Prolongation of nerve and epidural anesthetic blockade by bupivacaine in a lipid emulsion

Anesthesia and Analgesia

Volumn 89, Issue 1, 1999, Pages 121-127

  Lázaro, Juan J ^a   Franquelo, Carme ^a   Navarro, Xavier ^a   Castellano, Bernardo ^a   Verdú, Enrique ^a   Cristòfol, Carles ^a   Arboix, Margarita ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; LIPID EMULSION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG ELIMINATION; DRUG HALF LIFE; ELECTROPHYSIOLOGY; EPIDURAL ANESTHESIA; EPIDURAL DRUG ADMINISTRATION; FEMALE; HISTOLOGY; LATENT PERIOD; NERVE BLOCK; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL ROOT;

ANESTHESIA, EPIDURAL; ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; EMULSIONS; FEMALE; NERVE BLOCK; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TIME FACTORS;

EID: 0344689918     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199907000-00021     Document Type: Article

References (26)

1. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979;51:285-7.
2. Kloss T, van Deyk K, Hempel V. Delayed respiratory arrest following spinal anesthesia. Reg Anaesth 1984;7:98-100.
3. Reynolds F. Adverse effects of local anaesthetics. Br J Anaesth 1987;59:78-95.
4. Ready LB, Plumer MH, Haschke RH, et al. Neurotoxicity of intrathecal local anesthetics in rabbits. Anesthesiology 1985;63: 364-70.
5. Kroin JS, Penn RD, Levy FE, Kerns JM. Effect of repetitive lidocaine infusion on peripheral nerve. Exp Neurol 1986;94: 166-73.
6. Kalichman MW, Moorhouse DF, Powell HC, Myers RR. Relative neural toxicity of local anesthetics. J Neuropathol Exp Neurol 1993;52:234-40.
7. Kane RE. Neurological deficits following epidural or spinal anesthesia. Anesth Analg 1981;60:150-61.
8. Rigler ML, Drasner K, Krejcie TC, et al. Cauda equina syndrome after continuous spinal anesthesia. Anesth Analg 1991;72: 275-81.
9. Feldman HS, Covino BG. A chronic model for investigation of experimental spinal anesthesia in the dog. Anesthesiology 1981; 54:148-52.
10. Kroin JS, McCarthy RJ, Penn RD, et al. The effect of chronic subarachnoid bupivacaine infusion in dog. Anesthesiology 1987;66:737-42.
11. Durant PAC, Yaksh TL. Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study. Anesthesiology 1986; 64:43-53.
12. Mashimo T, Uchida I, Pak M, et al. Prolongation of canine epidural anesthesia by liposome encapsulation of lidocaine. Anesth Analg 1992;74:827-34.
13. Grant GJ, Vermeulen K, Langerman L, et al. Prolonged analgesia with liposomal bupivacaine in a mouse model. Reg Anesth 1994;19:264-9.
14. Planas ME, González P, Rodríguez L, et al. Noninvasive percutaneous induction of topical analgesia by a new type of drug carrier, and prolongation of local pain insensitivity by anesthetic liposomes. Anesth Analg 1992;75:615-21.
15. Langerman L, Golomb E, Benita S. Spinal anesthesia: significant prolongation of the pharmacologic effect of tetracaine with lipid solution of the agent. Anesthesiology 1991;74:105-7.
16. Langerman L, Grant GJ, Zakowski M, et al. Prolongation of spinal anesthesia: differential action of a lipid drug carrier on tetracaine, lidocaine, and procaine. Anesthesiology 1992;77: 475-81.
17. Langerman L, Grant GJ, Zakowski M, et al. Prolongation of epidural anesthesia using a lipid drug carrier with procaine, lidocaine, and tetracaine. Anesth Analg 1992;75:900-5.
18. Hassan HG, Youssef H, Renck H. Duration of experimental nerve block by combinations of local anesthetic agents. Acta Anaesthesiol Scand 1993;37:70-4.
19. Wang GK, Vladimirov M, Quan C, et al. N-butyl tetracaine as a neurolytic agent for ultralong sciatic nerve block. Anesthesiology 1996;85:1386-94.
20. Masters DB, Berde CB, Dutta SK, et al. Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix. Anesthesiology 1993;79:340-6.
21. Navarro X, Lázaro JJ, Butí M, et al. Electrophysiological evaluation of spinal reflexes during epidural anesthesia in an experimental model. Muscle Nerve 1996;19:29-36.
22. Navarro X, Verdú E, Butí M. Comparison of regenerative and reinnervating capabilities of different functional types of nerve fibers. Exp Neurol 1994;129:217-24.
23. Franquelo C, Toledo A, Manubens J, et al. Bupivacaine disposition and pharmacologic effects after intravenous and epidural administrations in dogs. Am J Vet Res 1995;56:1087-91.
24. Gissen AJ, Covino BG, Gregus J. Differential sensitivities of mammalian nerve fibers to local anesthetic agents. Anesthesiology 1980; 53:467-74.
25. Popitz-Bergez FA, Leeson S, Strichartz GR, Thalhammer JG. Relation between functional deficit and intraneural local anesthetic during peripheral nerve block. Anesthesiology 1995;83: 583-92.
26. Strichartz GR, Sánchez V, Arthur GR, et al. Fundamental properties of local anesthetics. II. Measured octanol:buffer partition coefficients and pKa values of clinically used drugs. Anesth Analg 1990;71:158-70.