Modified absorptive and secretory processes in the rat distal colon after neutron irradiation: In vivo and in vitro studies

Radiation Research

Volumn 151, Issue 4, 1999, Pages 468-478

  François, Agnès ^a   Dublineau, Isabelle ^a   Lebrun, Fabienne ^a   Ksas, Brigitte ^a   Griffiths, Nina M ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MYELOPEROXIDASE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON ABSORPTION; COLON DISEASE; COLON MUCOSA; COLON SECRETION; CONTROLLED STUDY; MALE; NEUTRON RADIATION; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; RAT; WHOLE BODY RADIATION;

ANIMALS; COLON; ELECTRIC STIMULATION; ELECTROLYTES; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MALE; NEUTRONS; NITRIC OXIDE SYNTHASE; PEROXIDASE; RATS; RATS, WISTAR; SEROTONIN;

ANIMALIA;

EID: 0344780710     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579835     Document Type: Article

References (45)

1. K. R. Trott and T. Herrmann, Radiation effects on abdominal organs. In Radiopathology of Organs and Tissues (E. Scherer, C. Streffer and K. R. Trott, Eds.), pp. 313-346. Springer Verlag, Berlin, 1991.
2. A. Danielsson, H. Nyhlin, H. Persson, U. Stendahl, R. Stenling and O. Suhr, Chronic diarrhea after radiotherapy for gynecological cancer: Occurrence and etiology. Gut 32, 1180-1187 (1991).
3. E. Yeoh, M. Horowitz, A. Russo, T. Muecke, T. Robb, A. Maddox and B. Chatterton, Effect of pelvic irradiation on gastrointestinal function: A prospective longitudinal study. Am. J. Med. 95, 397-406 (1993).
4. P. J. Gunter-Smith, The effect of radiation on intestinal electrolyte transport. In Radiation and the Gastrointestinal Tract (A. Dubois, G. L. King and D. R. Livengood, Eds.), pp. 149-160. CRC Press, Boca Raton, FL, 1995.
5. M. F. Otterson, T. R. Koch, Z. Zhang, S. C. Leming and J. E. Moulder, Fractionated irradiation alters enteric neuroendocrine products. Dig. Dis. Sci. 40, 1691-1702 (1995).
6. N. M. Griffiths, A. François, I. Dublineau, F. Lebrun, C. Joubert, J. Aigueperse and P. Gourmelon, Exposure to either gamma or a mixed neutron/gamma field irradiation modifies vasoactive intestinal peptide receptor characteristics in membranes isolated from pig jejunum. Int. J. Radiat. Biol. 70, 361-370 (1996).
7. V. Esposito, C. Linard, C. Maubert, J. Aigueperse and P. Gourmelon, Modulation of gut substance P after whole body irradiation: A new pathological feature. Dig. Dis. Sci. 41, 2070-2077 (1996).
8. K. L. Jackson, R. Rhodes and C. Entenman, Electrolyte excretion in the rat after severe intestinal damage by X-irradiation. Radiat. Res. 8, 361-373 (1958).
9. P. F. Curran, E. W. Webster and J. Housepian, The effect of X-irradiation on sodium and water transport in rat ileum. Radiat. Res. 13, 369-380 (1960).
10. W. K. MacNaughton, K. E. Leach, L. Prud'homme-Lalonde, W. Ho and K. Sharkey, Ionizing radiation reduces neurally-evoked electrolyte transport in rat ileum through a mast cell-dependent mechanism. Gastroenterology 105, 1651-1661 (1994).
11. J. J. Battermann, G. A. M. Hact and K. Breur, Dose-effect relations for tumor control and complication rate after fast neutron therapy for pelvic tumors. Br. J. Radiol. 54, 899-904 (1981).
12. N. Breiter, P. Kneschaurek, G. Burger, J. Huczkowski and K. R. Trott, The r.b.e. of fast fission neutrons (2 MeV) for chronic radiation damage of the large bowel of rats after single dose and fractionated irradiation. Int. J. Radiat. Biol. 49, 1031-1038 (1986).
13. S. G. Wilson, Radiation-induced gastrointestinal death in the monkey. Am. J. Pathol. 35, 1233-1251 (1959).
14. K. C. Pedley and R. J. Naftalin, Evidence from fluorescence microscopy and comparative studies that rat, ovine and bovine colonic crypts are absorptive. J. Physiol. 460, 525-547 (1993).
15. M. J. Welsh, P. L. Smith, M. Fromm and R. A. Frizzell, Crypts are the site of intestinal fluid and electrolyte secretion. Science 218, 1219-1221 (1982).
16. D. Bleakman and R. J. Naftalin, Hypertonic fluid in rabbit descending colon in vitro. Am. J. Physiol. 258, G377-G380 (1990).
17. S. K. Singh, H. J. Binder, W. F. Boron and J. P. Grebel, Fluid absorption in isolated perfused colonic crypts. J. Clin. Invest. 96, 2373-2379 (1995).
18. - secretion via Plexus Meissner and amiloride-sensitive electrogenic Na-absorption is not affected by intramural neurons. Pflügers Arch. 414, 216-221 (1989).
19. K. A. Hubel, The effect of electrical field stimulation and tetrodotoxin on ion transport by the isolated rabbit ileum. J. Clin. Invest. 62, 1039-1047 (1978).
