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Volumn 275, Issue 5, 1998, Pages 785-794

Isolation and characterization of a Simian UDP-glucuronosyltransferase UGT2B18 active on 3-hydroxyandrogens

Author keywords

Androgen metabolism; Androsterone; Monkey; Prostate; UDP glucuronosyltransferase

Indexed keywords

ANDROGEN; ANDROSTANEDIOL; ANDROSTERONE; BILE ACID; COMPLEMENTARY DNA; ETIOCHOLANOLONE; GLUCURONOSYLTRANSFERASE; PHENOL DERIVATIVE; POLYCLONAL ANTIBODY;

EID: 0344734180     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1486     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 0029809062 scopus 로고    scopus 로고
    • Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids
    • Beaulieu, M., Lévesque, É., Hum, D. W. & Bélanger, A. (1996). Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids. J. Biol. Chem. 271, 22855-22862.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22855-22862
    • Beaulieu, M.1    Lévesque, É.2    Hum, D.W.3    Bélanger, A.4
  • 3
    • 0030669325 scopus 로고    scopus 로고
    • Expression and characterization of a novel UDP-Glucuronosyltransferase, UGT2B9, from cynomulgus monkey
    • Bélanger, G., Beaulieu, M., Lévesque, E., Hum, D. W. & Bélanger, A. (1997). Expression and characterization of a novel UDP-Glucuronosyltransferase, UGT2B9, from cynomulgus monkey. DNA Cell Biol. 16(10), 1195-1205.
    • (1997) DNA Cell Biol. , vol.16 , Issue.10 , pp. 1195-1205
    • Bélanger, G.1    Beaulieu, M.2    Lévesque, E.3    Hum, D.W.4    Bélanger, A.5
  • 4
    • 0023227144 scopus 로고
    • Increase in plasma steroid glucuronide levels in men from infancy to adulthood
    • Brochu, M. & Bélanger, A. (1987). Increase in plasma steroid glucuronide levels in men from infancy to adulthood. J. Clin. Endocrinol. Metab. 64(6), 1283-1287.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , Issue.6 , pp. 1283-1287
    • Brochu, M.1    Bélanger, A.2
  • 5
    • 0027273696 scopus 로고
    • Evidence for increased androsterone metabolism in some normoandrogenic women with acne
    • Carmina, E. & Lobo, R. A. (1993). Evidence for increased androsterone metabolism in some normoandrogenic women with acne. J. Clin. Endocrinol. Metab. 76(5), 1111-1114.
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , Issue.5 , pp. 1111-1114
    • Carmina, E.1    Lobo, R.A.2
  • 6
    • 0027373153 scopus 로고
    • Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms
    • Chen, F., Ritter, J. K., Wang, M. G., Mcbride, O. W., Lubet, R. A. & Owens, I. S. (1993). Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms. Biochemistry, 32(40), 10648-10657.
    • (1993) Biochemistry , vol.32 , Issue.40 , pp. 10648-10657
    • Chen, F.1    Ritter, J.K.2    Wang, M.G.3    Mcbride, O.W.4    Lubet, R.A.5    Owens, I.S.6
  • 7
    • 0001177611 scopus 로고
    • The uridine diphosphate glucuronosyltransferase multigene family: Function and regulation
    • (Frederic, C. K. F. C., ed.), Springler-Verlag
    • Clarke, D. J. & Burchell, B. (1994). The uridine diphosphate glucuronosyltransferase multigene family: function and regulation. In Handbook of Experimental Pharmacology (Frederic, C. K. F. C., ed.), vol. 112, pp. 3-43, Springler-Verlag.
    • (1994) Handbook of Experimental Pharmacology , vol.112 , pp. 3-43
    • Clarke, D.J.1    Burchell, B.2
  • 10
    • 0019419129 scopus 로고
    • A general, fast, and sensitive micromethod for DNA determination: Application to rat and mouse liver, rat hepatoma, human leukocytes, chicken fibroblasts, and yeast cells
