Haploid male germ cells show no susceptibility to transformation by simian virus 40 large tumour antigen in transgenic mice

Cell Biology International

Volumn 22, Issue 6, 1998, Pages 437-443

  Nayernia, Karim ^a   Samani, Amir Abbas ^a   Klaproth, Silke ^a   Engel, Wolfgang ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Male germ cells; SV40 large T antigen; Transformation; Transgenic mice

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; PROACROSIN; VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA FLANKING REGION; GENE EXPRESSION REGULATION; HAPLOIDY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; ONCOGENE; RECOMBINANT GENE; REGULATOR GENE; REPORTER GENE; SIMIAN VIRUS 40; SPERMATID; TRANSGENIC MOUSE; VIRUS CELL TRANSFORMATION;

ANIMALIA; MUS MUSCULUS; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0344849480     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1998.0272     Document Type: Article

References (20)

1. AUSTIN CR, SHORT RV, 1982. Germ Cells and Fertilization in Reproduction in Mammals. Cambridge University Press, London/New York.
2. BEHRINGER RR, PESCHON JJ, MESSING A, GARTSIDE CL, HAUSCHKA SD, PALMITER RD, BRINSTER RL, 1988. Heart and bone tumors in transgenic mice. Proc Natl Acad Sci USA 85: 2648-2652.
3. BOSSE P, BERNEX F, DE SEPULVEDA P, SALAUN P, PANTHIER JJ, 1997. Multiple neuroendocrine tumors in transgenic mice induced by c-kit-SV40 T antigen fusion genes. Oncogene 14: 2661-2670.
4. BRINSTER P, CHEN HY, MESSING A, VAN DYKE T, LEVINE AJ, PALMITER RD, 1984. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37: 367-379.
5. BUEHR M, 1997. The primordial germ cells of mammals: some current perspectives. Exp Cell Res 232: 194-207.
6. FRIEDMAN NB, 1981a. The function of primordial germ cell in extragonadal tissues. Int J Andr 10: 43-49.
7. FRIEDMAN NB, VAN DE VELDE RL, 1981b. Germ cell tumors in man, pleiotropic mice and continuity of germ plasm and somatoplasm. Hum Pathol 12: 772-776.
8. HAMBURGER AW, 1977. Primary bioassay of human tumor stem cells. Science 197: 461-463.
9. HECHT NB, 1993. Cell and Molecular Biology of the Testis. Oxford University Press, New York: 400-432.
10. HOGAN B, CONSTANTINI F, LACY E, 1986. Manipulating the Mouse Embryo: a Labratory Manual. Cold Spring Harbor Labratory Press, New York.
11. MANIATIS T, FRITSCH EF, SAMBROOK J, 1982. Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
12. MCCARREY JR, 1993. Cell and Molecular Biology of the Testis. Oxford University Press, New York.
13. MOSTOFI FK, PRICE EB, 1973. Atlas of Tumor Pathology. Armed Forces Institute of Pathology Press, Washington D.C.
14. NAYERNIA K, BURKHARDT E, BEIMESCHE S, KEIME S, ENGEL W, 1992. Germ cell-specific expression of a proacrosin-CAT fusion gene in transgenic mouse testis. Mol Reprod Dev 31: 241-248.
15. NAYERNIA K, NIETER S, KREMLING H, OBERWINKLER H, ENGEL W, 1994. Functional and molecular characterization of the transcriptional regulatory region of the proacrosin gene. J Biol Chem 269: 32,181-32,186.
16. NAYERNIA K, ADHAM I, KREMLING H, REIM K, SCHLICKER M, SCHLUTER G, ENGEL W, 1996. Stage and developmental specific gene expression during mammalian spermatogenesis. Int J Dev Biol 40: 379-383.
17. RASSOULZADEGAN M, PAQUISFLUCKLINGER V, BERTINO B, SAGE J, JASIN M, MIYAGAWA K, VAN HYNINGEN V, BESMER P, CUZIN F, 1993. Transmeiotic differentiation of male germ cells in culture. Cell 75: 997-1006.
18. REDDY VB, THIMMAPPAYA B, DHAR R, SUBRAMANIAN KN, ZAIN BS, PAN J, GHOSH PK, CELMA ML, WEISSMAN SM, 1979. The genome of simian virus 40. Science 200: 494-502.
19. THOMAS H, HANBY AM, SMITH RA, HAGGER P, PATEL K, RAIKUNALIA B, CAMPLEJOHN RS, BALKWILL FR, 1996. An inbred colony of oncogene transgenic mice: diversity of tumors and potential as a therapeutic models. Br J Cancer 73: 65-72.
20. WIKENHEISER KA, WHITESETT JA, 1997. Tumor progression and cellular differentiation of pulmonary adenocarcinomas in SV40 large T antigen transgenic mice. Am J Respir Cell Mol Biol 16: 713-723.