20. M. D. Gershon, P. R. Wade, A. L. Kirchgessner and H. Tamir, 5-HT receptor subtypes outside the central nervous system. Roles in the physiology of the gut. Neuropsychopharmacology 3, 385-395 (1990).
21. L. Oosterbosch, M. Von Der Ohe, M. A. Valdovinos, L. J. Kost, S. F. Phillips and M. Camilleri, Effects of serotonin on rat ileocolic transit and fluid transfer in vivo: Possible mechanisms of action. Gut 34, 794-798 (1993).
22. A. Siriwardena, C. Booker, J. Pratt and J. M. Kellum, Pathways of serotonin-induced electrolyte transport in rat distal colon. Surgery 110, 411-417 (1991).
23. E. Beubler and A. Schirgi-Degen, Serotonin antagonists inhibit sennoside-induced fluid secretion and diarrhea. Pharmacology 47 (Suppl. 1), 64-69 (1993).
24. N. Kishihayashi, Y. Miwa, H. Hayashi, A. Ishii, S. Ichikawa, H. Nonaka, T. Yokoyama and F. Suzuki, 5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome. J. Med. Chem. 36, 3286-3292 (1993).
25. R. Medioni and H. J. Delafield, Reactor and reference dosimetry of radiation fields. In An International Intercomparison of Criticality Accident Dosimetry Systems at the SILENE Reactor (R. Medioni and H. J. Delafield, Eds.). AEA Technology, Didcot, UK, 1995.
26. + flux of varying luminal hydraulic resistance in rat colon in vivo. J. Physiol. 477, 539-548 (1994).
27. I. Dublineau, B. Ksas, J. Aigueperse, P. Gourmelon and N. M. Griffiths, In vivo alterations of fluid and electrolyte fluxes in rat colon by gamma irradiation. Dig. Dis. Sci. 43, 652-662 (1998).
28. M. Fromm and U. Hegel, Segmental heterogeneity of epithelial transport in rat large intestine. Pflügers Arch. 378, 71-83 (1978).
29. A. François, J. Aigueperse, P. Gourmelon, W. K. MacNaughton and N. M. Griffiths, Exposure to ionizing radiation modifies neurally-evoked electrolyte transport and some inflammatory responses in rat colon in vitro. Int. J. Radiat. Biol. 73, 93-101 (1998).
30. G. Curzon and A. R. Green, Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain. Br. J. Pharmacol. 39, 653-655 (1970).
31. J. E. Krawisz, P. Sharon and W. F. Stenson, Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology 87, 1344-1350 (1984).
32. 2+-independent nitric oxide synthases. FEBS Lett. 291, 145-149 (1991).
33. H. R. Withers and K. A. Mason, The kinetics of recovery in irradiated colonic mucosa of the mouse. Cancer 34, 896-903 (1974).
34. F. Hirose, Early effects of 14.1 MeV neutron irradiation on intestinal mucosa. In Gastrointestinal Radiation Injury (M. F. Sullivan, Ed.), pp. 327-330. Excerpta Medica, New York, 1968.
35. S. Hornsey and S. Vatistas, Gut leakage and intestinal death as a measure of radiation damage: RBE values for neutrons and the effects of fractionation. In Gastrointestinal Radiation Injury (M. F. Sullivan, Ed.), pp. 396-400. Excerpta Medica, New York, 1968.
36. V. M. Rajendran and H. J. Binder, Ion transport in rat colon. Adv. Comp. Environ. Physiol. 16, 113-137 (1993).
37. J. Harris and R. Shields, Absorption and secretion of water and electrolytes by the intact human colon in diffuse untreated proctocolitis. Gut 11, 27-33 (1970).
38. W. K. MacNaughton, K. E. Leach, L. Prud'homme-Lalonde and R. K. Harding, Exposure to ionizing radiation increases responsiveness to neural secretory stimuli in the ferret jejunum in vitro. Int. J. Radiat. Biol. 72, 219-226 (1997).
39. D. D. Metcalfe, D. Baram and Y. A. Mekori, Mast cells. Physiol. Rev. 77, 1033-1079 (1997).
40. S. E. Crowe, G. K. Luthra and M. H. Perdue, Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease. Gut 41, 785-792 (1997).
41. J. L. Wallace, A. Higa, G. W. McKnight and D. E. MacIntyre, Prevention and reversal of experimental colitis by a monoclonal antibody which inhibits leukocyte adherence. Inflammation 16, 343-354 (1992).
42. M. G. Buell and R. K. Harding, Proinflammatory effects of local abdominal irradiation on rat gastrointestinal tract. Dig. Dis. Sci. 34, 390-399 (1989).
43. F. Hirose and M. Wake, Acute effects of 14.1 MeV neutron irradiation on the hematopoietic organ in rats. J. Radiat. Res. 7, 146-166 (1966).
44. I. Alican and P. Kubes, A critical role for nitric oxide in intestinal function and dysfunction. Am. J. Physiol. 270, G225-G237 (1996).
45. K. E. Carr, S. P. Hume, A. C. Nelson, O. O'Shea, R. A. Hazzard and J. S. McCullough, Morphological profiles of neutron and X-irradiated small intestine. J. Radiat. Res. 37, 38-48 (1996).