Ototoxicity of sodium nitroprusside is not due to nitric oxide

Experimental Neurology

Volumn 158, Issue 1, 1999, Pages 192-201

  Ruan, Run Sheng ^a   Leong, Seng Kee ^b   Yeoh, Kian Hian ^a  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Acetylcysteine; Cochlea; Cyanide S nitrosocysteine; Guinea pig; Hydroxycobalamin; Nitric oxide

Indexed keywords

ACETYLCYSTEINE; CYANIDE; GELFOAM; HYDROXOCOBALAMIN; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; S NITROSOCYSTEINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; COCHLEA FENESTRA; CONTROLLED STUDY; FEMALE; GUINEA PIG; HAIR CELL; LIGHT EXPOSURE; MALE; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL;

EID: 0344690185     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7075     Document Type: Article

References (18)

1. Amaee F. R., Comis S. D., Osborne M. P., Drew S., Tarlow M. J. Possible involvement of nitric oxide in the sensorineural hearing loss of bacterial meningitis. Acta Otolaryngol. 117:1997;329-336.
2. G-nitro-L-arginine decreases cochlear blood flow. Assoc. Res. Otolaryngol. 368:1993;92.
3. Brechtelsbauer P. B., Nuttall A. L., Miller J. M. Basal nitric oxide production in the cochlear vasculature. Otolaryngol. Head Neck Surg. 111:1995;70.
4. Brown J. N., Miller J. M., Nuttall A. L. Age-related changes in cochlear vascular conductance in mice. Hear. Res. 86:1995;189-194.
5. Chen C., Nenov A., Skellett R., Fallon M., Bright L., Norris C. H., Bobbin R. P. Nitroprusside suppresses cochlear potentials and outer hair cell responses. Hear. Res. 87:1995;1-8.
6. Dais C. G., Prazma J., Ball S. S., Zdanski C., Carrasco V., Pillsbury H. C. Effect of sodium nitroprusside on compound action potential thresholds in the gerbil cochlea. Hear. Res. 99:1996;1-6.
7. Fessenden J. D., Coling D. E., Schacht J. Detection and characterization of nitric oxide synthase in the mammalian cochlea. Brain Res. 668:1994;9-15.
8. Fessenden J. D., Schacht J. Localization of soluble guanylate cyclase activity in the guinea pig cochlea suggests involvement in regulation of blood flow and supporting cell physiology. J. Histochem. Cytochem. 45:1997;1401-1408.
9. Gilman A. G., Rall T. W., Nies A. S., Taylor P. The Pharmacological Basis of Therapeutics. 1990;Pergamon, New York. p. 768.
10. He B. P., Tay S. S. W., Leong S. K. Motoneuronal death without expression of NADPH-diaphorase activity after sciatic nerve cut in five-day-old mice. Brain Res. 733:1996;125-128.
11. Kong W. J., Ren T., Nutall A. L. Electrophysiological and morphological evaluation of the acute ototoxicity of sodium nitroprusside. Hear. Res. 99:1996;22-30.
12. Lei S. Z., Pan Z.-H., Aggarwal S. K., Chen H.-S. V., Hartman J., Sucher N. J., Lipton S. A. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron. 8:1992;1087-1099.
13. Ohlsen A., Hultcrantz E., Engstrom B. The effect of topical application of vasodilation agents on cochlear electrophysiolgy. Acta. Otolaryngol. 113:1993;55-61.
14. Ohlsen K. A., Didier A., Baldwin D., Miller J. M., Nuttall A. L. Cochlear blood flow in response to dilating agents. Hear. Res. 58:1992;19-25.
15. Ren T., Nuttall A. L., Miller J. M. ATP-induced cochlear blood flow changes involve the nitric oxide pathway. Hear. Res. 112:1997;87-94.
16. Ruan R. S., Leong S. K., Yeoh K. H. Localization of nitric oxide synthase and NADPH-diaphorase in guinea pig and human cochleae. J. Brain Res. 38:1997;433-411.
17. Ruan R. S., Leong S. K., Yeoh K. H. Ototoxicity of sodium nitroprusside. Hear. Res. 114:1997;169-178.
18. Zdanski C. J., Prazma J., Petrusz P., Grossman G., Raynor E., Smith T. L., Pillsbury H. C. Nitric oxide synthase is an active enzyme in the spiral ganglion cells of the rat cochlea. Hear. Res. 79:1994;39-47.