Do women with epilepsy have increased frequency of menstrual disturbances?

Seizure

Volumn 12, Issue 8, 2003, Pages 529-533

  Svalheim, Sigrid ^a   Taubøll, Erik ^a   Bjørnenak, Tone ^a   Røste, Line Sveberg ^a   Mørland, Tore ^b   Sætre, Erik R ^c   Gjerstad, Leif ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b TELEMARK HOSPITAL   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Antiepileptic drugs; Epilepsy; Fertility; Menstrual disorder; Valproate; Women

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; VALPROIC ACID;

ADULT; AGE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DRUG USE; EPILEPSY; FEMALE; FREQUENCY ANALYSIS; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MENSTRUATION DISORDER; MONOTHERAPY; MORBIDITY; OUTPATIENT; PRIORITY JOURNAL; QUESTIONNAIRE; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS;

EID: 0344668636     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1059-1311(03)00195-X     Document Type: Article

References (25)

1. Pritchard, P. B. III, Wannamaker, B. B., Sagel, J., Nair, R. and DeVillier, C. Endocrine function following complex partial seizures. Annals of Neurology 1983; 14: 27-32.
2. Herzog, A. G., Seibel, M. M., Schomer, D. L., Veitukaitis, J. L. and Geschwind, N. Reproductive endocrine disorders in women with partial seizures of temporal lobe origin. Archives of Neurology 1986; 43: 341-346.
3. Bilo, L., Meo, R., Nappi, C. et al. Reproductive endocrine disorders in women with primary generalized epilepsy. Epilepsia 1988; 29: 612-619.
4. Bilo, L., Meo, R., Valentino, R., Di Carlo, C., Striano, S. and Nappi, C. Characterization of reproductive endocrine disorders in women with epilepsy. The Journal of Clinical Endocrinology and Metabolism 2001; 86: 2950-2956.
5. Morrell, M. J. The new antiepileptic drugs and women: efficacy, reproductive health, pregnancy, and fetal outcome. Epilepsia 1996; 37: 34-44.
6. Herzog, A. G. and Friedman, M. N. Menstrual cycle interval and ovulation in women with localization-related epilepsy. Neurology 2001; 57: 2133-2135.
7. Edwards, H. E., Burnham, W. M., Ng, M. M., Asa, S. and MacLusky, N. J. Limbic seizures alter reproductive function in the female rat. Epilepsia 1999; 40: 1370-1377.
8. Edwards, H. E., Burnham, W. M. and MacLusky, N. J. Partial and generalized seizures affect reproductive physiology differentially in male rat. Epilepsia 1999; 40: 1490-1498.
9. Edwards, H. E., MacLusky, N. J. and Burnham, W. M. The effect of seizures and kindling on reproductive hormones in the rat. Neuroscience and Biobehavioral Reviews 2000; 24: 753-762.
10. Mattson, R. H. and Cramer, J. A. Epilepsy, sex hormones, and antiepileptic drugs. Epilepsia 1985; 26: 40-51.
11. Isojärvi, J. I. T., Laatikainen, T. J., Pakarinen, A. J., Juntunen, K. T. and Myllylä, V. V. Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy. New England Journal of Medicine 1993; 329: 1383-1388.
12. Isojärvi, J. I. T., Laatikainen, T. J., Knip, M., Pakarinen, A. J., Juntunen, K. T. S. and Myllylä, V. V. Obesity and endocrine disorders in women taking valproate for epilepsy. Annals of Neurology 1996; 39: 579-584.
13. Bauer, J. Interactions between hormones and epilepsy in female patients. Epilepsia 2001; 42: 20-23.
14. Isojärvi, J. I. T., Taubøll, E., Tapanainen, J., Pakarinen, A. J., Laatikainen, T. J. and Knip, M. On the association between valproate and polycystic ovary syndrome. Epilepsia 2001; 42: 295-304.
15. Isojärvi, J. I. T., Taubøll, E., Pakarinen, A. J. et al. Altered ovarian function and cardiovascular risks in valproate treated women. American Journal of Medicine 2001; 111: 290-296.
16. Genton, P., Bauer, J., Duncan, S. et al. On the association between valproate and polycystic ovary syndrome. Epilepsia 2001; 42: 295-304.
17. Aray, L. B. The degree of normal menstrual irregularity. An analysis of 20,000 calendar records from 1500 individuals. American Journal of Obstetrics and Gynecology 1939; 37: 12-29.
18. Polson, D. W., Adams, J., Wadsworth, J. and Franks, S. Polycystic ovaries: a common finding in normal women. Lancet 1988; 1: 870-872.
19. Murialdo, G., Galimberti, C. A., Magri, F. et al. Menstrual cycle and ovary alterations in women with epilepsy on antiepileptic therapy. Journal of Endocrinology 1997; 20: 519-526.
20. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30: 389-399.
21. Herzog, A. G., Seibel, M. N., Schomer, D. L., Vaitukatis, J. L. and Geschwind, N. Reproductive endocrine disorders in men with partial seizures of temporal lobe origin. Archives of Neurology 1986; 43: 347-350.
22. Morrell, M. J., Giudice, L., Flynn, K. L. et al. Predictors of ovulatory failure in women with epilepsy. Annals of Neurology 2002; 52: 696-697.
23. Taubøll, E., Wójtowicz, A. K., Ropstad, E. and Gregoraszczuk, E. L. Valproate irreversibly alters steroid secretion patterns from porcine follicular cells in vitro. Reproductive Toxicology 2002; 16: 319-325.
24. Stephen, L., Kwan, P., Shapiro, D., Dominiczak, M. and Brodie, M. J. Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy. Epilepsia 2001; 42: 1002-1008.
25. Røste, L. S., Taubøll, E., Berner, A., Isojärvi, J. I. T. and Gjerstad, L. Valproate, but not lamotrigine, induces ovarian morphological changes in Wistar rats. Experimental and Toxicological Pathology 2001; 52: 545-552.