Glutamic acid decarboxylase (GAD)67, but not GAD65, is constitutively expressed during development and transiently overexpressed by activity in the granule cells of the rat

Neuroscience Letters

Volumn 353, Issue 1, 2003, Pages 69-71

  Maqueda, Jasmín ^a   Ramírez, Mónica ^a   Lamas, Mónica ^a,b   Gutiérrez, Rafael ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

Author keywords

Development; Glutamic acid decarboxylase; Granule cell; Mossy fibers; Seizure; Aminobutyric acid

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; ISOENZYME; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; GRANULE CELL; MOSSY FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEIZURE;

EID: 0344851617     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2003.08.077     Document Type: Article

References (19)

1. Erlander M.G., Tobin A.J. The structural and functional heterogeneity of glutamic acid decarboxylase: A review. Neurochem. Res. 16:1991;215-226.
2. Gómez-Lira G., Trillo E., Ramírez M., Asai M., Sitges M., Gutiérrez R. Expression of GABAergic transmission in the mossy fiber synapse coincides with the seizure-induced expression of GABA in mossy fiber synaptosomes. Exp. Neurol. 177:2002;276-283.
3. Gutiérrez R. Seizures induce simultaneous GABAergic and glutamatergic neurotransmission in the dentate gyrus-CA3 system. J. Neurophysiol. 84:2000;3088-3090.
4. Gutiérrez R. Activity-dependent expression of simultaneous glutamatergic and GABAergic neurotransmission from the mossy fibers in vitro. J. Neurophysiol. 87:2002;2562-2570.
5. Gutiérrez R., Heinemann U. Kindling induces transient fast inhibition in the dentate gyrus-CA3 projection. Eur. J. Neurosci. 13:2001;1371-1379.
6. Gutiérrez R., Romo-Parra H., Maqueda J., Vivar C., Ramírez M., Morales M.A., Lamas M. Plasticity of the GABAergic phenotype of the 'glutamatergic' granule cells of the rat dentate gyrus. J. Neurosci. 23:2003;5594-5598.
7. Kaufman D.L., Houser C.R., Tobin A.J. Two forms of the GABA synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. J. Neurochem. 56:1991;720-723.
8. Lamas M., Gómez-Lira G., Gutiérrez R. Vesicular GABA transporter mRNA expression in the dentate gyrus and in mossy fiber synaptosomes. Mol. Brain Res. 93:2001;209-214.
9. Lehmann H., Ebert U., Löscher W. Immunocytochemical localization of GABA immunoreactivity in dentate granule cells of normal and kindled rats. Neurosci. Lett. 212:1996;41-44.
10. Makiura Y., Suzuki F., Chevalier E., Onténiente B. Excitatory granule cells of the dentate gyrus exhibit a double inhibitory neurochemical content after intrahippocampal administration of kainate in adult mice. Exp. Neurol. 159:1999;73-83.
11. MuroCacho C.A. In situ PCR overview of procedures and applications. Front. Biosci. 2:1997;15-29.
12. Nuovo J.G. PCR In Situ Hybridization, Protocols and Applications. 1997;Lippincott Raven, Philadelphia, PA.
13. Ramírez M., Gutiérrez R. Activity-dependent expression of GAD67 in the granule cells of the rat hippocampus. Brain Res. 917:2001;139-146.
14. Romo-Parra H., Vivar C., Maqueda J., Morales M.A., Gutiérrez R. Activity-dependent induction of multitransmitter signaling onto pyramidal cells and interneurons of hippocampal area CA3. J. Neurophysiol. 89:2003;3155-3167.
15. A and α-amino-3-hidroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus. J. Biol. Chem. 275:2000;19585-19593.
16. Sandler R., Smith A.D. Coexistence of GABA and glutamate in mossy fiber terminals of the primate hippocampus: an ultrastructural study. J. Comp. Neurol. 303:1991;177-192.
17. Schwarzer C., Sperk G. Hippocampal granule cells express glutamic acid decarboxylase 67 after limbic seizures in the rat. Neuroscience. 69:1995;705-709.
18. Sloviter R.S., Dichter M.A., Rachinsky T.L., Dean E., Goodman J.H., Sollas A.L., Martin D.L. Basal expression and induction of glutamate decarboxylase and GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus. J. Comp. Neurol. 373:1996;593-618.
19. Walker M.C., Ruiz A., Kullmann D.M. Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses. Neuron. 29:2001;703-715.