Promiscuity, pre-coupling and instability: Stabilization of active receptor states by G proteins produces effector-dependent agonist pharmacology [3] (multiple letters)

Trends in Pharmacological Sciences

Volumn 19, Issue 1, 1998, Pages 13-

  Leff, Paul ^a   Scaramellini, Clare ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

AGONIST; DRUG POTENCY; EQUILIBRIUM CONSTANT; LETTER; MOLECULAR STABILITY; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; THERMODYNAMICS;

EID: 0344784408     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(97)01150-4     Document Type: Article

References (2)

1. Leff P. et al. Trends Pharmacol. Sci. 18:1997;355-362.
2. Gethert U. et al. J. Biol. Chem. 272:1997;2587-2590.