    • Fiszer-Szafarz, B., Szafarz, D. & Guevara, A. (1981). A general, fast, and sensitive micromethod for DNA determination: application to rat and mouse liver, rat hepatoma, human leukocytes, chicken fibroblasts, and yeast cells. Anal. Biochem. 110, 165-170.
    • (1981) Anal. Biochem. , vol.110 , pp. 165-170
    • Fiszer-Szafarz, B.1    Szafarz, D.2    Guevara, A.3
  • 11
    • 0025447648 scopus 로고
    • The interference of arochlor 1254 with progesterone metabolism in guinea pig adrenal and testes
    • Goldman, D. & Yawetz, A. (1990). The interference of arochlor 1254 with progesterone metabolism in guinea pig adrenal and testes. J. Biochem. Toxicol. 5, 99-107.
    • (1990) J. Biochem. Toxicol. , vol.5 , pp. 99-107
    • Goldman, D.1    Yawetz, A.2
  • 12
    • 0028031001 scopus 로고
    • Stable expression of a human liver UDP-glucuronosyltransferase UGT2B15 with activity toward steroid and xenobiotic substrates
    • Green, M., Oturu, E. M. & Tephly, T. R. (1994). Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15 with activity toward steroid and xenobiotic substrates. Drug Metab. Disp. 22, 799-805.
    • (1994) Drug Metab. Disp. , vol.22 , pp. 799-805
    • Green, M.1    Oturu, E.M.2    Tephly, T.R.3
  • 13
    • 0029084012 scopus 로고
    • Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols
    • Green, M. D., Clarke, D. J., Oturu, D. J., Styczynski, P. B., Jackson, M. R., Burchell, B. & Tephly, T. R. (1995). Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols. Arch. Biochem. Biophys. 322, 460-468.
    • (1995) Arch. Biochem. Biophys. , vol.322 , pp. 460-468
    • Green, M.D.1    Clarke, D.J.2    Oturu, D.J.3    Styczynski, P.B.4    Jackson, M.R.5    Burchell, B.6    Tephly, T.R.7
  • 14
    • 0029617355 scopus 로고
    • Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two UGT enzymes
    • Guillemette, C., Hum, D. W. & Bélanger, A. (1995). Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two UGT enzymes. J. Steroid Biochem. Mol. Biol. 55, 355-362.
    • (1995) J. Steroid Biochem. Mol. Biol. , vol.55 , pp. 355-362
    • Guillemette, C.1    Hum, D.W.2    Bélanger, A.3
  • 15
    • 0029760979 scopus 로고    scopus 로고
    • Levels of plasma C19 steroids and 5α-reduced C19 steroid glucuronides in primates, rodents, and domestic animals
    • Guillemette, C., Hum, D. W. & Bélanger, A. (1996). Levels of plasma C19 steroids and 5α-reduced C19 steroid glucuronides in primates, rodents, and domestic animals. Am. J. Physiol. 271, E348-E353.
    • (1996) Am. J. Physiol. , vol.271
    • Guillemette, C.1    Hum, D.W.2    Bélanger, A.3
  • 16
    • 0030991972 scopus 로고    scopus 로고
    • Differential regulation of two UDP-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells
    • Guillemette, C., Lévesque, É., Beaulieu, M., Turgeon, D., Hum, W. D. & Bélanger, A. (1997). Differential regulation of two UDP-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells. Endocrinology, 138(7), 2998-3005.
    • (1997) Endocrinology , vol.138 , Issue.7 , pp. 2998-3005
    • Guillemette, C.1    Lévesque, É.2    Beaulieu, M.3    Turgeon, D.4    Hum, W.D.5    Bélanger, A.6
  • 17
    • 17744417608 scopus 로고
    • Nucleotide and deduced amino acid sequence of rat liver 17 beta-hydroxysteroid UDP-glucuronosyltransferase
    • Harding, D., Wilson, S. M., Jackson, M. R., Burchell, B., Green, M. D. & Tephly, T. R. (1987). Nucleotide and deduced amino acid sequence of rat liver 17 beta-hydroxysteroid UDP-glucuronosyltransferase. Nucl. Acids Res. 15(9), 3936.
    • (1987) Nucl. Acids Res. , vol.15 , Issue.9 , pp. 3936
    • Harding, D.1    Wilson, S.M.2    Jackson, M.R.3    Burchell, B.4    Green, M.D.5    Tephly, T.R.6
  • 18
    • 0026542141 scopus 로고
