Synthesis and evaluation of tritium labelled 10-methylgalanthamine iodide: A novel compound to examine the mechanism of interaction of galanthamine derivatives with the nicotinic acetylcholine receptors

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 46, Issue 12, 2003, Pages 1117-1125

  Schildan, Andreas ^a,b   Schirrmacher, Ralf ^a   Schirrmacher, Esther ^a   Samochocki, Marek ^a   Christner, Claudia ^a   Maelicke, Alfred ^a   Rösch, Frank ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Acetylcholinesterase inhibitor (AChE I); Allosterically potentiating ligand (APL); Galanthamine; Nicotinic acetylcholine receptor (nAChR); Tritium

Indexed keywords

CHELATION; ELECTRIC FIELDS; ELECTROPHYSIOLOGY; PHASE SEPARATION; TRITIUM;

ACETYLCHOLINE RECEPTOR; ACETYLCHOLINESTERASE INHIBITOR; ACETYLCHOLINESTERASE INHIBITORS; ALLOSTERICALLY POTENTIATING LIGAND; BINDING STUDIES; GALANTHAMINE; METHYL IODIDE; NICOTINIC ACETYLCHOLINE; NICOTINIC ACETYLCHOLINE RECEPTOR; SYNTHESISED;

LIGANDS;

10 METHYLGALANTHAMINE IODIDE H 3; GALANTAMINE; METHYL IODIDE; NICOTINIC RECEPTOR; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; ISOTOPE LABELING; RADIOCHEMISTRY; SOLID PHASE EXTRACTION;

DISCOPYGE OMMATA; TORPEDO;

EID: 0344823799     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.744     Document Type: Article

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