Glycosylation study of the major genetic variants of human α 1-acid glycoprotein and of their pharmacokinetics in the rat

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 798, Issue 2, 2003, Pages 283-294

  Hervé, Françoise ^a   D'Athis, Philippe ^b   Tremblay, Dominique ^c,e   Tillement, Jean Paul ^d   Barré, Jérôme ^d  

^a HÔPITAL FERNAND WIDAL   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c Centre Hospitalier Intercommunal ^*  (France)

^d CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

^e SANOFI   (France)

Author keywords

Genetic variants; Glycosylation; Pharmacokinetics; 1 Acid glycoprotein

Indexed keywords

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; GENES; MIXTURES; ORGANIC ACIDS; PHARMACOKINETICS; PURIFICATION; SEPARATION;

GLYCOSYLATION; IMMUNONEPHELOMETRY;

PROTEINS;

GENE PRODUCT; OROSOMUCOID;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG UPTAKE; GENETIC VARIABILITY; MALE; NEPHELOMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN GLYCOSYLATION; RAT; SUBSTITUTION REACTION;

EID: 0344845338     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2003.09.057     Document Type: Article

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