Actin organization associated with the expression of multidrug resistant phenotype in osteosarcoma cells and the effect of actin depolymerization on drug resistance

Cancer Letters

Volumn 126, Issue 1, 1998, Pages 75-81

  Takeshita, Hideyuki ^a,b   Kusuzaki, Katsuyuki ^a   Ashihara, Tsukasa ^a   Gebhardt, Mark C ^c   Mankin, Henry J ^c   Hirasawa, Yasusuke ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Otsu Municipal Hospital   (Japan)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Differentiation; Microfilament; Multidrug resistance; Osteosarcoma; P glycoprotein

Indexed keywords

ACTIN; DIHYDROCYTOCHALASIN B; DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOPLASM; DEPOLYMERIZATION; DRUG ACCUMULATION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; OSTEOSARCOMA CELL; PHENOTYPE; PRIORITY JOURNAL;

ANIMALIA;

EID: 0344784431     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00539-9     Document Type: Article

References (20)

1. Kartner N., Riordan J.R., Ling V. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science. 221:1983;1285-1287.
2. Fojo A.T., Ueda K., Slamon D.J., Poplack D.G., Gottesman M.M., Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc. Natl. Acad. Sci. USA. 84:1987;265-269.
3. Baldini N., Scotlandi K., Barbanti-Brodano G., Manara M.C., Maurici D., Bacci G., Bertoni F., Picci P., Sottili S., Campanacci M., Serra M. P-Glycoprotein expression and outcome in high grade osteosarcoma. N. Engl. J. Med. 333:1995;1380-1385.
4. Chan H.S.L., Haddad G., Thorner P.S., DeBoer G., Lin U.P., Ondrusek N., Yeger H., Ling V. P-Glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N. Engl. J. Med. 325:1991;1608-1614.
5. Chan H.S.L., Thorner P.S., Haddad G., Gallie B.L., Ling V. Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood. J. Clin. Oncol. 8:1990;689-704.
6. Biedler J.L. Drug resistance: genotype versus phenotype - Thirty-Second GHA Clowes Memorial Award Lecture. Cancer Res. 54:1994;666-678.
7. Biedler J.L., Spengler B.A. Reverse transformation of multidrug-resistant cells. Cancer Metastasis Rev. 13:1994;191-207.
8. H. Takeshita, M.C. Gebhardt, D.S. Springfield, P. Kloen, C. Jennings, H.J. Mankin, Biological characterization of a newly developed adriamycin-resistant murine osteosarcoma cell line, in: J.F. Novak, J.H. McMaster (Eds.), Frontiers of Osteosarcoma Research. Interdisciplinary Survey of Clinical and Research Advances, Hogfere & Hurber, Seattle, WA, 1993, pp. 239-241, 550.
9. H. Takeshita, M.C. Gebhardt, D.S. Springfield, K. Kusuzaki, H.J. Mankin, Experimental models for the study of drug resistance in osteosarcoma; P-glycoprotein-positive murine osteosarcoma cell lines. J. Bone Joint Surg. 78-A (1996) 366-375.
10. Bell R.S., Roth Y.F., Gebhardt M.C., Bell D.F., Rosenberg A.E., Mankin H.J., Suit H.D. Timing of chemotherapy and surgery in a murine osteosarcoma model. Cancer Res. 48:1988;5533-5538.
11. Wulf E., Deboben A., Bautz F.A., Faulstich H., Wieland Th. Fluorescent pallotoxin, a tool for the visualization of cellular actin. Proc. Natl. Acad. Sci. USA. 76:1979;4498-4502.
12. Hansen M.B., Nielsen S.E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods. 119:1989;203-210.
13. Turuo T., Iida H. Effects of cytochalasins and colchisine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. Biochem. Pharmacol. 35:1982;1087-1090.
14. Jung C.Y., Rampal A.L. Cytochalasin B binding sites and glucose transport carrier in human erythrocyte ghosts. J. Biol. Chem. 252:1977;5456-5463.
15. Yahara I., Harada F., Sekita S., Yoshihira K., Natori S. Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro. J. Cell Biol. 92:1982;69-82.
16. Pollack R., Osborn M., Weber K. Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc. Natl. Acad. Sci. USA. 72:1975;994-998.
17. Mickerley L.A., Bates A.S.E., Richert N.D., Currier S., Tanaka S., Foss F., Rosen N., Fojo A.T. Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. J. Biol. Chem. 264:1989;18031-18040.
18. Scotlandi K., Serra M., Manara M.C., Lollini P.-L., Maurici D., Bafalo D., Baldini N. Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin. Int. J. Cancer. 58:1994;95-101.
19. Cordon-Cardo C., O'Brien J.P., Boccia J., Casals D., Bertino J.R., Melamed M.R. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 8:1990;1277-1287.
20. van Kalken C.K., van der Valk P., Hadisaputro M.M.N., Pieters R., Broxterman H.J., Kuiper C.M., Scheffer G.L., Veerman A.J.P., Meyer C.J.L., Scheper R.J., Pinedo H.M. Differentiation dependent expression of P-glycoprotein in the normal and neoplastic human kidney. Ann. Oncol. 2:1991;55-62.