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Volumn 26, Issue 6, 2003, Pages 322-326

Pharmacokinetics of Etilevodopa Compared to Levodopa in Patient's with Parkinson's Disease: An Open-label, Randomized, Crossover Study

Author keywords

Etilevodopa; Motor fluctuations; Pharmacokinetics

Indexed keywords

ANTIPARKINSON AGENT; APOMORPHINE; CARBIDOPA; CARBIDOPA PLUS LEVODOPA; ETILEVODOPA; LEVODOPA; UNCLASSIFIED DRUG;

EID: 0344738870     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002826-200311000-00012     Document Type: Article
Times cited : (22)

References (16)
  • 1
    • 0034905501 scopus 로고    scopus 로고
    • Motor fluctuations and dyskinesia in Parkinson's disease
    • Nutt JG. Motor fluctuations and dyskinesia in Parkinson's disease. Parkinsonism Relat Disord. 2001;8:101-108.
    • (2001) Parkinsonism Relat Disord , vol.8 , pp. 101-108
    • Nutt, J.G.1
  • 2
    • 0023762236 scopus 로고
    • Motor fluctuations in Parkinson's disease: Central pathophysiological mechanisms. Part I
    • Fabbrini G, Mouradian MM, Juncos JL, et al. Motor fluctuations in Parkinson's disease: central pathophysiological mechanisms. Part I. Ann Neurol. 1988;24:366-371.
    • (1988) Ann Neurol , vol.24 , pp. 366-371
    • Fabbrini, G.1    Mouradian, M.M.2    Juncos, J.L.3
  • 3
    • 0036587778 scopus 로고    scopus 로고
    • Role of integrative pharmacokinetic and pharmacodynamic optimization strategy in the management of Parkinson's disease patients experiencing motor fluctuations with levodopa
    • Okereke CS. Role of integrative pharmacokinetic and pharmacodynamic optimization strategy in the management of Parkinson's disease patients experiencing motor fluctuations with levodopa. J Pharm Pharm Sci. 2002;5:146-161.
    • (2002) J Pharm Pharm Sci , vol.5 , pp. 146-161
    • Okereke, C.S.1
  • 4
    • 0027930341 scopus 로고
    • Longitudinal monitoring of the levodopa concentration-effect relationship in Parkinson's disease
    • Contin M, Riva R, Martinelli P, et al. Longitudinal monitoring of the levodopa concentration-effect relationship in Parkinson's disease. Neurology. 1994;44:1287-1292.
    • (1994) Neurology , vol.44 , pp. 1287-1292
    • Contin, M.1    Riva, R.2    Martinelli, P.3
  • 5
    • 0036093898 scopus 로고    scopus 로고
    • Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease
    • Deleu D, Northway MG, Hanssens Y. Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clin Pharmacokinet. 2002;41:261-309.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 261-309
    • Deleu, D.1    Northway, M.G.2    Hanssens, Y.3
  • 6
    • 0043136666 scopus 로고    scopus 로고
    • Waiting for 'on' - A major problem in patients with Parkinson's disease and 'on-off' motor fluctuations
    • in press
    • Merims D, Djaldetti R, Melamed E. Waiting for 'on' -a major problem in patients with Parkinson's disease and 'on-off' motor fluctuations. Clin Neuropharmacol. 2003;(in press)
    • (2003) Clin Neuropharmacol
    • Merims, D.1    Djaldetti, R.2    Melamed, E.3
  • 7
    • 0015922208 scopus 로고
    • Active transport of L-dopa in the intestine
    • Wade DN, Mearrick PT, Morris JL. Active transport of L-dopa in the intestine. Nature. 1973;242:463-465.
    • (1973) Nature , vol.242 , pp. 463-465
    • Wade, D.N.1    Mearrick, P.T.2    Morris, J.L.3
  • 8