    • Dihydrotestosterone is a peripheral paracrine hormone
    • Horton, R. (1992). Dihydrotestosterone is a peripheral paracrine hormone. J. Androl. 13, 23-27.
    • (1992) J. Androl. , vol.13 , pp. 23-27
    • Horton, R.1
  • 19
    • 0022647532 scopus 로고
    • The full length coding sequence of rat liver androsterone UDP-glucuronyltransferase cDNA and comparison with other members of this gene family
    • Jackson, M. R. & Burchell, B. (1986). The full length coding sequence of rat liver androsterone UDP-glucuronyltransferase cDNA and comparison with other members of this gene family. Nucl. Acids Res. 14(2), 779-795.
    • (1986) Nucl. Acids Res. , vol.14 , Issue.2 , pp. 779-795
    • Jackson, M.R.1    Burchell, B.2
  • 21
    • 0027267719 scopus 로고
    • cDNA cloning and expression of 2 new members of the human liver UDP-glucuronosyltransferase-2B subfamily
    • Jin, C. J., Miners, J. O., Lillywhite, K. J. & Mackenzie, P. I. (1993). cDNA cloning and expression of 2 new members of the human liver UDP-glucuronosyltransferase-2B subfamily. Biochem. Biophys. Res. Commun. 194(1), 496-503.
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , Issue.1 , pp. 496-503
    • Jin, C.J.1    Miners, J.O.2    Lillywhite, K.J.3    Mackenzie, P.I.4
  • 22
    • 0031570313 scopus 로고    scopus 로고
    • The regio and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11
    • Jin, C. J., Mackenzie, P. I. & Miners, J. O. (1997). The regio and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11. Arch. Biochem. Biophys. 341, 207-211.
    • (1997) Arch. Biochem. Biophys. , vol.341 , pp. 207-211
    • Jin, C.J.1    Mackenzie, P.I.2    Miners, J.O.3
  • 23
    • 0023642573 scopus 로고
    • Mouse UDP glucuronosyltransferase cDNA and complete amino acid sequence and regulation
    • Kimura, T. & Owens, I. S. (1987). Mouse UDP glucuronosyltransferase cDNA and complete amino acid sequence and regulation. Eur. J. Biochem. 168, 515-521.
    • (1987) Eur. J. Biochem. , vol.168 , pp. 515-521
    • Kimura, T.1    Owens, I.S.2
  • 26
    • 0030795936 scopus 로고    scopus 로고
    • Isolation and characterization of UGT2B15(Y85): A UDP-glucuronosyltransferase encoded by a polymorphic gene
    • Lévesque, É. , Beaulieu, M., Green, M. D., Tephly, T. R., Bélanger, A. & Hum, D. W. (1997). Isolation and characterization of UGT2B15(Y85): A UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics. 7, 317-325.
    • (1997) Pharmacogenetics , vol.7 , pp. 317-325
    • Lévesque, É.1    Beaulieu, M.2    Green, M.D.3    Tephly, T.R.4    Bélanger, A.5    Hum, D.W.6
  • 27
    • 0031033883 scopus 로고    scopus 로고
    • Expression and fonctional domains of rabbit liver UDP-glucuronosyltransferase 2B16 and 2B13
    • Li, Q., Lou, X., Peyronneau, M. A., Obermayer, Straub P. & Tukey, R. H. (1997). Expression and fonctional domains of rabbit liver UDP-glucuronosyltransferase 2B16 and 2B13. J. Biol. Chem. 272, 3272-3279.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3272-3279
    • Li, Q.1    Lou, X.2    Peyronneau, M.A.3    Obermayer4    Straub, P.5    Tukey, R.H.6
  • 29
    • 0023808264 scopus 로고
    • Correlation of serum 3 alpha-androstanediol glucuronide with acne and chest hair density in men
    • Lookingbill, D. P., Egan, N., Santen, R. J. & Demers, L. M. (1988). Correlation of serum 3 alpha-androstanediol glucuronide with acne and chest hair density in men. J. Clin. Endocrinol. Metab. 67(5), 986-991.
    • (1988) J. Clin. Endocrinol. Metab. , vol.67 , Issue.5 , pp. 986-991
    • Lookingbill, D.P.1    Egan, N.2    Santen, R.J.3    Demers, L.M.4
  • 30
    • 0023031991 scopus 로고
