Suppression of leukocyte-enhanced cold ischemia/reperfusion injury of liver endothelium with the benzoquinone antioxidant idebenone

Clinical Biochemistry

Volumn 30, Issue 8, 1997, Pages 619-624

  Schütz, Ekkehard ^a   Wieland, Eberhard ^a   Hensel, Andrea ^a   Niedmann, Paul Dieter ^a   Dreiss, Alexandra ^a   Armstrong, Victor William ^a   Schliff Werner, Peter ^a   Oellerich, Michael ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Antioxidants; Idebenone; Neutrophils; Oxidant stress; Pig liver model; Reperfusion injury

Indexed keywords

ALPHA TOCOPHEROL; HYALURONIC ACID; IDEBENONE; NITRIC OXIDE SYNTHASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UBIDECARENONE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ISOLATED LIVER; LIPID PEROXIDATION; LIVER INJURY; LIVER PROTECTION; LIVER SINUSOID; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY; SWINE;

ANIMALS; ANTIOXIDANTS; BENZOQUINONES; COLD; DEPRESSION, CHEMICAL; ENDOTHELIUM; LEUKOCYTES; LIVER; OXIDATIVE STRESS; REPERFUSION INJURY; SWINE;

EID: 0344836057     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(97)00123-9     Document Type: Article

References (34)

1. Strasberg SM, Howard TK, Molmenti EP, Hertl M. Selection othe donor liver: risk factors for poor function after orthotopic liver transplantation. Hepatology 1994; 20: 829-38.
2. Clavien PA, Harvey PR, Straßberg SM. Preservation and reperfusion injuries in liver allografts: an overview and synthesis of current studies. Transplantation 1992; 53: 957-78.
3. Jaeschke H. Preservation injury: mechanisms, prevention and consequences. J Hepatology 1996; 25: 774-80.
4. Adkinson D, Hoellwath ME, Benoit JN, Parks DA, McCord JM, Granger DN. Role of free radicals in ischemia-reperfusion injury to the liver. Acta Physiol Scand Suppl 1986; 548: 101-7.
5. Jaeschke H, Smith CV, Mitchell JR. Reactive oxygen species and ischemia-reflow injury in isolated perfused rat liver. J Clin Invest 1988; 81: 1240-6.
6. Taki Y, Gubernatis G, Yamaoka Y, et al. Significance of arterial ketone body ratio measurement in human liver transplantation. Transplantation 1990; 49: 535-9.
7. Pollard SG, Forbes MA, Metcalfe SM, Cooper EH, Calne RY. Hyaluronic acid in the assessment of liver graft function. Transplant Proc 1990; 22: 2301-2.
8. Schütz E, Luy-Kaltefleiter M, Kaltefleiter M, et al. The value of serial determination of MEGX and hyaluronic acid early after orthotopic liver transplantation. Eur J Clin Invest 1996; 26: 907-16.
9. Potter JM, Hickman PE, Lynch SV, Henderson MW, Balderson G, Strong PW. Use of monoethylglycinexylidide as a liver function test in the liver transplant recipient. Transplantation 1993; 16: 225-31.
10. Walsh TR, Rao RN, Makowka L, Starzl TE. Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia. J Surg Res 1990; 49: 18-22.
11. Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Kupffer cell activation and endothelial cell damage after storage of rat livers: effect of reperfusion. Hepatology 1991; 13: 83-95.
12. Arii S, Monden K, Adachi Y, et al. Pathogenetic role of Kupffer cell activation in the reperfusion injury of cold-preserved liver. Transplantation 1994; 58: 1072-7.
13. Clavien PA, Camargo CA, Gorczynski R, et al. Acute reactant cytokines and neutrophil adhesion after warm ischemia in cirrhotic and noncirrhotic human livers. Hepatology 1996; 23: 1456-63.
14. Jaeschke H, Farhood A, Bautista AP, Spolarics Z, Spitzer JJ, Smith CW. Functional inactivation of neutrophils with a Mac-1 (CD11B/CD18) monoclonal antibody protects against ischemia/reperfusion injury in rat liver. Hepatology 1993; 17: 377-82.
15. Jaeschke H. Vascular oxidant stress and hepatic ischemia/reperfusion injury of the liver. Free Radic Res Commun 1991; 12: 737-43.
16. Eriksson S, Fraser JRE, Laurent TC, Pertoft H, Smerbrod B. Endothelial cells are site of uptake and degradation of hyaluronic acid in the liver. Exp Cell Res 1983; 144: 223-8.
17. Reinders ME, van Wagensveld BA, van Gulik TM. Hyaluronic acid uptake in the assessment of sinusoidal endothelial cell damage after cold storage and normothermic reperfusion of rat livers. Transpl Int 1996; 9: 446-53.
18. Adams DH, Wang L, Hubscher SG, Neuberger JM. Hepatic endothelial cells. Target in liver allograft rejection? Transplantation 1991; 51: 801-6.
19. Wieland E, Schütz E, Armstrong VW, Küthe F, Heller C, Oellerich M. Idebenone protects hepatic microsomes against oxygen radical mediated damage in organ preservation solutions. Transplantation 1995; 60: 444-51.
20. Neuhaus P, Blumhardt G. Application of an improved model for experimental studies of the liver. Int J Artif Organs 1993; 16: 729-39.
21. Schütz E, Wieland E, Heine L, et al. Acceleration of hepatocellular energy by idebenone during early reperfusion after cold preservation ameliorates heat shock protein 70 gene expression in a pig liver model. Transplantation 1997; 64: 901-7.
22. Lang JK, Packer L. Quantitative determination of vitamin E and oxidized and reduced coenzyme Q by high performance liquid chromatography with in-line ultraviolet and electrochemical detection. J Chromatogr 1987; 385: 109-17.
23. Ohkawa H, Ohishi N, Yagi M. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
24. Rapp G, Klaudiny J, Hagendorff G, Luck MR, Scheidt KH. Complete sequence of the coding region of human elongation factor-2 (EF-2) by enzymatic amplification of cDNA from human ovarian granulosa cells. Biol Chem Hoppe Seyler 1989; 370: 1071-5.
25. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-9.
26. Marsden PA, Heng HH, Scherer SW, et al. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 1993; 268: 17478-88.
27. Förster E. An improved general method to generate internal standards for competitive PCR. Biotechniques 1994; 16: 18-9.
28. Chehadeh HE, Zerlauth G, Mannhalter JW. Video image analysis of quantitative competitive PCR products: Comparison of different methods. Biotechniques 1995; 18: 26-8.
29. Siebert PD, Larrick JW. Competitive PCR. Nature 1992; 359: 557-8.
30. Grace P. Ischemia-reperfusion injury. Br J Surg 1994; 81: 637-47.
31. Brass CA, Nunes F, Nagpal R. Increased oxyradical production during reoxygenation of perfused rat liver. Signal versus injury. Transplantation 1994; 57: 1329-35.
32. Sumimoto K, Matsura T, Oku JI, Fukada Y, Yamda K, Dohi K. Protective effect of UW solution on postischemic injury in rat liver. Transplantation 1996; 62: 1391-8.
33. Zhang JX, Jones DV, Clemens MG. Effect of activation of neutrophil-induced hepatic microvascular injury in isolated rat liver. Shock 1994; 1: 273-8.
34. Vollmar B, Glasz J, Leiderer R, Post S, Menger MD. Hepatic microcircular perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion. Am J Pathol 1994; 145: 1421-31.