EID: 0344873800     PISSN: 01720643     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00246-003-0368-8     Document Type: Article

References (15)

1. Benetos A, Thomas F, Safar ME, Bean KE, Guize L (2001) Should diastolic and systolic blood pressure be considered for cardiovascular risk evaluation: a study in middle-aged men and women. J Am Coll Cardiol 37:163-168
2. De Simone G, Daniels SR, Devereux RB, et al. (1992) Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 20:1251-1260
3. De Simone G, Devereux RB, Daniels SR, et al. (1997) Stroke volume and cardiac output in normotensive children and adults: assessment of relations with body size and impact of overweight. Circulation 95:1837-1843
4. Harris MI (1998) Diabetes in America: epidemiology and scope of the problem. Diabetes Care 21 (suppl 3):C11-C14
5. Ilercil A, Devereux RB, Roman MJ, et al. (2001) Relationship of impaired glucose tolerance to left ventricular structure and function: The Strong Heart Study. Am Heart J 141:992-998
6. Martinez JA (2000) Obesity in young Europeans: genetic and environmental influences. Eur J Clin Nutr 54 (suppl 1):S56-S60
7. Matsuda M, DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22:1462-1470
8. Millar JA, Lever AF, Burke V (1999) Pulse pressure as a risk factor for cardiovascular events in the MRC mild hypertension trial. J Hypertens 17:1065-1072
9. Reaven GM (1998) Insulin resistance and human disease: a short history. J Basic Clin Physiol Pharmacol 9:387-406
10. Sasson Z, Rasooly Y, Bhesania T, Rasooly I (1993) Insuline resistance is an important determinant of left ventricular mass in the obese. Circulation 88:1431-1436
11. Sorof J, Daniels S (2002) Obesity hypertension in children: a problem of epidemic proportions. Hypertension 40:441-447
12. Sorof JM, Poffenbarger T, Franco K, Bernard L, Portman RJ (2002) Isolated systolic hypertension, obesity and hyperkinetic hemodynamic states in children. J Pediatr 140:643-645
13. Update on the 1987 Second Task Force Report on High Blood Pressure in Children and Adolescents: a working group report from the National High Blood Pressure Education Programme (1996) Pediatrics 98:649-658
14. Verdecchia P, Reboldi G, Schillaci G, et al. (1999) Circulating insulin and insulin growth factor-I are independent determinants of left ventricular mass and geometry in essential hypertension. Circulation 100:1802-1807
15. Zwiauer KF (2000) Prevention and treatment of overweight and obesity in children and adolescents. Eur J Pediatr 159 (suppl 1):S56-S68