    • Rat Liver UDP-glucuronosyltransferase cDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens
    • Mackenzie, P. I. (1986a). Rat Liver UDP-glucuronosyltransferase cDNA sequence and expression of a form glucuronidating 3-hydroxyandrogens. J. Biol. Chem. 261(30), 14112-14117.
    • (1986) J. Biol. Chem. , vol.261 , Issue.30 , pp. 14112-14117
    • Mackenzie, P.I.1
  • 31
    • 0023035858 scopus 로고
    • Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form
    • Mackenzie, P. I. (1986b). Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form. J. Biol. Chem. 261(13), 6119-6125.
    • (1986) J. Biol. Chem. , vol.261 , Issue.13 , pp. 6119-6125
    • Mackenzie, P.I.1
  • 32
    • 0023655381 scopus 로고
    • Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol
    • Mackenzie, P. I. (1987). Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol. J. Biol. Chem. 262(20), 9744-9749.
    • (1987) J. Biol. Chem. , vol.262 , Issue.20 , pp. 9744-9749
    • Mackenzie, P.I.1
  • 33
    • 0025236448 scopus 로고
    • Expression of chimeric cDNAs in cell culture defines a region of UDP glucuronosyltransferase involved in substrate selection
    • Mackenzie, P. I. (1990). Expression of chimeric cDNAs in cell culture defines a region of UDP glucuronosyltransferase involved in substrate selection. J. Biol. Chem. 265(6), 3432-3435.
    • (1990) J. Biol. Chem. , vol.265 , Issue.6 , pp. 3432-3435
    • Mackenzie, P.I.1
  • 35
  • 36
    • 0026072670 scopus 로고
    • Codon 377 polymorphism of the human type I 3β-hydroxysteroid dehydrogenase/isomerase gene (HS5DB3)
    • Rhéaume, E., Sirois, I., Labrie, F. & Simard, J. (1991). Codon 377 polymorphism of the human type I 3β-hydroxysteroid dehydrogenase/isomerase gene (HS5DB3). Nucl. Acids Res. 19, 6060.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 6060
    • Rhéaume, E.1    Sirois, I.2    Labrie, F.3    Simard, J.4
  • 37
    • 0025321169 scopus 로고
    • Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates
    • Ritter, J. K., Sheen, Y. Y. & Owens, I. S. (1990). Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates. J. Biol. Chem. 265(14), 7900-7906.
    • (1990) J. Biol. Chem. , vol.265 , Issue.14 , pp. 7900-7906
    • Ritter, J.K.1    Sheen, Y.Y.2    Owens, I.S.3
  • 38
    • 0018937308 scopus 로고
    • Vesicular stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus
    • Rose, J. K., Welch, W. J., Sefton, B. M., Esch, F. S. & Ling, N. C. (1980). Vesicular stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus. Proc. Natl Acad. Sci. USA, 77(7), 3884-3888.
    • (1980) Proc. Natl Acad. Sci. USA , vol.77 , Issue.7 , pp. 3884-3888
    • Rose, J.K.1    Welch, W.J.2    Sefton, B.M.3    Esch, F.S.4    Ling, N.C.5
  • 40
    • 0024272026 scopus 로고
    • Endogenous substrates for UDP-glucuronosyltransferases
    • Tephly, T. R., Green, M., Puig, J. & Irshaid, Y. (1988). Endogenous substrates for UDP-glucuronosyltransferases. Xenobiotica, 18, 1201-1210.
    • (1988) Xenobiotica , vol.18 , pp. 1201-1210
    • Tephly, T.R.1    Green, M.2    Puig, J.3    Irshaid, Y.4
  • 41
    • 0027179250 scopus 로고
    • Cloning and characterization of rabbit liver UDP-glucuronosyltransferase cDNAs
    • Tukey, R. H., Pendurthi, U. R., Nguyen, N. T., Green, M. D. & Tephly, T. R. (1993). Cloning and characterization of rabbit liver UDP-glucuronosyltransferase cDNAs. J. Biol. Chem. 268, 15260-15266.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15260-15266
    • Tukey, R.H.1    Pendurthi, U.R.2    Nguyen, N.T.3    Green, M.D.4    Tephly, T.R.5


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