Cloning and expression of human liver UDP-glucuronosyltransferase cDNA, UDPGTh2

Archives of Pharmacal Research

Volumn 20, Issue 5, 1997, Pages 459-464

  Dong, Misook ^a   Owens, Ida S ^b   Sheen, Yhun Yhong ^a  

^a Ewha Womans University   (South Korea)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Tunicamycin; UDP Glucuronosyltransferase cDNA; UDPGTh2

Indexed keywords

EID: 0344765175     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02973940     Document Type: Article

References (15)

1. Bock W. K., Clausbruch U.C.V. and Ottenwalder H., UDP-glucuronosyltransferase in perfused rat liver and in microsomes. Biochem. Pharm., 27, 369-371 (1978).
2. Bock, K. W., Lilienblum, W. and Pfiel, H., Functional Heterogeneity of UDP-Glucuronosyltransferase activities in C57BL/6 and DBA/2 Mice. Biochem. Pharmacol., 31, 1273-1277 (1982).
3. Burchell B. and Blakckaert N., Bilirubin mono- and diglucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronosylransferase. Biochem. J., 223, 461-465 (1984).
4. Church, G. and Gilbert, W. J., Genomic sequencing. Proc. Natl. Acad. Sci. U.S.A., 81, 1991-1995 (1984).
5. Dutton, G. J., Glucuronidation of drugs and other compounds. CRC Inc., Florida USA pp. 69-78, 1980.
6. Fournel-Gigleux, S., Jackson, M. R., Wooster, R. and Burchell, B., Expression of a human liver cDNA encoding a UDP-glucuronosyltransferas catalysing the glucuronidation of hyodeoxycholic acid in cell culture. FEBS Lett., 243, 119-122 (1989).
7. Harding, D., Fournel-Gigleux, S., Jackson, M. R. and Burchelle, B., Cloning and Substrate Specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells. Proc. Natl. Acad. Sci. U.S. A., 85, 8381-8385 (1988).
8. Kornfeld., R. and Kornfeld. S., Assembly of asparagin-linked oligosaccharides. Ann. Rev. Bichem., 50, 555-583 (1981).
9. Jackson, M. R., McCarthy, L. R., Harding, D., Wilson, S., Coughtrie, M. W. H. and burchell, B., Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA. Biohem. J., 242, 581-588 (1987).
10. Kimura, T. and Owens I. S., Mouse UDP glucuronosyltransferase cDNA and complete amino acid sequence and regulation. Eur. J. Biochem., 168, 515-521 (1987).
11. Kirkpatrick, R. B., Falany, C. N. and Tephly, T. R., Glucuronidation of Bile Acids by Rat Liver 3-OH Androgen UDP-Glucuronosyltransferase. J. Biol. Chem., 259, 6176-6180 (1984).
12. Mackenzie, P. I., Hjelmeland, L H. and Owens, I. S., Purification and Immunochemical Characterization of a Low Form of UDP Glucuronosyltransferase from Mouse Liver. Arch. Biochem. Biophys., 231, 487-497 (1984).
13. Matern, H., Matern, S. and Gerok, W., Isolation and Characterization of rat Liver Microsomal UDP-Glucuronosyltransferase Activity toward Chenodeoxycholic Acid and Testosterone as a Single Form of Enzyme. J. Biol. Chem., 257, 7422-7429 (1982).
14. Rose, T. K., Welsch, W. J., Sefton, B. M., Esch, F. S. and Ling, N. C., Vesicular Stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus. Proc. Natl. Acad. Sci. U.S.A., 77, 3884-3888 (1980).
15. Wishhart, G. J., Functional heterogenesity of UDP-glucuronosyltransferase as indicated by its differential development and inducibility by glucocorticoid. Biochem. J., 174, 485-489 (1978).