Long-Term Administration of Highly Purified Eicosapentaenoic Acid Ethyl Ester Improves Blood Coagulation Abnormalities and Dysfunction of Vascular Endothelial Cells in Otsuka Long-Evans Tokushima Fatty Rats

Endocrine Journal

Volumn 50, Issue 5, 2003, Pages 603-611

  Mori, Yutaka ^a   Nobukata, Hidefumi ^b   Harada, Tsuyoshi ^b   Kasahara, Toshihiko ^b   Tajima, Naoko ^c  

^a Kawachi gun   (Japan)

^b MOCHIDA PHARMACEUTICAL CO   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Blood coagulation; Eicosapentaenoic acid ethyl ester; Otsuka Long Evans Tokushima Fatty rats; Vascular endothelial smooth muscle cells

Indexed keywords

ADENOSINE DIPHOSPHATE; ALPHA 2 ANTIPLASMIN; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; CHOLESTEROL; COLLAGEN; ICOSAPENTAENOIC ACID ETHYL ESTER; LARD; PHOSPHOLIPID; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR; PROTHROMBIN; TISSUE PLASMINOGEN ACTIVATOR; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; ENDOTHELIUM CELL; FIBRINOGEN BLOOD LEVEL; FIBRINOLYSIS; HYPERCOAGULABILITY; LONG TERM CARE; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; RAT; RAT STRAIN; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE;

ANIMALS; ARTERIES; BLOOD COAGULATION DISORDERS; CELL MOVEMENT; DRUG ADMINISTRATION SCHEDULE; EICOSAPENTAENOIC ACID; ENDOTHELIUM, VASCULAR; FIBRINOLYSIS; LIPIDS; MALE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RATS; RATS, INBRED OLETF; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 0344873276     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.50.603     Document Type: Article

References (10)

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