Cocaine induces apoptosis in cerebral vascular muscle cells: Potential roles in strokes and brain damage

European Journal of Pharmacology

Volumn 482, Issue 1-3, 2003, Pages 61-66

  Su, Jialin ^a   Li, Jianfeng ^a   Li, Wenyan ^a   Altura, Bella T ^a,b   Altura, Burtonm ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

Apoptosis; Cerebral vascular smooth muscle cell; Cocaine; Stroke

Indexed keywords

COCAINE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN NERVE CELL; CELL ASSAY; CELL CULTURE; CELL STRUCTURE; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOG; FLUORESCENCE MICROSCOPY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; STROKE; VASCULAR SMOOTH MUSCLE;

EID: 0344737714     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.09.056     Document Type: Article

References (39)

1. Altura B.M., Gupta R.K. Cocaine induces intracellular free Mg deficits, ischemia and stroke as observed by in-vivo 31P-NMR of the brain. Biochim. Biophys. Acta. 1111:1992;271-274.
2. Altura B.M., Altura B.T., Gebrewold A. Cocaine-induced spasms of cerebral blood vessels: relation to cerebral vascular accidents, strokes and hypertension. Fed. Proc. 44:1985;1637.
3. 2+ in cerebral vascular smooth muscle cells. Eur. J. Pharmacol. 246:1993;299-301.
4. Araki S., Shimada Y., Kaji K., Hayashi H. Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation. Biochem. Biophys. Res. Commun. 168:1990;1194-2000.
5. Barbour R.L., Gebrewold A., Altura B.M. Optical backscatter spectroscopy of rat brain indicates cocaine alters blood volume, hemoglobin oxygenation and mitochondrial redox state. FASEB J. 7:1993;A1076.
6. Bennett M.R., Evan G.I., Newby A.C. Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues and induces apoptosis. Circ. Res. 74:1994;525-536.
7. Bennett M.R., Littlewood T.D., Schwartz S.M., Weissberg P.L. Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaques to p53-mediated apoptosis. Circ. Res. 81:1997;591-599.
8. Cho A., Courtman D.W., Langille B.L. Apoptosis (programmed cell death) in arteries of the neonatal lamb. Circ. Res. 76:1995;168-175.
9. Daras M., Tuchman A.J., Koppel B.S., Samkoff L.M., Weitzher I., Marc J. Neurovascular complications of cocaine. Acta Neurol. Scand. 90:1994;124-129.
10. Devlin A.M., Clark J.S., Reid J.L., Dominiczak A.F. DNA synthesis and apoptosis in smooth muscle cells from a model of genetic hypertension. Hypertension. 36:2000;110-115.
11. Frederichs R.K., McQuiuen J.B. Cerebral vasculitis associated with cocaine abuse. Stroke. 22:1991;1437-1439.
12. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
13. Geng Y.J., Libby P. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. Am. J. Pathol. 147:1995;251-266.
14. Gold M.S. Drugs of Abuse: A Comprehensive Series for Clinicians. vol. 3:1993;1-10 Plenum Medical Blood, New York.
15. Han D.K., Haudenschild C.C., Hong M.K., Tinkle B.T., Leon M.B., Liau G. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am. J. Pathol. 147:1995;267-277.
16. He G.Q., Zhang A., Altura B.T., Altura B.M. Cocaine-induced cerebrovaso-spasm and its possible mechanism of action. J. Pharmacol. Exp. Ther. 268:1993;1532-1539.
17. He J., Xiao Y., Zhang L. Cocaine-mediated apoptosis in bovine coronary artery endothelial cells: role of nitric oxide. J. Pharmacol. Exp. Ther. 298:2001;180-187.
18. Hetts S.W. To die or not to die: an overview of apoptosis and its role in disease. JAMA. 279:1998;300-307.
19. 2+ in rat brain. Neurosci. Lett. 109:1990;113-116.
20. Isner J.M., Kearney M., Bortman S., Passeri J. Apoptosis in human atherosclerosis and restenosis. Circulation. 91:1995;2703-2711.
21. Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
22. Kerr J.F., Winterford C.M., Harmon B.V. Apoptosis. Its significance in cancer and cancer therapy. Cancer. 73:1994;2013-2026.
23. Li H., Xu L., Dunbar J.C., Dhabuwala C.B. Role of mitochondrial cytochrome c in cocaine-induced apoptosis in rat testes. Urology. 61:2003;646-650.
24. Mallat Z., Tedgui A. Apoptosis in the vasculature: mechanisms and functional importance. Br. J. Pharmacol. 130:2000;947-962.
25. Mangiardi J.R., Daras M., Geller M.E., Weitzner I., Tuchman A.J. Cocaine-related intracranial hemorrhage. Report of nine cases and review. Acta Neurol. Scand. 77:1988;177-180.
26. Neiman J., Haapaniemi H.M., Hillbom M. Neurological complications of drug abuse: pathophysiological mechanisms. Eur. J. Neurol. 7:2000;595-606.
27. Nolte K.B., Gelman B.B. Intracranial hemorrhage associated with cocaine abuse. Arch. Pathol. Lab. Med. 113:1989;812-813.
28. Polis A., Maginn D., Barr J.L. Tissue deposition of cocaine in man: a report of five fatal poisonings. Forensic Sci. Int. 33:1987;83-88.
29. Pollman M.J., Yamada T., Horiuchi M., Gibbons G.H. Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II. Circ. Res. 79:1996;748-756.
30. Sharan N., Chong V.Z., Nair V.D., Mishra R.K., Hayes R.J., Gardner E.L. Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions. Synapse. 47:2003;33-44.
31. Thorball N., Moe H., Winther-Nielsen H. Progressive involution and physiological death of smooth muscle cells of rat incisal arterioles. Blood Vessels. 22:1985;157-169.
32. Van Dyke C., Barash P.G., Jatlow P., Byck R. Cocaine: plasma concentrations after intranasal application in man. Science. 27:1976;859-861.
33. Wang J.F., Ren X., DeAngelis J., Min J., Zhang Y., Hampton T.G., Amende I., Morgan J.P. Differential patterns of cocaine-induced organ toxicity in murine heart versus liver. Exp. Biol. Med. (Maywood). 226:2001;52-60.
34. ++ dependent endonuclease with protein kinase C as a possible mechanism for cytokine resistance in human renal carcinoma cells. J. Urol. 155:1996;1779-1783.
35. Wu Y.B., Hagen K.L., Shen M.L., Ou D.W. Evidence of increased DNA content of murine thymocytes caused by cocaine. Immunopharmacol. Immunotoxicol. 25:2003;53-64.
36. Xiao Y., He J., Gilbert R.D., Zhang L. Cocaine induces apoptosis in fetal myocardial cells through a mitochondria-dependent pathway. J. Pharmacol. Exp. Ther. 292:2000;8-14.
37. Zhang A., Cheng T.P.O., Altura B.M. Magnesium regulates intracellular free ionized calcium concentration and cell geometry in vascular smooth muscle cells. Biochim. Biophys. Acta, Mol. Cell Res. 1134:1992;25-29.
38. Zhang A., Cheng T.P.O., Altura B.T., Altura B.M. Acute cocaine results in rapid rises in intracellular free calcium concentration in canine cerebral vascular smooth muscle cells: possible relation to etiology of stroke. Neurosci. Lett. 215:1996;57-59.
39. Zimmermann K.C., Bonzon C., Green D.R. The machinery of programmed cell death. Pharmacol. Ther. 92:2001;57-70.