    • 0029864459 scopus 로고    scopus 로고
    • Gastric emptying in Parkinson's disease: Patients with and without response fluctuations
    • Djaldetti R, Baron J, Ziv I, et al. Gastric emptying in Parkinson's disease: patients with and without response fluctuations. Neurology. 1996;46:1051-1054.
    • (1996) Neurology , vol.46 , pp. 1051-1054
    • Djaldetti, R.1    Baron, J.2    Ziv, I.3
  • 9
    • 0035526250 scopus 로고    scopus 로고
    • Gastric emptying time and gastric motility in patients with Parkinson's disease
    • Hardoff R, Tamir A, Sula M, et al. Gastric emptying time and gastric motility in patients with Parkinson's disease. Mov Disord. 2001;16: 104-107.
    • (2001) Mov Disord , vol.16 , pp. 104-107
    • Hardoff, R.1    Tamir, A.2    Sula, M.3
  • 11
    • 0030482506 scopus 로고    scopus 로고
    • Impaired absorption of oral levodopa: A major cause for response fluctuations in Parkinson's disease
    • Djaldetti R, Ziv I, Melamed E. Impaired absorption of oral levodopa: a major cause for response fluctuations in Parkinson's disease. Isr J Med Sci. 1996;32:1224-1227.
    • (1996) Isr J Med Sci , vol.32 , pp. 1224-1227
    • Djaldetti, R.1    Ziv, I.2    Melamed, E.3
  • 12
    • 0030006032 scopus 로고    scopus 로고
    • Levodopa ethylester: A novel rescue therapy for response fluctuations in Parkinson's disease
    • Djaldetti R, Melamed E. Levodopa ethylester: a novel rescue therapy for response fluctuations in Parkinson's disease. Ann Neurol. 1996;39:400-404.
    • (1996) Ann Neurol , vol.39 , pp. 400-404
    • Djaldetti, R.1    Melamed, E.2
  • 13
    • 0004884113 scopus 로고    scopus 로고
    • Intestinal hydrolysis of TV-1203, a levodopa prodrug
    • Abstract
    • Blaugrund E, Myke A, Sayag N, et al. Intestinal hydrolysis of TV-1203, a levodopa prodrug. Parkinsonism Relat Disorder. 1999;5: S67. (Abstract)
    • (1999) Parkinsonism Relat Disorder , vol.5
    • Blaugrund, E.1    Myke, A.2    Sayag, N.3
  • 14
    • 0036523778 scopus 로고    scopus 로고
    • Oral solution of levodopa ethylester for treatment of response fluctuations in patients with advanced Parkinson's disease
    • Djaldetti R, Inzelberg R, Giladi N, et al. Oral solution of levodopa ethylester for treatment of response fluctuations in patients with advanced Parkinson's disease. Mov Disord. 2002;17:297-302.
    • (2002) Mov Disord , vol.17 , pp. 297-302
    • Djaldetti, R.1    Inzelberg, R.2    Giladi, N.3
  • 15
    • 0000018626 scopus 로고
    • Motility of the stomach and gastroduodenal function
    • Johnson IR, ed. New York: Raven Press
    • Kelly MA. Motility of the stomach and gastroduodenal function. In: Johnson IR, ed. Physiology of the gastrointestinal tract. New York: Raven Press, 1981: 393-410.
    • (1981) Physiology of the Gastrointestinal Tract , pp. 393-410
    • Kelly, M.A.1
  • 16
    • 0022451735 scopus 로고
    • The pharmacokinetics of intravenous and oral levodopa in patients with Parkinson's disease who exhibit on-off fluctuations
    • Hardie RJ, Malcolm SL, Lees AJ, et al. The pharmacokinetics of intravenous and oral levodopa in patients with Parkinson's disease who exhibit on-off fluctuations. Br J Clin Pharmacol. 1986;22:429-436.
    • (1986) Br J Clin Pharmacol , vol.22 , pp. 429-436
    • Hardie, R.J.1    Malcolm, S.L.2    Lees, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.